Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              21     229
NP_001120965                                                           16    5631
NP_066187                                                              16    5631
NP_001139                                                              16    5631
NP_859063                                                              16    5631
XP_006714256                                                           16    5631
XP_006714255                                                           16    5631
XP_005263005                                                           16    5631
XP_006714254                                                           16    5631
XP_006714253                                                           16    5631
XP_005263002                                                           16    5631
XP_005262999                                                           16    5631
XP_006714252                                                           16    5631
XP_006714251                                                           16    5631
NP_005518                                                              16    7355
NP_006083                                                              16    7355
NP_775833                                                              16    7355
NP_056386                                                              16    7355
NP_001273508                                                           16    7355
NP_001273509                                                           16    7355
XP_005275459                                                           16    7355
XP_005275458                                                           16    7355
XP_005275456                                                           16    7355
XP_005275031                                                           16    7355
XP_005275030                                                           16    7355
XP_005275027                                                           16    7355
XP_005272874                                                           16    7355
XP_005272873                                                           16    7355
XP_005272870                                                           16    7355
XP_005274919                                                           16    7355
XP_005274918                                                           16    7355
XP_005274916                                                           16    7355
XP_006715700                                                           16    7355
XP_006715699                                                           16    7355
XP_005249632                                                           16    7355
XP_005249631                                                           16    7355
XP_005249630                                                           16    7355
XP_006715698                                                           16    7355
XP_006715697                                                           16    7355
XP_005249629                                                           16    7355
XP_006715696                                                           16    7355
XP_005249625                                                           16    7355
XP_006715520                                                           16    7355
XP_005249128                                                           16    7355
XP_005249130                                                           16    7355
XP_005249127                                                           16    7355
XP_006715086                                                           16    7355
XP_005248997                                                           16    7355
NP_001093879                                                           16    7355
NP_060250                                                              15    9605
XP_006716523                                                           15    9605
XP_006716522                                                           15    9605
XP_005251324                                                           15    9605
XP_005251323                                                           15    9605
>NP_115803
          Length = 1156

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           GQSKVM NY
Sbjct: 505 GQSKVMANY 513
>NP_001120965
          Length = 1863

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 200 QSKMMVN 206
>NP_066187
          Length = 1872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 221 QSKMMVN 227
>NP_001139
          Length = 3957

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 221 QSKMMVN 227
>NP_859063
          Length = 995

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQSKVMVN 8
           GQ+ VMVN
Sbjct: 408 GQTDVMVN 415
>XP_006714256
          Length = 1901

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714255
          Length = 1970

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_005263005
          Length = 2019

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714254
          Length = 2049

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714253
          Length = 2069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_005263002
          Length = 4072

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 221 QSKMMVN 227
>XP_005262999
          Length = 4147

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714252
          Length = 4153

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>XP_006714251
          Length = 4165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSK+MVN
Sbjct: 253 QSKMMVN 259
>NP_005518
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>NP_006083
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>NP_775833
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+S+V+ NY
Sbjct: 337 GRSEVIYNY 345
>NP_056386
          Length = 1112

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQSKVMVNY 9
           G SK+ +NY
Sbjct: 907 GLSKIRLNY 915
>NP_001273508
          Length = 253

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+S+V+ NY
Sbjct: 171 GRSEVIYNY 179
>NP_001273509
          Length = 274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+S+V+ NY
Sbjct: 192 GRSEVIYNY 200
>XP_005275459
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005275458
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005275456
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 165 GKPKVLVSY 173
>XP_005275031
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005275030
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005275027
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 165 GKPKVLVSY 173
>XP_005272874
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005272873
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005272870
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 165 GKPKVLVSY 173
>XP_005274919
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005274918
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005274916
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 165 GKPKVLVSY 173
>XP_006715700
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715699
          Length = 779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249632
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249631
          Length = 869

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249630
          Length = 925

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715698
          Length = 937

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715697
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249629
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715696
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_005249625
          Length = 953

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QSKVMVN 8
           QSKV+VN
Sbjct: 116 QSKVVVN 122
>XP_006715520
          Length = 1056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQSKVMVNY 9
           G SK+ +NY
Sbjct: 851 GLSKIRLNY 859
>XP_005249128
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005249130
          Length = 641

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 101 GKPKVLVSY 109
>XP_005249127
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+ KV+V+Y
Sbjct: 165 GKPKVLVSY 173
>XP_006715086
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+S+V+ NY
Sbjct: 337 GRSEVIYNY 345
>XP_005248997
          Length = 419

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           G+S+V+ NY
Sbjct: 337 GRSEVIYNY 345
>NP_001093879
          Length = 1105

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQSKVMVNY 9
           G SK+ +NY
Sbjct: 900 GLSKIRLNY 908
>NP_060250
          Length = 2997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    GQSKVMVNY 9
            GQ++ +VN+
Sbjct: 1674 GQTRALVNH 1682
>XP_006716523
          Length = 1912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           GQ++ +VN+
Sbjct: 589 GQTRALVNH 597
>XP_006716522
          Length = 2192

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GQSKVMVNY 9
           GQ++ +VN+
Sbjct: 869 GQTRALVNH 877
>XP_005251324
          Length = 2996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    GQSKVMVNY 9
            GQ++ +VN+
Sbjct: 1674 GQTRALVNH 1682
>XP_005251323
          Length = 2997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    GQSKVMVNY 9
            GQ++ +VN+
Sbjct: 1674 GQTRALVNH 1682
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.312    0.126    0.338 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 347,781
Number of extensions: 504
Number of successful extensions: 54
Number of sequences better than 10000.0: 54
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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