Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001177957                                                           20     299
NP_036602                                                              20     299
XP_006715974                                                           20     299
NP_699179                                                              17    3301
NP_001108070                                                           17    3301
XP_006723324                                                           17    3301
XP_005253923                                                           17    3301
NP_055752                                                              17    4312
XP_006717783                                                           17    4312
XP_006717782                                                           17    4312
NP_057006                                                              16    5631
NP_001123237                                                           16    5631
XP_006724887                                                           16    5631
XP_005261462                                                           16    7355
XP_006713531                                                           16    7355
XP_006713529                                                           16    7355
XP_006713528                                                           16    7355
XP_006713527                                                           16    7355
XP_006713526                                                           16    7355
XP_006713524                                                           16    7355
XP_006713523                                                           16    7355
NP_079133                                                              15    9605
NP_057336                                                              15    9605
NP_001229792                                                           15    9605
NP_060463                                                              15    9605
NP_001026895                                                           15    9605
NP_001171696                                                           15    9605
NP_001138462                                                           15    9605
NP_699177                                                              15    9605
NP_001121087                                                           15    9605
NP_005299                                                              15    9605
NP_001230706                                                           15    9605
NP_001230705                                                           15    9605
NP_055494                                                              15    9605
NP_862820                                                              15    9605
NP_001184188                                                           15    9605
NP_036513                                                              15    9605
XP_006719905                                                           15    9605
XP_006719904                                                           15    9605
XP_005266496                                                           15    9605
XP_005266495                                                           15    9605
XP_006719009                                                           15    9605
XP_006719008                                                           15    9605
XP_005269765                                                           15    9605
XP_005269764                                                           15    9605
XP_005269454                                                           15    9605
XP_005269453                                                           15    9605
XP_005269452                                                           15    9605
XP_005269451                                                           15    9605
XP_005269449                                                           15    9605
XP_005269448                                                           15    9605
XP_005269446                                                           15    9605
XP_005269445                                                           15    9605
XP_005248763                                                           15    9605
XP_005248762                                                           15    9605
XP_005248761                                                           15    9605
XP_006712120                                                           15    9605
XP_005264512                                                           15    9605
XP_005264511                                                           15    9605
XP_006712119                                                           15    9605
XP_005264510                                                           15    9605
XP_006712118                                                           15    9605
XP_005264509                                                           15    9605
XP_005264508                                                           15    9605
XP_006712117                                                           15    9605
XP_005264507                                                           15    9605
XP_005264506                                                           15    9605
XP_006711625                                                           15    9605
XP_005245577                                                           15    9605
XP_005245576                                                           15    9605
NP_060030                                                              15    9605
>NP_001177957
          Length = 859

 Score = 20.4 bits (41), Expect =   299
 Identities = 9/9 (100%), Positives = 9/9 (100%)

Query: 1   GQQLVSQLL 9
           GQQLVSQLL
Sbjct: 766 GQQLVSQLL 774
>NP_036602
          Length = 923

 Score = 20.4 bits (41), Expect =   299
 Identities = 9/9 (100%), Positives = 9/9 (100%)

Query: 1   GQQLVSQLL 9
           GQQLVSQLL
Sbjct: 830 GQQLVSQLL 838
>XP_006715974
          Length = 875

 Score = 20.4 bits (41), Expect =   299
 Identities = 9/9 (100%), Positives = 9/9 (100%)

Query: 1   GQQLVSQLL 9
           GQQLVSQLL
Sbjct: 782 GQQLVSQLL 790
>NP_699179
          Length = 598

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQQLVSQLL 9
           G+QLV QL+
Sbjct: 95  GEQLVDQLI 103
>NP_001108070
          Length = 283

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          GQ LVS+LL
Sbjct: 18 GQSLVSRLL 26
>XP_006723324
          Length = 420

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GQQLVSQLL 9
           GQ LVS+LL
Sbjct: 135 GQSLVSRLL 143
>XP_005253923
          Length = 422

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQQLVSQLL 9
           G+QLV QL+
Sbjct: 95  GEQLVDQLI 103
>NP_055752
          Length = 1132

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQLL
Sbjct: 596 QELISQLL 603
>XP_006717783
          Length = 641

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQLL
Sbjct: 596 QELISQLL 603
>XP_006717782
          Length = 1089

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQLL
Sbjct: 553 QELISQLL 560
>NP_057006
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GQQLVSQLL 9
          GQ +V QLL
Sbjct: 50 GQHMVEQLL 58
>NP_001123237
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GQQLVSQLL 9
          GQ +V QLL
Sbjct: 50 GQHMVEQLL 58
>XP_006724887
          Length = 373

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GQQLVSQLL 9
          GQ +V QLL
Sbjct: 50 GQHMVEQLL 58
>XP_005261462
          Length = 2473

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GQQLVSQL 8
            G+QL+S+L
Sbjct: 1845 GEQLISRL 1852
>XP_006713531
          Length = 566

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>XP_006713529
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>XP_006713528
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>XP_006713527
          Length = 1115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>XP_006713526
          Length = 1118

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>XP_006713524
          Length = 1131

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>XP_006713523
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQQLVSQLL 9
          G+QLVS L+
Sbjct: 8  GEQLVSPLV 16
>NP_079133
          Length = 1844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GQQLVSQL 8
            G+Q++SQL
Sbjct: 1164 GRQILSQL 1171
>NP_057336
          Length = 4857

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 2988 QQIMSQIL 2995
>NP_001229792
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GQQLVS 6
          GQQLVS
Sbjct: 64 GQQLVS 69
>NP_060463
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GQQLVS 6
          GQQLVS
Sbjct: 64 GQQLVS 69
>NP_001026895
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>NP_001171696
          Length = 645

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GQQLVSQL 8
           G Q+VSQ+
Sbjct: 129 GDQIVSQI 136
>NP_001138462
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQQLVSQLL 9
           GQ+LVS+ L
Sbjct: 654 GQKLVSRAL 662
>NP_699177
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GQQLVSQL 8
           G Q+VSQ+
Sbjct: 129 GDQIVSQI 136
>NP_001121087
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GQQLVS 6
          GQQLVS
Sbjct: 64 GQQLVS 69
>NP_005299
          Length = 590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GQQLVSQ 7
           GQ LVSQ
Sbjct: 122 GQDLVSQ 128
>NP_001230706
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>NP_001230705
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           Q+L SQLL
Sbjct: 118 QELTSQLL 125
>NP_055494
          Length = 500

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>NP_862820
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQL+
Sbjct: 149 QKLISQLM 156
>NP_001184188
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  QQLVSQLL 9
          Q+L+SQL+
Sbjct: 6  QKLISQLM 13
>NP_036513
          Length = 711

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQL+
Sbjct: 149 QKLISQLM 156
>XP_006719905
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GQQLVS 6
          GQQLVS
Sbjct: 64 GQQLVS 69
>XP_006719904
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GQQLVS 6
          GQQLVS
Sbjct: 64 GQQLVS 69
>XP_005266496
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GQQLVS 6
          GQQLVS
Sbjct: 64 GQQLVS 69
>XP_005266495
          Length = 678

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   GQQLVS 6
           GQQLVS
Sbjct: 99  GQQLVS 104
>XP_006719009
          Length = 438

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>XP_006719008
          Length = 461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           Q+L SQLL
Sbjct: 127 QELTSQLL 134
>XP_005269765
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GQQLVSQ 7
          GQ LVSQ
Sbjct: 90 GQDLVSQ 96
>XP_005269764
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GQQLVSQ 7
           GQ LVSQ
Sbjct: 122 GQDLVSQ 128
>XP_005269454
          Length = 2912

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2449 GKQLCSQL 2456
>XP_005269453
          Length = 2922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2536 GKQLCSQL 2543
>XP_005269452
          Length = 2954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2491 GKQLCSQL 2498
>XP_005269451
          Length = 2957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2494 GKQLCSQL 2501
>XP_005269449
          Length = 2969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2536 GKQLCSQL 2543
>XP_005269448
          Length = 2979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2516 GKQLCSQL 2523
>XP_005269446
          Length = 2999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2536 GKQLCSQL 2543
>XP_005269445
          Length = 2999

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GQQLVSQL 8
            G+QL SQL
Sbjct: 2536 GKQLCSQL 2543
>XP_005248763
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQL+
Sbjct: 96  QKLISQLM 103
>XP_005248762
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQL+
Sbjct: 96  QKLISQLM 103
>XP_005248761
          Length = 684

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QQLVSQLL 9
           Q+L+SQL+
Sbjct: 149 QKLISQLM 156
>XP_006712120
          Length = 4812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 2943 QQIMSQIL 2950
>XP_005264512
          Length = 4840

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 2971 QQIMSQIL 2978
>XP_005264511
          Length = 4847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3015 QQIMSQIL 3022
>XP_006712119
          Length = 4851

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 2982 QQIMSQIL 2989
>XP_005264510
          Length = 4861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 2992 QQIMSQIL 2999
>XP_006712118
          Length = 4864

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3015 QQIMSQIL 3022
>XP_005264509
          Length = 4870

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3001 QQIMSQIL 3008
>XP_005264508
          Length = 4875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3006 QQIMSQIL 3013
>XP_006712117
          Length = 4878

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3009 QQIMSQIL 3016
>XP_005264507
          Length = 4880

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3011 QQIMSQIL 3018
>XP_005264506
          Length = 4884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2    QQLVSQLL 9
            QQ++SQ+L
Sbjct: 3015 QQIMSQIL 3022
>XP_006711625
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>XP_005245577
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>XP_005245576
          Length = 576

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QQLVSQLL 9
           +QL SQLL
Sbjct: 392 EQLASQLL 399
>NP_060030
          Length = 659

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GQQLVSQL 8
           GQQ +SQL
Sbjct: 126 GQQQLSQL 133
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.135    0.327 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 347,579
Number of extensions: 658
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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