Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              20     509
XP_006715292                                                           20     509
NP_775771                                                              19     665
NP_660204                                                              19     665
XP_006720466                                                           19     665
XP_005254230                                                           19     665
XP_006720465                                                           19     665
XP_005254228                                                           19     665
NP_001885                                                              18    1935
NP_689407                                                              18    1935
NP_001276841                                                           18    1935
NP_001020276                                                           18    1935
NP_001258671                                                           18    1935
NP_001258670                                                           18    1935
NP_001883                                                              18    1935
NP_001884                                                              18    1935
NP_620693                                                              18    1935
XP_005256394                                                           18    1935
XP_005256393                                                           18    1935
NP_002370                                                              16    5631
NP_071331                                                              16    7355
NP_001038188                                                           16    7355
NP_004375                                                              16    7355
NP_001257501                                                           16    7355
NP_005449                                                              16    7355
NP_001257502                                                           16    7355
NP_001257503                                                           16    7355
NP_001026982                                                           16    7355
NP_001310                                                              16    7355
XP_005259559                                                           16    7355
XP_005259558                                                           16    7355
XP_005259557                                                           16    7355
XP_005259556                                                           16    7355
XP_005259555                                                           16    7355
XP_005252373                                                           16    7355
XP_005271953                                                           16    7355
XP_005271952                                                           16    7355
XP_005271951                                                           16    7355
XP_005271950                                                           16    7355
XP_005271949                                                           16    7355
XP_005271948                                                           16    7355
NP_001239268                                                           15    9605
NP_001239267                                                           15    9605
NP_001785                                                              15    9605
NP_055455                                                              15    9605
XP_005247035                                                           15    9605
XP_006712939                                                           15    9605
XP_006712938                                                           15    9605
XP_006712937                                                           15    9605
XP_006712936                                                           15    9605
XP_005247034                                                           15    9605
NP_997046                                                              15    9605
>NP_115927
          Length = 1321

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYASVN
Sbjct: 201 GTVRYASVN 209
>XP_006715292
          Length = 759

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYASVN
Sbjct: 188 GTVRYASVN 196
>NP_775771
          Length = 1244

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYAS+N
Sbjct: 188 GTVRYASIN 196
>NP_660204
          Length = 337

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYAS+N
Sbjct: 183 GTVRYASIN 191
>XP_006720466
          Length = 1175

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYAS+N
Sbjct: 119 GTVRYASIN 127
>XP_005254230
          Length = 1175

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYAS+N
Sbjct: 119 GTVRYASIN 127
>XP_006720465
          Length = 1239

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYAS+N
Sbjct: 183 GTVRYASIN 191
>XP_005254228
          Length = 1250

 Score = 19.2 bits (38), Expect =   665
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GMVRYASVN 9
           G VRYAS+N
Sbjct: 194 GTVRYASIN 202
>NP_001885
          Length = 416

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>NP_689407
          Length = 416

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>NP_001276841
          Length = 416

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>NP_001020276
          Length = 365

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 211 GTARYASIN 219
>NP_001258671
          Length = 276

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 122 GTARYASIN 130
>NP_001258670
          Length = 325

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 183 GTARYASIN 191
>NP_001883
          Length = 337

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 183 GTARYASIN 191
>NP_001884
          Length = 415

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>NP_620693
          Length = 409

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>XP_005256394
          Length = 427

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>XP_005256393
          Length = 450

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GMVRYASVN 9
           G  RYAS+N
Sbjct: 175 GTARYASIN 183
>NP_002370
          Length = 496

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GMVRYAS 7
          GMV YAS
Sbjct: 81 GMVNYAS 87
>NP_071331
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 213 GTARYMSIN 221
>NP_001038188
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>NP_004375
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>NP_001257501
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>NP_005449
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GMVRYASV 8
           GM+ YAS+
Sbjct: 527 GMLSYASI 534
>NP_001257502
          Length = 348

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 136 GTARYMSIN 144
>NP_001257503
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 98  GTARYMSIN 106
>NP_001026982
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>NP_001310
          Length = 415

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 214 GTARYMSIN 222
>XP_005259559
          Length = 367

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 166 GTARYMSIN 174
>XP_005259558
          Length = 392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 166 GTARYMSIN 174
>XP_005259557
          Length = 440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 214 GTARYMSIN 222
>XP_005259556
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 244 GTARYMSIN 252
>XP_005259555
          Length = 445

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 244 GTARYMSIN 252
>XP_005252373
          Length = 683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GMVRYASV 8
           GM+ YAS+
Sbjct: 269 GMLSYASI 276
>XP_005271953
          Length = 416

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>XP_005271952
          Length = 424

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>XP_005271951
          Length = 447

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>XP_005271950
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>XP_005271949
          Length = 455

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>XP_005271948
          Length = 456

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G  RY S+N
Sbjct: 211 GTARYMSIN 219
>NP_001239268
          Length = 842

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GMVRYASV 8
           GMVRY  V
Sbjct: 238 GMVRYRIV 245
>NP_001239267
          Length = 879

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GMVRYASV 8
           GMVRY  V
Sbjct: 275 GMVRYRIV 282
>NP_001785
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GMVRYASV 8
           GMVRY  V
Sbjct: 312 GMVRYRIV 319
>NP_055455
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>XP_005247035
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>XP_006712939
          Length = 972

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>XP_006712938
          Length = 1138

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>XP_006712937
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>XP_006712936
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>XP_005247034
          Length = 1199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GMVRYAS 7
           G+VR+AS
Sbjct: 785 GLVRFAS 791
>NP_997046
          Length = 547

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GMVRYASVN 9
           G V Y SVN
Sbjct: 149 GTVNYDSVN 157
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.130    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,669
Number of extensions: 659
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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