Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     299
NP_859049                                                              17    2528
NP_001269781                                                           17    2528
NP_659449                                                              17    2528
NP_001269782                                                           17    2528
NP_001269783                                                           17    2528
NP_001135772                                                           17    2528
XP_005252445                                                           17    2528
XP_006717455                                                           17    2528
XP_005246400                                                           17    2528
NP_689736                                                              17    2528
NP_000005                                                              17    4312
XP_006719119                                                           17    4312
NP_001032                                                              16    5631
NP_001099133                                                           16    5631
NP_001230589                                                           16    5631
NP_001230590                                                           16    5631
NP_690867                                                              16    5631
NP_001714                                                              16    7355
NP_004659                                                              16    7355
NP_057043                                                              16    7355
NP_001268885                                                           16    7355
NP_001075019                                                           16    7355
NP_001167531                                                           16    7355
NP_060254                                                              16    7355
NP_001137484                                                           16    7355
XP_006724836                                                           16    7355
XP_005262507                                                           16    7355
XP_006724835                                                           16    7355
XP_006724834                                                           16    7355
XP_006724833                                                           16    7355
XP_006724832                                                           16    7355
XP_006724831                                                           16    7355
XP_006724830                                                           16    7355
XP_005262504                                                           16    7355
XP_006716232                                                           16    7355
XP_006716231                                                           16    7355
XP_005249383                                                           16    7355
XP_005264901                                                           16    7355
XP_005264900                                                           16    7355
NP_001107578                                                           15    9605
NP_001245271                                                           15    9605
NP_001245269                                                           15    9605
NP_689582                                                              15    9605
NP_001245270                                                           15    9605
NP_001245272                                                           15    9605
NP_036467                                                              15    9605
NP_073613                                                              15    9605
NP_071918                                                              15    9605
NP_036229                                                              15    9605
XP_005272534                                                           15    9605
XP_005272533                                                           15    9605
XP_005272532                                                           15    9605
XP_005254649                                                           15    9605
XP_005254648                                                           15    9605
XP_005270500                                                           15    9605
XP_005270498                                                           15    9605
XP_005270497                                                           15    9605
NP_714922                                                              15    9605
>NP_004295
          Length = 1620

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GLLQFNLNE 9
           GLLQFNL+E
Sbjct: 164 GLLQFNLSE 172
>NP_859049
          Length = 287

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 205 LLQFNIN 211
>NP_001269781
          Length = 316

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 234 LLQFNIN 240
>NP_659449
          Length = 341

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 259 LLQFNIN 265
>NP_001269782
          Length = 287

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 205 LLQFNIN 211
>NP_001269783
          Length = 208

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 126 LLQFNIN 132
>NP_001135772
          Length = 308

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 228 LLQFNIN 234
>XP_005252445
          Length = 294

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 212 LLQFNIN 218
>XP_006717455
          Length = 317

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 235 LLQFNIN 241
>XP_005246400
          Length = 359

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 279 LLQFNIN 285
>NP_689736
          Length = 289

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LLQFNLN 8
           LLQFN+N
Sbjct: 209 LLQFNIN 215
>NP_000005
          Length = 1474

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLLQFNLN 8
           GL+QF++N
Sbjct: 403 GLVQFSIN 410
>XP_006719119
          Length = 1512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GLLQFNLN 8
           GL+QF++N
Sbjct: 403 GLVQFSIN 410
>NP_001032
          Length = 1827

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    LQFNLNE 9
            +QFNLN+
Sbjct: 1743 VQFNLNQ 1749
>NP_001099133
          Length = 238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQFNLNE 9
           +QFNLN+
Sbjct: 212 VQFNLND 218
>NP_001230589
          Length = 223

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQFNLNE 9
           +QFNLN+
Sbjct: 197 VQFNLND 203
>NP_001230590
          Length = 185

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LQFNLNE 9
           +QFNLN+
Sbjct: 159 VQFNLND 165
>NP_690867
          Length = 674

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLLQFNLN 8
           GLLQF+ N
Sbjct: 603 GLLQFDSN 610
>NP_001714
          Length = 2649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LQFNLNE 9
            L FN+NE
Sbjct: 2399 LHFNINE 2405
>NP_004659
          Length = 1857

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLLQFNL 7
           G+L+FNL
Sbjct: 642 GVLEFNL 648
>NP_057043
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QFNLNE 9
           +FNLNE
Sbjct: 254 EFNLNE 259
>NP_001268885
          Length = 3631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    QFNLNE 9
            QFNLN+
Sbjct: 2812 QFNLND 2817
>NP_001075019
          Length = 1593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>NP_001167531
          Length = 700

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLLQFNLNE 9
           G+LQ+ +NE
Sbjct: 103 GILQYFVNE 111
>NP_060254
          Length = 764

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLLQFNLNE 9
           G+LQ+ +NE
Sbjct: 103 GILQYFVNE 111
>NP_001137484
          Length = 258

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   QFNLNE 9
           +FNLNE
Sbjct: 216 EFNLNE 221
>XP_006724836
          Length = 1582

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_005262507
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724835
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724834
          Length = 1615

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724833
          Length = 1620

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724832
          Length = 1640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724831
          Length = 1640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006724830
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_005262504
          Length = 1642

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   LLQFNL 7
           LLQFNL
Sbjct: 273 LLQFNL 278
>XP_006716232
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLLQFNL 7
           G+L+FNL
Sbjct: 642 GVLEFNL 648
>XP_006716231
          Length = 2753

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GLLQFNL 7
           G+L+FNL
Sbjct: 642 GVLEFNL 648
>XP_005249383
          Length = 3186

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LQFNLNE 9
            L FN+NE
Sbjct: 2936 LHFNINE 2942
>XP_005264901
          Length = 705

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLLQFNLNE 9
           G+LQ+ +NE
Sbjct: 103 GILQYFVNE 111
>XP_005264900
          Length = 769

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GLLQFNLNE 9
           G+LQ+ +NE
Sbjct: 103 GILQYFVNE 111
>NP_001107578
          Length = 653

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 551 GLMAFNYN 558
>NP_001245271
          Length = 617

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 515 GLMAFNYN 522
>NP_001245269
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 550 GLMAFNYN 557
>NP_689582
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 503 GLMAFNYN 510
>NP_001245270
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 518 GLMAFNYN 525
>NP_001245272
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 483 GLMAFNYN 490
>NP_036467
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LQFNLNE 9
            L FN+NE
Sbjct: 1060 LSFNVNE 1066
>NP_073613
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GLLQFNLNE 9
          GLL++ +NE
Sbjct: 87 GLLEYFVNE 95
>NP_071918
          Length = 1883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GLLQFNLNE 9
           GLL FN  +
Sbjct: 310 GLLDFNFEQ 318
>NP_036229
          Length = 179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  LLQFNLNE 9
          L QF++NE
Sbjct: 33 LYQFSMNE 40
>XP_005272534
          Length = 1071

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LQFNLNE 9
            L FN+NE
Sbjct: 1033 LSFNVNE 1039
>XP_005272533
          Length = 1096

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LQFNLNE 9
            L FN+NE
Sbjct: 1058 LSFNVNE 1064
>XP_005272532
          Length = 1100

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LQFNLNE 9
            L FN+NE
Sbjct: 1062 LSFNVNE 1068
>XP_005254649
          Length = 1819

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GLLQFNLNE 9
           GLL FN  +
Sbjct: 333 GLLDFNFEQ 341
>XP_005254648
          Length = 1906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GLLQFNLNE 9
           GLL FN  +
Sbjct: 333 GLLDFNFEQ 341
>XP_005270500
          Length = 573

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 471 GLMAFNYN 478
>XP_005270498
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 503 GLMAFNYN 510
>XP_005270497
          Length = 621

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GLLQFNLN 8
           GL+ FN N
Sbjct: 519 GLMAFNYN 526
>NP_714922
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GLLQFNLNE 9
          G+L+F LN+
Sbjct: 6  GILKFFLNQ 14
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.320    0.146    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 481,664
Number of extensions: 828
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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