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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              19     665
XP_005267290                                                           19     665
NP_443109                                                              17    2528
NP_963836                                                              17    2528
NP_003473                                                              17    3301
XP_006719679                                                           17    3301
XP_005269219                                                           17    3301
XP_006719678                                                           17    3301
XP_006719677                                                           17    3301
NP_055544                                                              17    4312
XP_005260507                                                           17    4312
XP_006723885                                                           17    4312
NP_955459                                                              17    4312
NP_078858                                                              16    5631
NP_001278232                                                           16    5631
NP_001278214                                                           16    5631
NP_079435                                                              16    7355
NP_733468                                                              15    9605
NP_653091                                                              15    9605
NP_001139283                                                           15    9605
NP_201583                                                              15    9605
NP_059978                                                              15    9605
NP_001139291                                                           15    9605
NP_001072983                                                           15    9605
NP_006198                                                              15    9605
NP_001274731                                                           15    9605
NP_003184                                                              15    9605
NP_001274730                                                           15    9605

>NP_005091
          Length = 1782

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GQLSTINSV 9
          GQLSTIN V
Sbjct: 60 GQLSTINGV 68



>XP_005267290
          Length = 1782

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GQLSTINSV 9
          GQLSTIN V
Sbjct: 60 GQLSTINGV 68



>NP_443109
          Length = 301

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQLSTINSV 9
          GQL+T+N V
Sbjct: 54 GQLNTLNKV 62



>NP_963836
          Length = 268

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GQLSTINSV 9
          GQL+T+N V
Sbjct: 54 GQLNTLNKV 62



>NP_003473
          Length = 5537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    GQLSTINSV 9
            GQLSTI+ V
Sbjct: 2013 GQLSTISPV 2021



>XP_006719679
          Length = 5536

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    GQLSTINSV 9
            GQLSTI+ V
Sbjct: 2012 GQLSTISPV 2020



>XP_005269219
          Length = 5537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    GQLSTINSV 9
            GQLSTI+ V
Sbjct: 2013 GQLSTISPV 2021



>XP_006719678
          Length = 5539

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    GQLSTINSV 9
            GQLSTI+ V
Sbjct: 2015 GQLSTISPV 2023



>XP_006719677
          Length = 5540

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1    GQLSTINSV 9
            GQLSTI+ V
Sbjct: 2016 GQLSTISPV 2024



>NP_055544
          Length = 526

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GQLSTIN 7
           GQL+TIN
Sbjct: 177 GQLTTIN 183



>XP_005260507
          Length = 426

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GQLSTINSV 9
           GQLST+ SV
Sbjct: 405 GQLSTLVSV 413



>XP_006723885
          Length = 448

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GQLSTINSV 9
           GQLST+ SV
Sbjct: 427 GQLSTLVSV 435



>NP_955459
          Length = 645

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GQLSTINSV 9
           GQLST+ SV
Sbjct: 624 GQLSTLVSV 632



>NP_078858
          Length = 4981

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LSTI+S+
Sbjct: 639 GRLSTISSL 647



>NP_001278232
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LSTI+S+
Sbjct: 639 GRLSTISSL 647



>NP_001278214
          Length = 4982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LSTI+S+
Sbjct: 639 GRLSTISSL 647



>NP_079435
          Length = 301

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQLSTINSV 9
           GQ+  INSV
Sbjct: 132 GQVMAINSV 140



>NP_733468
          Length = 2342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GQLSTIN 7
           GQL+T+N
Sbjct: 818 GQLTTMN 824



>NP_653091
          Length = 2316

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GQLSTIN 7
           GQL+T+N
Sbjct: 792 GQLTTMN 798



>NP_001139283
          Length = 801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LS+IN++
Sbjct: 497 GKLSSINNM 505



>NP_201583
          Length = 808

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LS+IN++
Sbjct: 524 GKLSSINNM 532



>NP_059978
          Length = 804

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LS+IN++
Sbjct: 500 GKLSSINNM 508



>NP_001139291
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GQLSTINSV 9
           G+LS+IN++
Sbjct: 537 GKLSSINNM 545



>NP_001072983
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GQLSTIN 7
           GQL T+N
Sbjct: 363 GQLKTLN 369



>NP_006198
          Length = 375

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GQLSTINS 8
           GQL+ +NS
Sbjct: 126 GQLTLVNS 133



>NP_001274731
          Length = 414

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GQLSTIN 7
           GQL T+N
Sbjct: 250 GQLKTLN 256



>NP_003184
          Length = 527

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GQLSTIN 7
           GQL T+N
Sbjct: 363 GQLKTLN 369



>NP_001274730
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GQLSTIN 7
           GQL T+N
Sbjct: 414 GQLKTLN 420



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.303    0.120    0.292 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 310,115
Number of extensions: 387
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.3 bits)
S2: 28 (15.4 bits)