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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138389                                                           18    1135
NP_001138390                                                           18    1135
NP_001138386                                                           18    1135
NP_001138387                                                           18    1135
NP_000132                                                              18    1135
NP_075259                                                              18    1135
NP_001138388                                                           18    1135
NP_001138391                                                           18    1135
NP_001138385                                                           18    1135
NP_075418                                                              18    1135
XP_006717776                                                           18    1135
XP_006717775                                                           18    1135
XP_006717774                                                           18    1135
XP_006717773                                                           18    1135
XP_006717772                                                           18    1135
XP_006717771                                                           18    1135
NP_683515                                                              17    3301
NP_057672                                                              16    5631
NP_001265639                                                           16    5631
XP_005268209                                                           16    5631
XP_005268208                                                           16    5631
NP_003805                                                              16    5631
NP_996663                                                              16    7355
XP_005258026                                                           16    7355
NP_055738                                                              15    9605
NP_001265367                                                           15    9605
NP_001073141                                                           15    9605
NP_443134                                                              15    9605
XP_006719840                                                           15    9605

>NP_001138389
          Length = 705

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_001138390
          Length = 704

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_001138386
          Length = 709

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_001138387
          Length = 707

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_000132
          Length = 821

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_075259
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_001138388
          Length = 706

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_001138391
          Length = 680

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_001138385
          Length = 769

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>NP_075418
          Length = 732

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 5  GRFICLVVV 13



>XP_006717776
          Length = 806

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 24 GRFICLVVV 32



>XP_006717775
          Length = 726

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 24 GRFICLVVV 32



>XP_006717774
          Length = 752

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 24 GRFICLVVV 32



>XP_006717773
          Length = 807

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 24 GRFICLVVV 32



>XP_006717772
          Length = 838

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 24 GRFICLVVV 32



>XP_006717771
          Length = 839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRFI LVVV
Sbjct: 24 GRFICLVVV 32



>NP_683515
          Length = 1235

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GRFISLVVV 9
           GRFI+ +VV
Sbjct: 539 GRFITAIVV 547



>NP_057672
          Length = 142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GRFISLVV 8
          GR+ISL++
Sbjct: 7  GRYISLIL 14



>NP_001265639
          Length = 142

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GRFISLVV 8
          GR+ISL++
Sbjct: 7  GRYISLIL 14



>XP_005268209
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RFISLVVV 9
           RF+ LVVV
Sbjct: 257 RFVELVVV 264



>XP_005268208
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RFISLVVV 9
           RF+ LVVV
Sbjct: 257 RFVELVVV 264



>NP_003805
          Length = 776

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RFISLVVV 9
           RF+ LVVV
Sbjct: 257 RFVELVVV 264



>NP_996663
          Length = 262

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRF+ LV++
Sbjct: 12 GRFLLLVIL 20



>XP_005258026
          Length = 218

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GRFISLVVV 9
          GRF+ LV++
Sbjct: 12 GRFLLLVIL 20



>NP_055738
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GRFISL 6
           GRF+SL
Sbjct: 939 GRFVSL 944



>NP_001265367
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    GRFISL 6
            GRF+SL
Sbjct: 995  GRFVSL 1000



>NP_001073141
          Length = 1198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    GRFISL 6
            GRF+SL
Sbjct: 995  GRFVSL 1000



>NP_443134
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GRFISLVVV 9
           G F+ LVVV
Sbjct: 834 GEFMCLVVV 842



>XP_006719840
          Length = 1080

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GRFISL 6
           GRF+SL
Sbjct: 877 GRFVSL 882



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.161    0.435 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 322,639
Number of extensions: 528
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)