Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     509
NP_002600                                                              20     509
XP_005268521                                                           20     509
XP_005265800                                                           20     509
XP_006714103                                                           20     509
XP_006714102                                                           20     509
NP_001167535                                                           18    1135
NP_001167534                                                           18    1135
NP_001167536                                                           18    1135
NP_001167537                                                           18    1135
NP_002011                                                              18    1135
NP_891555                                                              18    1135
NP_056934                                                              18    1135
NP_075598                                                              18    1135
NP_075594                                                              18    1135
NP_075593                                                              18    1135
NP_002244                                                              18    1135
NP_001167538                                                           18    1135
XP_006716377                                                           18    1135
XP_006716376                                                           18    1135
XP_006716375                                                           18    1135
XP_006716374                                                           18    1135
XP_006716373                                                           18    1135
XP_006716372                                                           18    1135
XP_006716371                                                           18    1135
XP_006716370                                                           18    1135
XP_006716369                                                           18    1135
XP_006716368                                                           18    1135
XP_006716367                                                           18    1135
XP_006716366                                                           18    1135
NP_002010                                                              17    2528
NP_000236                                                              17    3301
NP_001138389                                                           17    3301
NP_001138390                                                           17    3301
NP_001120972                                                           17    3301
NP_001138386                                                           17    3301
NP_001138387                                                           17    3301
NP_000132                                                              17    3301
NP_075259                                                              17    3301
NP_001138388                                                           17    3301
NP_001138391                                                           17    3301
NP_001138385                                                           17    3301
NP_075418                                                              17    3301
NP_001156685                                                           17    3301
NP_000133                                                              17    3301
NP_075254                                                              17    3301
XP_006717776                                                           17    3301
XP_006717775                                                           17    3301
XP_006717774                                                           17    3301
XP_006717773                                                           17    3301
XP_006717772                                                           17    3301
XP_006717771                                                           17    3301
XP_006716054                                                           17    3301
XP_006716053                                                           17    3301
XP_006716052                                                           17    3301
XP_006716051                                                           17    3301
XP_006713936                                                           17    3301
XP_006713935                                                           17    3301
XP_006713934                                                           17    3301
XP_006713933                                                           17    3301
XP_006713932                                                           17    3301
XP_006713931                                                           17    3301
NP_001278253                                                           17    4312
XP_006722052                                                           17    4312
NP_004165                                                              16    5631
NP_001271280                                                           16    5631
NP_002438                                                              15    9605
NP_001231866                                                           15    9605
XP_005265227                                                           15    9605
NP_660347                                                              15    9605
>NP_006197
          Length = 1089

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GMEFLASK
Sbjct: 805 GMEFLASK 812
>NP_002600
          Length = 1106

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GMEFLASK
Sbjct: 813 GMEFLASK 820
>XP_005268521
          Length = 1042

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GMEFLASK
Sbjct: 749 GMEFLASK 756
>XP_005265800
          Length = 1089

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GMEFLASK
Sbjct: 805 GMEFLASK 812
>XP_006714103
          Length = 1111

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GMEFLASK
Sbjct: 827 GMEFLASK 834
>XP_006714102
          Length = 1114

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GMEFLASK
Sbjct: 830 GMEFLASK 837
>NP_001167535
          Length = 812

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 600 GMEYLASK 607
>NP_001167534
          Length = 820

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 608 GMEYLASK 615
>NP_001167536
          Length = 820

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 608 GMEYLASK 615
>NP_001167537
          Length = 733

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 521 GMEYLASK 528
>NP_002011
          Length = 1298

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GMEFLAS+
Sbjct: 1024 GMEFLASR 1031
>NP_891555
          Length = 1363

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GMEFLAS+
Sbjct: 1024 GMEFLASR 1031
>NP_056934
          Length = 820

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 608 GMEYLASK 615
>NP_075598
          Length = 822

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 610 GMEYLASK 617
>NP_075594
          Length = 731

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 519 GMEYLASK 526
>NP_075593
          Length = 733

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 521 GMEYLASK 528
>NP_002244
          Length = 1356

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GMEFLAS+
Sbjct: 1015 GMEFLASR 1022
>NP_001167538
          Length = 853

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 641 GMEYLASK 648
>XP_006716377
          Length = 741

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 519 GMEYLASK 526
>XP_006716376
          Length = 741

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 519 GMEYLASK 526
>XP_006716375
          Length = 743

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 521 GMEYLASK 528
>XP_006716374
          Length = 743

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 521 GMEYLASK 528
>XP_006716373
          Length = 743

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 521 GMEYLASK 528
>XP_006716372
          Length = 824

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 602 GMEYLASK 609
>XP_006716371
          Length = 830

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 608 GMEYLASK 615
>XP_006716370
          Length = 830

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 608 GMEYLASK 615
>XP_006716369
          Length = 830

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 608 GMEYLASK 615
>XP_006716368
          Length = 832

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 610 GMEYLASK 617
>XP_006716367
          Length = 832

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 610 GMEYLASK 617
>XP_006716366
          Length = 832

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LASK
Sbjct: 610 GMEYLASK 617
>NP_002010
          Length = 1338

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GMEFL+S+
Sbjct: 1009 GMEFLSSR 1016
>NP_000236
          Length = 1390

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GM++LASK
Sbjct: 1191 GMKYLASK 1198
>NP_001138389
          Length = 705

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 497 GMEYLASQ 504
>NP_001138390
          Length = 704

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 496 GMEYLASQ 503
>NP_001120972
          Length = 1408

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GM++LASK
Sbjct: 1209 GMKYLASK 1216
>NP_001138386
          Length = 709

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 501 GMEYLASQ 508
>NP_001138387
          Length = 707

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 524 GMEYLASQ 531
>NP_000132
          Length = 821

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 613 GMEYLASQ 620
>NP_075259
          Length = 822

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 614 GMEYLASQ 621
>NP_001138388
          Length = 706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 498 GMEYLASQ 505
>NP_001138391
          Length = 680

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 525 GMEYLASQ 532
>NP_001138385
          Length = 769

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 614 GMEYLASQ 621
>NP_075418
          Length = 732

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 524 GMEYLASQ 531
>NP_001156685
          Length = 808

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 606 GMEYLASQ 613
>NP_000133
          Length = 806

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 604 GMEYLASQ 611
>NP_075254
          Length = 694

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 492 GMEYLASQ 499
>XP_006717776
          Length = 806

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 632 GMEYLASQ 639
>XP_006717775
          Length = 726

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 518 GMEYLASQ 525
>XP_006717774
          Length = 752

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 544 GMEYLASQ 551
>XP_006717773
          Length = 807

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 633 GMEYLASQ 640
>XP_006717772
          Length = 838

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 630 GMEYLASQ 637
>XP_006717771
          Length = 839

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 631 GMEYLASQ 638
>XP_006716054
          Length = 960

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GM++LASK
Sbjct: 761 GMKYLASK 768
>XP_006716053
          Length = 960

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GM++LASK
Sbjct: 761 GMKYLASK 768
>XP_006716052
          Length = 1409

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GM++LASK
Sbjct: 1210 GMKYLASK 1217
>XP_006716051
          Length = 1427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    GMEFLASK 8
            GM++LASK
Sbjct: 1228 GMKYLASK 1235
>XP_006713936
          Length = 807

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 604 GMEYLASQ 611
>XP_006713935
          Length = 807

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 605 GMEYLASQ 612
>XP_006713934
          Length = 809

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 606 GMEYLASQ 613
>XP_006713933
          Length = 810

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 607 GMEYLASQ 614
>XP_006713932
          Length = 810

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 608 GMEYLASQ 615
>XP_006713931
          Length = 811

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GMEFLASK 8
           GME+LAS+
Sbjct: 608 GMEYLASQ 615
>NP_001278253
          Length = 2639

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    GMEFLAS 7
            G+EFLAS
Sbjct: 1065 GLEFLAS 1071
>XP_006722052
          Length = 2631

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    GMEFLAS 7
            G+EFLAS
Sbjct: 1065 GLEFLAS 1071
>NP_004165
          Length = 834

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GMEFLAS 7
           G+EFLAS
Sbjct: 733 GIEFLAS 739
>NP_001271280
          Length = 825

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GMEFLAS 7
           G+EFLAS
Sbjct: 724 GIEFLAS 730
>NP_002438
          Length = 1400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GMEFLASK 8
            GME+LA +
Sbjct: 1195 GMEYLAEQ 1202
>NP_001231866
          Length = 1351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GMEFLASK 8
            GME+LA +
Sbjct: 1146 GMEYLAEQ 1153
>XP_005265227
          Length = 1401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GMEFLASK 8
            GME+LA +
Sbjct: 1196 GMEYLAEQ 1203
>NP_660347
          Length = 177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  GMEFLA 6
          GMEF+A
Sbjct: 79 GMEFIA 84
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.139    0.363 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 289,552
Number of extensions: 556
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package