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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1135
XP_005262424                                                           18    1135
NP_689599                                                              17    2528
XP_005246354                                                           17    2528
NP_667338                                                              17    4312
NP_001159608                                                           17    4312
XP_006713923                                                           17    4312
XP_006713922                                                           17    4312
NP_878917                                                              16    5631
NP_878914                                                              16    5631
NP_878918                                                              16    5631
NP_055995                                                              16    5631
NP_075044                                                              16    5631
XP_005267517                                                           16    5631
XP_005267516                                                           16    5631
XP_005267515                                                           16    5631
XP_005267514                                                           16    5631
XP_005267513                                                           16    5631
XP_005267512                                                           16    5631
XP_005267511                                                           16    5631
NP_061748                                                              16    7355
NP_115270                                                              16    7355
NP_005100                                                              15    9605
NP_116281                                                              15    9605
NP_001273419                                                           15    9605
NP_001273420                                                           15    9605
NP_055685                                                              15    9605
NP_079225                                                              15    9605
NP_005133                                                              15    9605
NP_001276876                                                           15    9605
NP_001276959                                                           15    9605
XP_005254787                                                           15    9605
XP_005254786                                                           15    9605
XP_005273967                                                           15    9605
XP_006714375                                                           15    9605
XP_005265695                                                           15    9605
NP_001077090                                                           15    9605

>NP_722576
          Length = 3080

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GQVSKDVMA 9
            G VSKDVMA
Sbjct: 1928 GLVSKDVMA 1936



>XP_005262424
          Length = 2875

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GQVSKDVMA 9
            G VSKDVMA
Sbjct: 1723 GLVSKDVMA 1731



>NP_689599
          Length = 399

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GQVSKDVM 8
           GQV+KDV+
Sbjct: 132 GQVAKDVL 139



>XP_005246354
          Length = 271

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1  GQVSKDVM 8
          GQV+KDV+
Sbjct: 4  GQVAKDVL 11



>NP_667338
          Length = 1308

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVSKDVMA 9
           Q+SKD++A
Sbjct: 401 QISKDIIA 408



>NP_001159608
          Length = 1228

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVSKDVMA 9
           Q+SKD++A
Sbjct: 321 QISKDIIA 328



>XP_006713923
          Length = 1228

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVSKDVMA 9
           Q+SKD++A
Sbjct: 321 QISKDIIA 328



>XP_006713922
          Length = 1262

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QVSKDVMA 9
           Q+SKD++A
Sbjct: 401 QISKDIIA 408



>NP_878917
          Length = 556

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVSKDVMA 9
           QVS+D+MA
Sbjct: 430 QVSQDLMA 437



>NP_878914
          Length = 429

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QVSKDVMA 9
           QVS+D+MA
Sbjct: 304 QVSQDLMA 311



>NP_878918
          Length = 6907

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6782 QVSQDLMA 6789



>NP_055995
          Length = 6885

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6759 QVSQDLMA 6766



>NP_075044
          Length = 835

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GQVSKDV 7
           GQV KDV
Sbjct: 793 GQVGKDV 799



>XP_005267517
          Length = 6883

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6757 QVSQDLMA 6764



>XP_005267516
          Length = 6884

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6759 QVSQDLMA 6766



>XP_005267515
          Length = 6899

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6773 QVSQDLMA 6780



>XP_005267514
          Length = 6908

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6782 QVSQDLMA 6789



>XP_005267513
          Length = 6921

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6796 QVSQDLMA 6803



>XP_005267512
          Length = 6922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6796 QVSQDLMA 6803



>XP_005267511
          Length = 6922

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    QVSKDVMA 9
            QVS+D+MA
Sbjct: 6796 QVSQDLMA 6803



>NP_061748
          Length = 923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQVSKDVMA 9
           GQVS  +MA
Sbjct: 481 GQVSYSIMA 489



>NP_115270
          Length = 818

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQVSKDVMA 9
           GQVS  +MA
Sbjct: 481 GQVSYSIMA 489



>NP_005100
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQVSKDVMA 9
           GQ+ +DV A
Sbjct: 141 GQIHRDVKA 149



>NP_116281
          Length = 570

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GQVSKDVM 8
           G+V+K+VM
Sbjct: 321 GRVAKEVM 328



>NP_001273419
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GQVSKDVM 8
           G+V+K+VM
Sbjct: 227 GRVAKEVM 234



>NP_001273420
          Length = 336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GQVSKDVM 8
          G+V+K+VM
Sbjct: 87 GRVAKEVM 94



>NP_055685
          Length = 1239

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQVSKDVMA 9
           GQV +DV A
Sbjct: 123 GQVVRDVSA 131



>NP_079225
          Length = 1192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    QVSKDV 7
            QVSKDV
Sbjct: 1148 QVSKDV 1153



>NP_005133
          Length = 417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GQVSKDVM 8
           GQV KD++
Sbjct: 200 GQVLKDIV 207



>NP_001276876
          Length = 156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GQVSKDVM 8
          G+VSKD +
Sbjct: 10 GEVSKDAV 17



>NP_001276959
          Length = 436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GQVSKDVM 8
           G+VSKD +
Sbjct: 290 GEVSKDAV 297



>XP_005254787
          Length = 517

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GQVSKDVM 8
           G+V+K+VM
Sbjct: 321 GRVAKEVM 328



>XP_005254786
          Length = 565

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GQVSKDVM 8
           G+V+K+VM
Sbjct: 316 GRVAKEVM 323



>XP_005273967
          Length = 392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GQVSKDVM 8
           GQV KD++
Sbjct: 175 GQVLKDIV 182



>XP_006714375
          Length = 1208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2    QVSKDV 7
            QVSKDV
Sbjct: 1164 QVSKDV 1169



>XP_005265695
          Length = 460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GQVSKDVMA 9
          GQ+ +DV A
Sbjct: 74 GQIHRDVKA 82



>NP_001077090
          Length = 1239

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQVSKDVMA 9
           GQV +DV A
Sbjct: 123 GQVVRDVSA 131



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.121    0.304 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 430,494
Number of extensions: 471
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)