Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              18    1935
XP_005269721                                                           18    1935
NP_003226                                                              17    4312
NP_031371                                                              17    4312
XP_005266819                                                           17    4312
XP_006722604                                                           17    4312
XP_005251100                                                           17    4312
XP_006716686                                                           17    4312
XP_005251099                                                           17    4312
XP_005251097                                                           17    4312
XP_005251095                                                           17    4312
XP_006716685                                                           17    4312
NP_001274152                                                           16    5631
NP_001244286                                                           16    5631
NP_054858                                                              16    5631
NP_001074295                                                           16    7355
NP_001245207                                                           16    7355
NP_001245205                                                           16    7355
NP_001245206                                                           16    7355
XP_005272427                                                           16    7355
XP_005272426                                                           16    7355
XP_005266874                                                           16    7355
XP_005266873                                                           16    7355
NP_443145                                                              16    7355
NP_036222                                                              15    9605
NP_694558                                                              15    9605
NP_112210                                                              15    9605
NP_001274270                                                           15    9605
NP_001078880                                                           15    9605
NP_001229577                                                           15    9605
NP_001274269                                                           15    9605
NP_065852                                                              15    9605
NP_001137236                                                           15    9605
NP_001137235                                                           15    9605
NP_055690                                                              15    9605
XP_005248994                                                           15    9605
XP_005248993                                                           15    9605
XP_005248992                                                           15    9605
XP_005248990                                                           15    9605
XP_005248991                                                           15    9605
XP_006715084                                                           15    9605
XP_005248298                                                           15    9605
XP_006710599                                                           15    9605
XP_006710598                                                           15    9605
XP_006710596                                                           15    9605
XP_006710595                                                           15    9605
XP_006710594                                                           15    9605
XP_006710593                                                           15    9605
XP_006710592                                                           15    9605
XP_006710591                                                           15    9605
XP_006710590                                                           15    9605
XP_006710589                                                           15    9605
XP_006710587                                                           15    9605
XP_006710586                                                           15    9605
XP_006710585                                                           15    9605
XP_005270755                                                           15    9605
XP_006710584                                                           15    9605
XP_005270754                                                           15    9605
XP_005270753                                                           15    9605
XP_006710583                                                           15    9605
XP_005270752                                                           15    9605
XP_006710582                                                           15    9605
XP_005270751                                                           15    9605
XP_006710306                                                           15    9605
>NP_036462
          Length = 2073

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           GQS SSQKS
Sbjct: 502 GQSPSSQKS 510
>XP_005269721
          Length = 2073

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           GQS SSQKS
Sbjct: 502 GQSPSSQKS 510
>NP_003226
          Length = 2768

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876
>NP_031371
          Length = 1845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GQSLSSQK 8
            G SLSSQK
Sbjct: 1711 GPSLSSQK 1718
>XP_005266819
          Length = 1790

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GQSLSSQK 8
            G SLSSQK
Sbjct: 1656 GPSLSSQK 1663
>XP_006722604
          Length = 1847

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GQSLSSQK 8
            G SLSSQK
Sbjct: 1713 GPSLSSQK 1720
>XP_005251100
          Length = 2103

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876
>XP_006716686
          Length = 2111

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876
>XP_005251099
          Length = 2121

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876
>XP_005251097
          Length = 2178

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876
>XP_005251095
          Length = 2704

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1806 QSLSSQK 1812
>XP_006716685
          Length = 2747

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    QSLSSQK 8
            QSLSSQK
Sbjct: 1870 QSLSSQK 1876
>NP_001274152
          Length = 1791

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+S +SQKS
Sbjct: 724 GRSFNSQKS 732
>NP_001244286
          Length = 1021

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           GQ LSS++S
Sbjct: 686 GQDLSSEQS 694
>NP_054858
          Length = 1791

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+S +SQKS
Sbjct: 724 GRSFNSQKS 732
>NP_001074295
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           GQ LSS++S
Sbjct: 520 GQGLSSRES 528
>NP_001245207
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQSLSSQ 7
           G+SLSSQ
Sbjct: 352 GESLSSQ 358
>NP_001245205
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQSLSSQ 7
           G+SLSSQ
Sbjct: 352 GESLSSQ 358
>NP_001245206
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQSLSSQ 7
           G+SLSSQ
Sbjct: 352 GESLSSQ 358
>XP_005272427
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           GQ LSS++S
Sbjct: 520 GQGLSSRES 528
>XP_005272426
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           GQ LSS++S
Sbjct: 520 GQGLSSRES 528
>XP_005266874
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQSLSSQ 7
           G+SLSSQ
Sbjct: 352 GESLSSQ 358
>XP_005266873
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQSLSSQ 7
           G+SLSSQ
Sbjct: 352 GESLSSQ 358
>NP_443145
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQSLSSQ 7
           G+SLSSQ
Sbjct: 352 GESLSSQ 358
>NP_036222
          Length = 5430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 3450 GQSLSSLTS 3458
>NP_694558
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+SLSS+ S
Sbjct: 118 GESLSSRAS 126
>NP_112210
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSLSSQK 8
           GQSLSS +
Sbjct: 181 GQSLSSSQ 188
>NP_001274270
          Length = 301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+SLSS+ S
Sbjct: 118 GESLSSRMS 126
>NP_001078880
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+SLSS+ S
Sbjct: 281 GESLSSRAS 289
>NP_001229577
          Length = 580

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSLSSQK 8
           GQSLSS +
Sbjct: 181 GQSLSSSQ 188
>NP_001274269
          Length = 279

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+SLSS+ S
Sbjct: 118 GESLSSRAS 126
>NP_065852
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+SLSS K+
Sbjct: 252 GESLSSGKT 260
>NP_001137236
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  GQSLSSQK 8
          GQ  SSQK
Sbjct: 25 GQDTSSQK 32
>NP_001137235
          Length = 318

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  GQSLSSQK 8
          GQ  SSQK
Sbjct: 25 GQDTSSQK 32
>NP_055690
          Length = 1648

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QSLSSQKS 9
           Q LSSQK+
Sbjct: 967 QELSSQKA 974
>XP_005248994
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GQSLSSQK 8
          GQSLSS +
Sbjct: 89 GQSLSSSQ 96
>XP_005248993
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GQSLSSQK 8
          GQSLSS +
Sbjct: 89 GQSLSSSQ 96
>XP_005248992
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSLSSQK 8
           GQSLSS +
Sbjct: 181 GQSLSSSQ 188
>XP_005248990
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSLSSQK 8
           GQSLSS +
Sbjct: 181 GQSLSSSQ 188
>XP_005248991
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSLSSQK 8
           GQSLSS +
Sbjct: 181 GQSLSSSQ 188
>XP_006715084
          Length = 650

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSLSSQK 8
           GQSLSS +
Sbjct: 182 GQSLSSSQ 189
>XP_005248298
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQSLSSQKS 9
           G+SLSS+ S
Sbjct: 281 GESLSSRMS 289
>XP_006710599
          Length = 5656

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 3610 GQSLSSLTS 3618
>XP_006710598
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5507 GQSLSSLTS 5515
>XP_006710596
          Length = 7512

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5466 GQSLSSLTS 5474
>XP_006710595
          Length = 7526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5480 GQSLSSLTS 5488
>XP_006710594
          Length = 7528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5482 GQSLSSLTS 5490
>XP_006710593
          Length = 7539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5493 GQSLSSLTS 5501
>XP_006710592
          Length = 7544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5498 GQSLSSLTS 5506
>XP_006710591
          Length = 7558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5512 GQSLSSLTS 5520
>XP_006710590
          Length = 7563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5517 GQSLSSLTS 5525
>XP_006710589
          Length = 7595

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5549 GQSLSSLTS 5557
>XP_006710587
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5599 GQSLSSLTS 5607
>XP_006710586
          Length = 7645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_006710585
          Length = 7657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_005270755
          Length = 7663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_006710584
          Length = 7686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_005270754
          Length = 7694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_005270753
          Length = 7700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_006710583
          Length = 7702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5656 GQSLSSLTS 5664
>XP_005270752
          Length = 7717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_006710582
          Length = 7720

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_005270751
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GQSLSSQKS 9
            GQSLSS  S
Sbjct: 5677 GQSLSSLTS 5685
>XP_006710306
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQSLSSQKS 9
           GQSL  Q+S
Sbjct: 92  GQSLGLQRS 100
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.277   0.0947    0.205 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,856
Number of extensions: 819
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 18 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.6 bits)
S2: 28 (15.4 bits)

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