Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              20     390
NP_671714                                                              20     390
XP_006715890                                                           20     390
XP_005250160                                                           20     390
XP_005250159                                                           20     390
NP_115991                                                              18    1482
NP_000319                                                              17    4312
XP_005272690                                                           17    4312
XP_006724601                                                           17    4312
NP_001278413                                                           16    5631
NP_004354                                                              16    5631
NP_689799                                                              16    5631
XP_005258470                                                           16    5631
XP_006721057                                                           16    5631
XP_006717717                                                           16    5631
XP_005269639                                                           16    5631
XP_006717716                                                           16    5631
XP_006717715                                                           16    5631
XP_006717714                                                           16    5631
XP_006717713                                                           16    5631
XP_006717712                                                           16    5631
XP_006717711                                                           16    5631
XP_005269635                                                           16    5631
XP_006717710                                                           16    5631
XP_006717709                                                           16    5631
XP_006717708                                                           16    5631
NP_776191                                                              16    7355
NP_001258782                                                           16    7355
NP_066267                                                              16    7355
NP_001258781                                                           16    7355
XP_006717852                                                           16    7355
XP_006717851                                                           16    7355
XP_006717850                                                           16    7355
XP_006717849                                                           16    7355
XP_006717848                                                           16    7355
XP_006717847                                                           16    7355
XP_006717846                                                           16    7355
XP_006717845                                                           16    7355
XP_006715525                                                           16    7355
XP_006715524                                                           16    7355
XP_005266995                                                           16    7355
XP_005266994                                                           16    7355
XP_005266993                                                           16    7355
XP_005266992                                                           16    7355
NP_001077004                                                           16    7355
NP_055660                                                              15    9605
NP_112224                                                              15    9605
NP_000103                                                              15    9605
NP_077270                                                              15    9605
NP_596870                                                              15    9605
NP_542194                                                              15    9605
NP_073595                                                              15    9605
NP_055510                                                              15    9605
NP_954650                                                              15    9605
NP_001003396                                                           15    9605
NP_001137452                                                           15    9605
NP_008940                                                              15    9605
NP_001153350                                                           15    9605
XP_005256934                                                           15    9605
XP_006721670                                                           15    9605
XP_005253212                                                           15    9605
XP_005253211                                                           15    9605
XP_006715685                                                           15    9605
XP_005267181                                                           15    9605
XP_006715621                                                           15    9605
XP_006715620                                                           15    9605
XP_005267180                                                           15    9605
XP_005267179                                                           15    9605
XP_006715619                                                           15    9605
XP_005267178                                                           15    9605
XP_005249355                                                           15    9605
NP_001003397                                                           15    9605
NP_001003395                                                           15    9605
NP_003278                                                              15    9605
>NP_005742
          Length = 3907

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GLQNEMSQ 8
           GLQNEMSQ
Sbjct: 669 GLQNEMSQ 676
>NP_671714
          Length = 3899

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GLQNEMSQ 8
           GLQNEMSQ
Sbjct: 669 GLQNEMSQ 676
>XP_006715890
          Length = 3860

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GLQNEMSQ 8
           GLQNEMSQ
Sbjct: 669 GLQNEMSQ 676
>XP_005250160
          Length = 3939

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GLQNEMSQ 8
           GLQNEMSQ
Sbjct: 669 GLQNEMSQ 676
>XP_005250159
          Length = 3952

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   GLQNEMSQ 8
           GLQNEMSQ
Sbjct: 669 GLQNEMSQ 676
>NP_115991
          Length = 543

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GLQNEMSQN 9
           GLQN MSQ+
Sbjct: 359 GLQNTMSQS 367
>NP_000319
          Length = 815

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QNEMSQN 9
           QN MSQN
Sbjct: 790 QNHMSQN 796
>XP_005272690
          Length = 704

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   QNEMSQN 9
           QN MSQN
Sbjct: 679 QNHMSQN 685
>XP_006724601
          Length = 1020

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3    QNEMSQN 9
            QN MSQN
Sbjct: 995  QNHMSQN 1001
>NP_001278413
          Length = 702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLQNEMS 7
           G+QNE+S
Sbjct: 394 GIQNELS 400
>NP_004354
          Length = 702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLQNEMS 7
           G+QNE+S
Sbjct: 394 GIQNELS 400
>NP_689799
          Length = 1684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_005258470
          Length = 524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLQNEMS 7
           G+QNE+S
Sbjct: 394 GIQNELS 400
>XP_006721057
          Length = 257

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLQNEMSQN 9
           GLQ ++S+N
Sbjct: 182 GLQEQLSRN 190
>XP_006717717
          Length = 859

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_005269639
          Length = 1580

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717716
          Length = 1619

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717715
          Length = 1660

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717714
          Length = 1665

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717713
          Length = 1666

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717712
          Length = 1670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717711
          Length = 1677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_005269635
          Length = 1695

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717710
          Length = 1706

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717709
          Length = 1712

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>XP_006717708
          Length = 1717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  GLQNEMSQN 9
          GL NE  QN
Sbjct: 32 GLSNEPGQN 40
>NP_776191
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 27 QNEPSQN 33
>NP_001258782
          Length = 391

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 27 QNEPSQN 33
>NP_066267
          Length = 4377

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3379 QNEIAQN 3385
>NP_001258781
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 27 QNEPSQN 33
>XP_006717852
          Length = 3508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 2510 QNEIAQN 2516
>XP_006717851
          Length = 3513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 2515 QNEIAQN 2521
>XP_006717850
          Length = 4364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3366 QNEIAQN 3372
>XP_006717849
          Length = 4383

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3385 QNEIAQN 3391
>XP_006717848
          Length = 4392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3394 QNEIAQN 3400
>XP_006717847
          Length = 4395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3397 QNEIAQN 3403
>XP_006717846
          Length = 4396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3398 QNEIAQN 3404
>XP_006717845
          Length = 4397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    QNEMSQN 9
            QNE++QN
Sbjct: 3399 QNEIAQN 3405
>XP_006715525
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 27 QNEPSQN 33
>XP_006715524
          Length = 477

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 27 QNEPSQN 33
>XP_005266995
          Length = 498

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 65 QNEPSQN 71
>XP_005266994
          Length = 499

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 65 QNEPSQN 71
>XP_005266993
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 65 QNEPSQN 71
>XP_005266992
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 65 QNEPSQN 71
>NP_001077004
          Length = 460

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  QNEMSQN 9
          QNE SQN
Sbjct: 27 QNEPSQN 33
>NP_055660
          Length = 907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   LQNEMSQN 9
           L++EM+QN
Sbjct: 189 LKSEMTQN 196
>NP_112224
          Length = 1849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   LQNEMSQN 9
           +QN++ QN
Sbjct: 958 MQNQLQQN 965
>NP_000103
          Length = 739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLQNEMS 7
           G+Q+EMS
Sbjct: 630 GIQDEMS 636
>NP_077270
          Length = 298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QNEMSQN 9
           QN +SQN
Sbjct: 261 QNRLSQN 267
>NP_596870
          Length = 5604

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2    LQNEMSQN 9
            L N+M QN
Sbjct: 3776 LSNQMDQN 3783
>NP_542194
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GLQNEMSQ 8
           GLQ ++SQ
Sbjct: 836 GLQEQLSQ 843
>NP_073595
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QNEMSQN 9
           QN +SQN
Sbjct: 195 QNRLSQN 201
>NP_055510
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LQNEMSQ 8
           LQNE+S+
Sbjct: 673 LQNELSE 679
>NP_954650
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GLQNEMSQ 8
           GLQ ++SQ
Sbjct: 598 GLQEQLSQ 605
>NP_001003396
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
>NP_001137452
          Length = 667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GLQNEM 6
           GLQN+M
Sbjct: 141 GLQNQM 146
>NP_008940
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GLQNEM 6
           GLQNE+
Sbjct: 225 GLQNEL 230
>NP_001153350
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GLQNEM 6
           GLQNE+
Sbjct: 224 GLQNEL 229
>XP_005256934
          Length = 1434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LQNEMSQ 8
           LQNE+S+
Sbjct: 673 LQNELSE 679
>XP_006721670
          Length = 1471

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LQNEMSQ 8
           LQNE+S+
Sbjct: 673 LQNELSE 679
>XP_005253212
          Length = 1838

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   LQNEMSQN 9
           +QN++ QN
Sbjct: 915 MQNQLQQN 922
>XP_005253211
          Length = 1881

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   LQNEMSQN 9
           +QN++ QN
Sbjct: 958 MQNQLQQN 965
>XP_006715685
          Length = 761

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  LQNEMSQN 9
          L++EM+QN
Sbjct: 43 LKSEMTQN 50
>XP_005267181
          Length = 102

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 46 LMNELKQN 53
>XP_006715621
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
>XP_006715620
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
>XP_005267180
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 46 LMNELKQN 53
>XP_005267179
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 46 LMNELKQN 53
>XP_006715619
          Length = 176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
>XP_005267178
          Length = 191

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
>XP_005249355
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   QNEMSQN 9
           QN +SQN
Sbjct: 261 QNRLSQN 267
>NP_001003397
          Length = 131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
>NP_001003395
          Length = 175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 46 LMNELKQN 53
>NP_003278
          Length = 204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2  LQNEMSQN 9
          L NE+ QN
Sbjct: 75 LMNELKQN 82
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.113    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 450,578
Number of extensions: 858
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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