Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     509
NP_001013725                                                           17    3301
XP_005254450                                                           17    3301
XP_005254449                                                           17    3301
XP_006719746                                                           17    4312
XP_005253685                                                           17    4312
XP_005253684                                                           17    4312
NP_003950                                                              17    4312
NP_055401                                                              16    5631
NP_079239                                                              16    7355
NP_001243000                                                           16    7355
NP_054784                                                              16    7355
NP_001275879                                                           16    7355
NP_060128                                                              16    7355
XP_005257603                                                           16    7355
XP_006722058                                                           16    7355
XP_005257602                                                           16    7355
XP_006720237                                                           16    7355
XP_005267827                                                           16    7355
XP_005267826                                                           16    7355
XP_005249911                                                           16    7355
XP_005249910                                                           16    7355
NP_060290                                                              15    9605
XP_006717224                                                           15    9605
XP_006717223                                                           15    9605
XP_006717222                                                           15    9605
XP_006717221                                                           15    9605
XP_006717220                                                           15    9605
XP_006717219                                                           15    9605
XP_006717218                                                           15    9605
XP_006717217                                                           15    9605
XP_006717216                                                           15    9605
XP_006717215                                                           15    9605
XP_006717214                                                           15    9605
XP_006713481                                                           15    9605
XP_005265642                                                           15    9605
XP_005265641                                                           15    9605
XP_006713480                                                           15    9605
XP_006713479                                                           15    9605
NP_004794                                                              15    9605
>NP_004295
          Length = 1620

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GRYIAQLL 8
           GRYIAQLL
Sbjct: 359 GRYIAQLL 366
>NP_001013725
          Length = 1649

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RY AQLLS
Sbjct: 404 RYTAQLLS 411
>XP_005254450
          Length = 1505

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RY AQLLS
Sbjct: 404 RYTAQLLS 411
>XP_005254449
          Length = 1626

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RY AQLLS
Sbjct: 404 RYTAQLLS 411
>XP_006719746
          Length = 603

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RYIAQL S
Sbjct: 367 RYIAQLKS 374
>XP_005253685
          Length = 1061

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RYIAQL S
Sbjct: 372 RYIAQLKS 379
>XP_005253684
          Length = 1073

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RYIAQL S
Sbjct: 384 RYIAQLKS 391
>NP_003950
          Length = 1068

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RYIAQL S
Sbjct: 379 RYIAQLKS 386
>NP_055401
          Length = 714

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           RYI QL+S
Sbjct: 165 RYIRQLIS 172
>NP_079239
          Length = 718

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GRYIAQLLS 9
           GR++ QLL+
Sbjct: 402 GRHLCQLLA 410
>NP_001243000
          Length = 5207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GRYIAQL 7
            GR++AQL
Sbjct: 3749 GRFLAQL 3755
>NP_054784
          Length = 679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           G Y+ QLLS
Sbjct: 552 GMYLNQLLS 560
>NP_001275879
          Length = 704

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           G Y+ QLLS
Sbjct: 552 GMYLNQLLS 560
>NP_060128
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RYIAQLLS 9
           +Y+AQLL+
Sbjct: 215 KYLAQLLN 222
>XP_005257603
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GRYIAQL 7
            GR++AQL
Sbjct: 3798 GRFLAQL 3804
>XP_006722058
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GRYIAQL 7
            GR++AQL
Sbjct: 3798 GRFLAQL 3804
>XP_005257602
          Length = 5256

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GRYIAQL 7
            GR++AQL
Sbjct: 3798 GRFLAQL 3804
>XP_006720237
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RYIAQLLS 9
           +Y+AQLL+
Sbjct: 229 KYLAQLLN 236
>XP_005267827
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RYIAQLLS 9
           +Y+AQLL+
Sbjct: 215 KYLAQLLN 222
>XP_005267826
          Length = 585

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RYIAQLLS 9
           +Y+AQLL+
Sbjct: 229 KYLAQLLN 236
>XP_005249911
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GRYIAQLLS 9
           GR++ QLL+
Sbjct: 402 GRHLCQLLA 410
>XP_005249910
          Length = 801

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GRYIAQLLS 9
           GR++ QLL+
Sbjct: 402 GRHLCQLLA 410
>NP_060290
          Length = 876

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 447 RLVAQLLS 454
>XP_006717224
          Length = 915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006717223
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 127 RLVAQLLS 134
>XP_006717222
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 127 RLVAQLLS 134
>XP_006717221
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006717220
          Length = 825

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006717219
          Length = 856

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006717218
          Length = 877

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 447 RLVAQLLS 454
>XP_006717217
          Length = 905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 475 RLVAQLLS 482
>XP_006717216
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006717215
          Length = 928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006717214
          Length = 929

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RYIAQLLS 9
           R +AQLLS
Sbjct: 499 RLVAQLLS 506
>XP_006713481
          Length = 555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           GRY A LLS
Sbjct: 223 GRYPAILLS 231
>XP_005265642
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           GRY A LLS
Sbjct: 209 GRYPAILLS 217
>XP_005265641
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           GRY A LLS
Sbjct: 209 GRYPAILLS 217
>XP_006713480
          Length = 597

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           GRY A LLS
Sbjct: 223 GRYPAILLS 231
>XP_006713479
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           GRY A LLS
Sbjct: 223 GRYPAILLS 231
>NP_004794
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GRYIAQLLS 9
           GRY A LLS
Sbjct: 209 GRYPAILLS 217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.144    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 360,508
Number of extensions: 525
Number of successful extensions: 40
Number of sequences better than 10000.0: 40
Number of HSP's gapped: 40
Number of HSP's successfully gapped: 40
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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