Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005124                                                              18    1482
NP_055726                                                              18    1935
NP_001265105                                                           17    3301
XP_005266918                                                           17    4312
NP_689646                                                              16    5631
NP_940841                                                              16    5631
XP_006718830                                                           16    5631
NP_001866                                                              16    7355
NP_542410                                                              16    7355
NP_542411                                                              16    7355
NP_542412                                                              16    7355
NP_055664                                                              16    7355
NP_004925                                                              16    7355
NP_001004339                                                           16    7355
NP_001161139                                                           16    7355
NP_001116105                                                           16    7355
NP_689854                                                              16    7355
NP_001269588                                                           16    7355
NP_060414                                                              16    7355
XP_006719336                                                           16    7355
XP_006719335                                                           16    7355
XP_005253054                                                           16    7355
XP_006714500                                                           16    7355
XP_006714499                                                           16    7355
XP_006714498                                                           16    7355
XP_005248285                                                           16    7355
NP_001166896                                                           15    9605
NP_056219                                                              15    9605
NP_116228                                                              15    9605
NP_005867                                                              15    9605
XP_006717104                                                           15    9605
XP_005251954                                                           15    9605
XP_005251952                                                           15    9605
XP_006712256                                                           15    9605
XP_005246298                                                           15    9605
XP_005246297                                                           15    9605
XP_005246299                                                           15    9605
XP_006712255                                                           15    9605
XP_005246296                                                           15    9605
XP_006712254                                                           15    9605
XP_005246295                                                           15    9605
XP_006712253                                                           15    9605
XP_006712252                                                           15    9605
XP_005246294                                                           15    9605
XP_006712251                                                           15    9605
XP_005246293                                                           15    9605
XP_005246292                                                           15    9605
XP_006712250                                                           15    9605
>NP_005124
          Length = 329

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  GLRLLSVS 8
          GLRLLSVS
Sbjct: 8  GLRLLSVS 15
>NP_055726
          Length = 961

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           GL LLSVSD
Sbjct: 769 GLPLLSVSD 777
>NP_001265105
          Length = 768

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  GLRLLSVSD 9
          GL+LLS SD
Sbjct: 24 GLKLLSSSD 32
>XP_005266918
          Length = 1298

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   GLRLLSV 7
           GLRLLSV
Sbjct: 855 GLRLLSV 861
>NP_689646
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LRLLSVSD 9
           L+LLS+SD
Sbjct: 155 LQLLSISD 162
>NP_940841
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LRLLSVSD 9
           L+LLS+SD
Sbjct: 155 LQLLSISD 162
>XP_006718830
          Length = 612

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   LRLLSVSD 9
           L+LLS+SD
Sbjct: 155 LQLLSISD 162
>NP_001866
          Length = 1500

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GLRLLSV 7
          G+RLLSV
Sbjct: 35 GIRLLSV 41
>NP_542410
          Length = 1629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    LRLLSVS 8
            LRLLSVS
Sbjct: 1533 LRLLSVS 1539
>NP_542411
          Length = 1736

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    LRLLSVS 8
            LRLLSVS
Sbjct: 1640 LRLLSVS 1646
>NP_542412
          Length = 1650

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    LRLLSVS 8
            LRLLSVS
Sbjct: 1554 LRLLSVS 1560
>NP_055664
          Length = 742

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GLRLLSVS 8
           GLRL SVS
Sbjct: 518 GLRLKSVS 525
>NP_004925
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           G+R+L V+D
Sbjct: 475 GIRVLDVND 483
>NP_001004339
          Length = 759

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GLRLLSV 7
           GLR+LSV
Sbjct: 182 GLRILSV 188
>NP_001161139
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           G+R+L V+D
Sbjct: 475 GIRVLDVND 483
>NP_001116105
          Length = 1506

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GLRLLSV 7
          G+RLLSV
Sbjct: 41 GIRLLSV 47
>NP_689854
          Length = 1835

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GLRLLSVSD 9
            G+R++++SD
Sbjct: 1535 GVRIVTISD 1543
>NP_001269588
          Length = 1355

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LRLLSVS 8
           LRLLSVS
Sbjct: 751 LRLLSVS 757
>NP_060414
          Length = 1287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LRLLSVS 8
           LRLLSVS
Sbjct: 683 LRLLSVS 689
>XP_006719336
          Length = 1779

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GLRLLSVSD 9
            G+R++++SD
Sbjct: 1479 GVRIVTISD 1487
>XP_006719335
          Length = 1793

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GLRLLSVSD 9
            G+R++++SD
Sbjct: 1535 GVRIVTISD 1543
>XP_005253054
          Length = 1375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LRLLSVS 8
           LRLLSVS
Sbjct: 771 LRLLSVS 777
>XP_006714500
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           G+R+L V+D
Sbjct: 475 GIRVLDVND 483
>XP_006714499
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           G+R+L V+D
Sbjct: 475 GIRVLDVND 483
>XP_006714498
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           G+R+L V+D
Sbjct: 475 GIRVLDVND 483
>XP_005248285
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLRLLSVSD 9
           G+R+L V+D
Sbjct: 475 GIRVLDVND 483
>NP_001166896
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLRLLSVS 8
          GLRLLS +
Sbjct: 31 GLRLLSAN 38
>NP_056219
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLRLLSVS 8
          GLRLLS +
Sbjct: 31 GLRLLSAN 38
>NP_116228
          Length = 478

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLRLLSVSD 9
           GLR + +SD
Sbjct: 132 GLRCIPISD 140
>NP_005867
          Length = 3267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2348 GLRLLSRS 2355
>XP_006717104
          Length = 574

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLRLLSVS 8
          GLRLLS +
Sbjct: 31 GLRLLSAN 38
>XP_005251954
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLRLLSVS 8
          GLRLLS +
Sbjct: 31 GLRLLSAN 38
>XP_005251952
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLRLLSVS 8
          GLRLLS +
Sbjct: 31 GLRLLSAN 38
>XP_006712256
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 1499 GLRLLSRS 1506
>XP_005246298
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 1499 GLRLLSRS 1506
>XP_005246297
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 1499 GLRLLSRS 1506
>XP_005246299
          Length = 2480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 1561 GLRLLSRS 1568
>XP_006712255
          Length = 2622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2348 GLRLLSRS 2355
>XP_005246296
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 1556 GLRLLSRS 1563
>XP_006712254
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 1556 GLRLLSRS 1563
>XP_005246295
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2195 GLRLLSRS 2202
>XP_006712253
          Length = 3117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2198 GLRLLSRS 2205
>XP_006712252
          Length = 3163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2244 GLRLLSRS 2251
>XP_005246294
          Length = 3173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2254 GLRLLSRS 2261
>XP_006712251
          Length = 3176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2257 GLRLLSRS 2264
>XP_005246293
          Length = 3206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2287 GLRLLSRS 2294
>XP_005246292
          Length = 3208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2289 GLRLLSRS 2296
>XP_006712250
          Length = 3248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1    GLRLLSVS 8
            GLRLLS S
Sbjct: 2329 GLRLLSRS 2336
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.142    0.361 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 343,820
Number of extensions: 497
Number of successful extensions: 48
Number of sequences better than 10000.0: 48
Number of HSP's gapped: 48
Number of HSP's successfully gapped: 48
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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