Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_036462                                                              20     509
NP_001243397                                                           20     509
XP_005269721                                                           20     509
NP_001229416                                                           17    4312
NP_001229417                                                           17    4312
NP_055852                                                              17    4312
XP_005269712                                                           17    4312
XP_006717788                                                           17    4312
XP_005269710                                                           17    4312
XP_005269709                                                           17    4312
XP_005269708                                                           17    4312
XP_005269706                                                           17    4312
XP_005269705                                                           17    4312
NP_958441                                                              16    7355
NP_958439                                                              16    7355
NP_005219                                                              16    7355
NP_001699                                                              16    7355
NP_001185744                                                           16    7355
XP_005275558                                                           16    7355
XP_005275391                                                           16    7355
XP_005275259                                                           16    7355
XP_005274965                                                           16    7355
XP_005272815                                                           16    7355
XP_005274885                                                           16    7355
XP_005248836                                                           16    7355
NP_001136061                                                           15    9605
NP_001136060                                                           15    9605
NP_001136059                                                           15    9605
NP_001136062                                                           15    9605
NP_055038                                                              15    9605
XP_006710725                                                           15    9605
XP_005270953                                                           15    9605
XP_006710724                                                           15    9605
XP_006710723                                                           15    9605
XP_005270951                                                           15    9605
XP_005270950                                                           15    9605
XP_005270948                                                           15    9605
XP_006710722                                                           15    9605
XP_006710721                                                           15    9605
XP_006710720                                                           15    9605
XP_006710719                                                           15    9605
XP_005270952                                                           15    9605



>NP_036462
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           GQKTKV TT
Sbjct: 375 GQKTKVCTT 383






 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           G  TK++TT
Sbjct: 408 GATTKITTT 416





>NP_001243397
          Length = 1890

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           GQKTKV TT
Sbjct: 375 GQKTKVCTT 383






 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           G  TK++TT
Sbjct: 408 GATTKITTT 416





>XP_005269721
          Length = 2073

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           GQKTKV TT
Sbjct: 375 GQKTKVCTT 383






 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           G  TK++TT
Sbjct: 408 GATTKITTT 416





>NP_001229416
          Length = 1837

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>NP_001229417
          Length = 1892

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>NP_055852
          Length = 1842

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>XP_005269712
          Length = 1800

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 782 GKKNKVSTS 790





>XP_006717788
          Length = 1829

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>XP_005269710
          Length = 1834

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>XP_005269709
          Length = 1871

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 782 GKKNKVSTS 790





>XP_005269708
          Length = 1897

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>XP_005269706
          Length = 1900

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>XP_005269705
          Length = 1905

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GQKTKVSTT 9
           G+K KVST+
Sbjct: 816 GKKNKVSTS 824





>NP_958441
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GQKTKV 6
           GQKTK+
Sbjct: 485 GQKTKI 490





>NP_958439
          Length = 628

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GQKTKV 6
           GQKTK+
Sbjct: 485 GQKTKI 490





>NP_005219
          Length = 1210

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GQKTKV 6
           GQKTK+
Sbjct: 485 GQKTKI 490





>NP_001699
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QKTKVST 8
           QKT+VST
Sbjct: 333 QKTEVST 339





>NP_001185744
          Length = 1773

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 204 EATKVSTT 211






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 953 ETTKVSTT 960





>XP_005275558
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>XP_005275391
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>XP_005275259
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>XP_005274965
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>XP_005272815
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>XP_005274885
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>XP_005248836
          Length = 1776

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 207 EATKVSTT 214






 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKTKVSTT 9
           + TKVSTT
Sbjct: 956 ETTKVSTT 963





>NP_001136061
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 125 GQQTTSSTT 133





>NP_001136060
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>NP_001136059
          Length = 334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>NP_001136062
          Length = 301

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>NP_055038
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>XP_006710725
          Length = 421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 249 GQQTTSSTT 257





>XP_005270953
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>XP_006710724
          Length = 439

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>XP_006710723
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 249 GQQTTSSTT 257





>XP_005270951
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>XP_005270950
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 163 GQQTTSSTT 171





>XP_005270948
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 183 GQQTTSSTT 191





>XP_006710722
          Length = 487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 192 GQQTTSSTT 200





>XP_006710721
          Length = 525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 249 GQQTTSSTT 257





>XP_006710720
          Length = 528

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 233 GQQTTSSTT 241





>XP_006710719
          Length = 537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 242 GQQTTSSTT 250





>XP_005270952
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GQKTKVSTT 9
           GQ+T  STT
Sbjct: 249 GQQTTSSTT 257





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.289    0.103    0.247 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 383,900
Number of extensions: 424
Number of successful extensions: 53
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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