Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_064450                                                              20     299
XP_005273257                                                           20     299
NP_056240                                                              17    3301
XP_006712046                                                           17    3301
NP_001273700                                                           16    5631
NP_115593                                                              16    5631
NP_942592                                                              16    5631
NP_060217                                                              16    5631
NP_114130                                                              16    5631
NP_065741                                                              16    5631
XP_006723798                                                           16    5631
XP_005267210                                                           16    5631
XP_005265730                                                           16    5631
XP_005265729                                                           16    5631
XP_005265728                                                           16    5631
XP_005265724                                                           16    5631
NP_005870                                                              16    5631
NP_009045                                                              16    7355
NP_001793                                                              16    7355
XP_005276559                                                           16    7355
NP_001129706                                                           16    7355
NP_001129705                                                           16    7355
NP_001121650                                                           15    9605
NP_997064                                                              15    9605
NP_000263                                                              15    9605
NP_057336                                                              15    9605
NP_005021                                                              15    9605
NP_115946                                                              15    9605
NP_690001                                                              15    9605
NP_055990                                                              15    9605
NP_066552                                                              15    9605
NP_001277255                                                           15    9605
NP_001277254                                                           15    9605
NP_001170978                                                           15    9605
NP_065891                                                              15    9605
NP_002677                                                              15    9605
NP_004648                                                              15    9605
XP_006719578                                                           15    9605
XP_006719577                                                           15    9605
XP_006719576                                                           15    9605
XP_006719575                                                           15    9605
XP_006719574                                                           15    9605
XP_006719573                                                           15    9605
XP_005269086                                                           15    9605
XP_006719572                                                           15    9605
XP_006719571                                                           15    9605
XP_005269085                                                           15    9605
XP_006719570                                                           15    9605
XP_006719569                                                           15    9605
XP_006719568                                                           15    9605
XP_006719567                                                           15    9605
XP_005263215                                                           15    9605
XP_005265050                                                           15    9605
XP_005265049                                                           15    9605
XP_006713135                                                           15    9605
XP_006712615                                                           15    9605
XP_005263736                                                           15    9605
XP_005263735                                                           15    9605
XP_005263734                                                           15    9605
XP_005263733                                                           15    9605
XP_005263732                                                           15    9605
XP_006712614                                                           15    9605
XP_006712120                                                           15    9605
XP_005264512                                                           15    9605
XP_005264511                                                           15    9605
XP_006712119                                                           15    9605
XP_005264510                                                           15    9605
XP_006712118                                                           15    9605
XP_005264509                                                           15    9605
XP_005264508                                                           15    9605
XP_006712117                                                           15    9605
XP_005264507                                                           15    9605
XP_005264506                                                           15    9605
NP_071756                                                              15    9605
>NP_064450
          Length = 1722

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GRTLLDKLF 9
           GRTLL+KLF
Sbjct: 539 GRTLLEKLF 547
>XP_005273257
          Length = 1726

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GRTLLDKLF 9
           GRTLL+KLF
Sbjct: 539 GRTLLEKLF 547
>NP_056240
          Length = 1720

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GRTLLDKLF 9
           G++L+DKL+
Sbjct: 380 GQSLIDKLY 388
>XP_006712046
          Length = 1612

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GRTLLDKLF 9
           G++L+DKL+
Sbjct: 272 GQSLIDKLY 280
>NP_001273700
          Length = 2490

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1188 GRVLLDK 1194
>NP_115593
          Length = 2603

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1301 GRVLLDK 1307
>NP_942592
          Length = 2352

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1050 GRVLLDK 1056
>NP_060217
          Length = 2542

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1273 GRVLLDK 1279
>NP_114130
          Length = 560

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 452 GRTVLDML 459
>NP_065741
          Length = 2617

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1273 GRVLLDK 1279
>XP_006723798
          Length = 916

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GRTLLDKL 8
          GRTL +KL
Sbjct: 81 GRTLAEKL 88
>XP_005267210
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 356 GRTVLDML 363
>XP_005265730
          Length = 1480

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1301 GRVLLDK 1307
>XP_005265729
          Length = 1543

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1301 GRVLLDK 1307
>XP_005265728
          Length = 2351

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1049 GRVLLDK 1055
>XP_005265724
          Length = 2602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1    GRTLLDK 7
            GR LLDK
Sbjct: 1300 GRVLLDK 1306
>NP_005870
          Length = 469

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  RTLLDKLF 9
          RT+++KLF
Sbjct: 56 RTIINKLF 63
>NP_009045
          Length = 1093

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GRTLLDKL 8
           G+T+LDK+
Sbjct: 420 GQTVLDKV 427
>NP_001793
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GRTLLDK 7
          G+TLLD+
Sbjct: 35 GKTLLDR 41
>XP_005276559
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GRTLLDK 7
          G+TLLD+
Sbjct: 35 GKTLLDR 41
>NP_001129706
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GRTLLDKLF 9
          G+TL +KL+
Sbjct: 33 GKTLQEKLY 41
>NP_001129705
          Length = 817

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GRTLLDKLF 9
          G+TL +KL+
Sbjct: 33 GKTLQEKLY 41
>NP_001121650
          Length = 677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>NP_997064
          Length = 732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>NP_000263
          Length = 733

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>NP_057336
          Length = 4857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3940 GRTIPDKI 3947
>NP_005021
          Length = 603

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   RTLLDKL 8
           RT++DKL
Sbjct: 584 RTMVDKL 590
>NP_115946
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RTLLDKLF 9
           +TL++K+F
Sbjct: 583 KTLIEKMF 590
>NP_690001
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>NP_055990
          Length = 2754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RTLLDKLF 9
            RTLLD+ +
Sbjct: 1669 RTLLDRAY 1676
>NP_066552
          Length = 249

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GRTLLDKLF 9
           G T  DKLF
Sbjct: 161 GETTPDKLF 169
>NP_001277255
          Length = 587

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RTLLDKLF 9
           +TL++K+F
Sbjct: 128 KTLIEKMF 135
>NP_001277254
          Length = 1004

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   RTLLDKLF 9
           +TL++K+F
Sbjct: 583 KTLIEKMF 590
>NP_001170978
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GRTLLDKLF 9
          G T ++KLF
Sbjct: 38 GHTCVEKLF 46
>NP_065891
          Length = 1114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TLLDKLF 9
          TLL KLF
Sbjct: 4  TLLQKLF 10
>NP_002677
          Length = 282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  GRTLLD 6
          GRTL+D
Sbjct: 72 GRTLID 77
>NP_004648
          Length = 425

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 60 TLLDKL 65
>XP_006719578
          Length = 1067

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719577
          Length = 1184

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719576
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719575
          Length = 1200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719574
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719573
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_005269086
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719572
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719571
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_005269085
          Length = 1260

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719570
          Length = 1273

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719569
          Length = 1283

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719568
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_006719567
          Length = 1284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           GRT+LD L
Sbjct: 259 GRTVLDIL 266
>XP_005263215
          Length = 1144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  TLLDKLF 9
          TLL KLF
Sbjct: 4  TLLQKLF 10
>XP_005265050
          Length = 1578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   RTLLDKLF 9
           RTLLD+ +
Sbjct: 493 RTLLDRAY 500
>XP_005265049
          Length = 2720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RTLLDKLF 9
            RTLLD+ +
Sbjct: 1635 RTLLDRAY 1642
>XP_006713135
          Length = 2727

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    RTLLDKLF 9
            RTLLD+ +
Sbjct: 1642 RTLLDRAY 1649
>XP_006712615
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_005263736
          Length = 676

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_005263735
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_005263734
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_005263733
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_005263732
          Length = 767

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_006712614
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TLLDKL 8
          TLLDKL
Sbjct: 87 TLLDKL 92
>XP_006712120
          Length = 4812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3895 GRTIPDKI 3902
>XP_005264512
          Length = 4840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3923 GRTIPDKI 3930
>XP_005264511
          Length = 4847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3967 GRTIPDKI 3974
>XP_006712119
          Length = 4851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3934 GRTIPDKI 3941
>XP_005264510
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3944 GRTIPDKI 3951
>XP_006712118
          Length = 4864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3947 GRTIPDKI 3954
>XP_005264509
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3953 GRTIPDKI 3960
>XP_005264508
          Length = 4875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3958 GRTIPDKI 3965
>XP_006712117
          Length = 4878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3961 GRTIPDKI 3968
>XP_005264507
          Length = 4880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3963 GRTIPDKI 3970
>XP_005264506
          Length = 4884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GRTLLDKL 8
            GRT+ DK+
Sbjct: 3967 GRTIPDKI 3974
>NP_071756
          Length = 291

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GRTLLDKL 8
           G+T +DKL
Sbjct: 148 GKTSIDKL 155
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.334    0.158    0.455 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 517,756
Number of extensions: 800
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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