Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115803                                                              20     509
NP_079039                                                              17    2528
NP_996897                                                              17    2528
NP_001123488                                                           17    2528
NP_001123489                                                           17    2528
NP_001170                                                              17    2528
XP_005263062                                                           17    2528
XP_005263061                                                           17    2528
XP_005263060                                                           17    2528
XP_005263059                                                           17    2528
XP_006714283                                                           17    2528
XP_005263056                                                           17    2528
XP_006714282                                                           17    2528
XP_006714281                                                           17    2528
XP_005263054                                                           17    2528
XP_005271269                                                           17    2528
NP_001159579                                                           17    3301
NP_005509                                                              17    3301
NP_001910                                                              17    3301
NP_001008781                                                           16    5631
NP_006539                                                              16    7355
NP_001095939                                                           16    7355
NP_001137505                                                           16    7355
XP_006720705                                                           16    7355
XP_005270106                                                           16    7355
XP_006713540                                                           16    7355
NP_660329                                                              16    7355
NP_001094874                                                           16    7355
NP_001077                                                              15    9605
NP_001600                                                              15    9605
NP_002290                                                              15    9605
NP_055481                                                              15    9605
NP_065801                                                              15    9605
NP_001182485                                                           15    9605
NP_001182484                                                           15    9605
XP_005247161                                                           15    9605
XP_005247160                                                           15    9605
>NP_115803
          Length = 1156

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GLNQSRMGI 9
            GLNQSR GI
Sbjct: 1068 GLNQSRTGI 1076
>NP_079039
          Length = 848

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GLNQSRMGI 9
          G NQSRM +
Sbjct: 83 GANQSRMAV 91
>NP_996897
          Length = 545

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GLNQSRMGI 9
          G NQSRM +
Sbjct: 83 GANQSRMAV 91
>NP_001123488
          Length = 389

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>NP_001123489
          Length = 367

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>NP_001170
          Length = 378

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263062
          Length = 353

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263061
          Length = 356

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263060
          Length = 357

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263059
          Length = 363

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_006714283
          Length = 368

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263056
          Length = 378

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_006714282
          Length = 379

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_006714281
          Length = 390

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005263054
          Length = 400

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLNQSRMG 8
           GLNQ+R G
Sbjct: 174 GLNQARFG 181
>XP_005271269
          Length = 783

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GLNQSRMGI 9
          G NQSRM +
Sbjct: 83 GANQSRMAV 91
>NP_001159579
          Length = 466

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLNQSRMG 8
          GL Q+RMG
Sbjct: 87 GLGQTRMG 94
>NP_005509
          Length = 508

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GLNQSRMG 8
          GL Q+RMG
Sbjct: 87 GLGQTRMG 94
>NP_001910
          Length = 302

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GLNQSRMGI 9
           GLN++++GI
Sbjct: 175 GLNETQLGI 183
>NP_001008781
          Length = 4557

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  NQSRMGI 9
          +QSRMGI
Sbjct: 64 SQSRMGI 70
>NP_006539
          Length = 599

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GLNQSRMGI 9
           GLN S +GI
Sbjct: 365 GLNLSALGI 373
>NP_001095939
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNQSRMGI 9
           +NQSRM +
Sbjct: 271 MNQSRMDV 278
>NP_001137505
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  GLNQSRMGI 9
          G+N  R+G+
Sbjct: 9  GVNNKRLGV 17
>XP_006720705
          Length = 508

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LNQSRMGI 9
           +NQ+R+G+
Sbjct: 306 MNQARLGL 313
>XP_005270106
          Length = 398

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNQSRMGI 9
           +NQSRM +
Sbjct: 271 MNQSRMDV 278
>XP_006713540
          Length = 343

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GLNQSRMGI 9
           GLN S +GI
Sbjct: 109 GLNLSALGI 117
>NP_660329
          Length = 291

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1  GLNQSRMGI 9
          G+N  R+G+
Sbjct: 18 GVNNKRLGV 26
>NP_001094874
          Length = 451

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LNQSRMGI 9
           +NQ+R+G+
Sbjct: 249 MNQARLGL 256
>NP_001077
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLNQSRMGI 9
           G+N  R+GI
Sbjct: 177 GVNPERIGI 185
>NP_001600
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNQSRMGI 9
           LN+ R+GI
Sbjct: 290 LNEGRIGI 297
>NP_002290
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GLNQSRM 7
            GLN+SR+
Sbjct: 1654 GLNKSRL 1660
>NP_055481
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNQSRMGI 9
           +NQS MG+
Sbjct: 572 MNQSMMGM 579
>NP_065801
          Length = 1204

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLNQSRM 7
           GLN++RM
Sbjct: 715 GLNRARM 721
>NP_001182485
          Length = 625

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNQSRMGI 9
           +NQS MG+
Sbjct: 572 MNQSMMGM 579
>NP_001182484
          Length = 643

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   LNQSRMGI 9
           +NQS MG+
Sbjct: 590 MNQSMMGM 597
>XP_005247161
          Length = 382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLNQSRMGI 9
           G+N  R+GI
Sbjct: 160 GVNPERIGI 168
>XP_005247160
          Length = 399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GLNQSRMGI 9
           G+N  R+GI
Sbjct: 177 GVNPERIGI 185
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.138    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 377,393
Number of extensions: 357
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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