Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_899236                                                              15    9605
NP_056363                                                              15    9605
NP_001138241                                                           15    9605
NP_001138242                                                           15    9605
NP_004037                                                              15    9605
NP_001001937                                                           15    9605
NP_001398                                                              15    9605
NP_001244263                                                           15    9605
XP_006715232                                                           15    9605
XP_005249382                                                           15    9605
XP_005249381                                                           15    9605
XP_005249380                                                           15    9605
XP_005249379                                                           15    9605
XP_005249377                                                           15    9605
XP_005249376                                                           15    9605
XP_005249375                                                           15    9605
XP_005249374                                                           15    9605
XP_005249373                                                           15    9605
XP_005249372                                                           15    9605
XP_005249371                                                           15    9605
XP_005249370                                                           15    9605
XP_005249369                                                           15    9605
XP_005249368                                                           15    9605
XP_005249367                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GLVSKNVMA 9
            GLVSK+VMA
Sbjct: 1928 GLVSKDVMA 1936
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GLVSKNVMA 9
            GLVSK+VMA
Sbjct: 1723 GLVSKDVMA 1731
>NP_899236
          Length = 5497

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 2110 IISKNIM 2116
>NP_056363
          Length = 5171

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 1784 IISKNIM 1790
>NP_001138241
          Length = 5675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 2288 IISKNIM 2294
>NP_001138242
          Length = 5537

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 2150 IISKNIM 2156
>NP_004037
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GLVSKNVM 8
          GLVS+N +
Sbjct: 19 GLVSRNAL 26
>NP_001001937
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GLVSKNVM 8
          GLVS+N +
Sbjct: 19 GLVSRNAL 26
>NP_001398
          Length = 3312

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GLVSKNVM 8
            GLV+ N+M
Sbjct: 2318 GLVTPNIM 2325
>NP_001244263
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GLVSKNVM 8
          GLVS+N +
Sbjct: 19 GLVSRNAL 26
>XP_006715232
          Length = 7498

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4196 IISKNIM 4202
>XP_005249382
          Length = 5732

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 2321 IISKNIM 2327
>XP_005249381
          Length = 7281

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 3870 IISKNIM 3876
>XP_005249380
          Length = 7607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4196 IISKNIM 4202
>XP_005249379
          Length = 7633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4222 IISKNIM 4228
>XP_005249377
          Length = 7640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4229 IISKNIM 4235
>XP_005249376
          Length = 7647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4236 IISKNIM 4242
>XP_005249375
          Length = 7680

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4269 IISKNIM 4275
>XP_005249374
          Length = 7709

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249373
          Length = 7723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4312 IISKNIM 4318
>XP_005249372
          Length = 7785

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4374 IISKNIM 4380
>XP_005249371
          Length = 7788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249370
          Length = 7794

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249369
          Length = 7797

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4386 IISKNIM 4392
>XP_005249368
          Length = 7812

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
>XP_005249367
          Length = 7818

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 2    LVSKNVM 8
            ++SKN+M
Sbjct: 4407 IISKNIM 4413
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.126    0.314 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 338,787
Number of extensions: 395
Number of successful extensions: 26
Number of sequences better than 10000.0: 26
Number of HSP's gapped: 26
Number of HSP's successfully gapped: 26
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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