Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006816                                                              16    5631
NP_940686                                                              16    5631
NP_940870                                                              16    7355
XP_006721885                                                           16    7355
XP_006715495                                                           16    7355
XP_006715494                                                           16    7355
XP_006715493                                                           16    7355
NP_055672                                                              15    9605
NP_001157790                                                           15    9605
NP_001157791                                                           15    9605
NP_001157789                                                           15    9605
NP_001448                                                              15    9605
NP_056264                                                              15    9605
NP_001092086                                                           15    9605
NP_005867                                                              15    9605
NP_775871                                                              15    9605
NP_001005340                                                           15    9605
XP_005249635                                                           15    9605
XP_005265039                                                           15    9605
XP_005265038                                                           15    9605
XP_005265035                                                           15    9605
XP_005265034                                                           15    9605
XP_006712257                                                           15    9605
XP_006712256                                                           15    9605
XP_005246298                                                           15    9605
XP_005246297                                                           15    9605
XP_005246299                                                           15    9605
XP_006712255                                                           15    9605
XP_005246296                                                           15    9605
XP_006712254                                                           15    9605
XP_005246295                                                           15    9605
XP_006712253                                                           15    9605
XP_006712252                                                           15    9605
XP_005246294                                                           15    9605
XP_006712251                                                           15    9605
XP_005246293                                                           15    9605
XP_005246292                                                           15    9605
XP_006712250                                                           15    9605
XP_006711756                                                           15    9605
XP_005245738                                                           15    9605
XP_006711755                                                           15    9605
XP_005245737                                                           15    9605
XP_005245134                                                           15    9605
NP_620077                                                              15    9605
>NP_006816
          Length = 602

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   GLATTVKS 8
           GLA+TV+S
Sbjct: 467 GLASTVRS 474
>NP_940686
          Length = 259

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GLATTVKSR 9
           GLA  VKSR
Sbjct: 121 GLAEEVKSR 129
>NP_940870
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GLA T+KS
Sbjct: 447 GLANTMKS 454
>XP_006721885
          Length = 125

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2 LATTVKSR 9
         + TTVKSR
Sbjct: 1 MRTTVKSR 8
>XP_006715495
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GLA T+KS
Sbjct: 447 GLANTMKS 454
>XP_006715494
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GLA T+KS
Sbjct: 221 GLANTMKS 228
>XP_006715493
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GLA T+KS
Sbjct: 447 GLANTMKS 454
>NP_055672
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GL+T VKS
Sbjct: 530 GLSTLVKS 537
>NP_001157790
          Length = 2591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1623 GIASTVKT 1630
>NP_001157791
          Length = 2578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1623 GIASTVKT 1630
>NP_001157789
          Length = 2633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1654 GIASTVKT 1661
>NP_001448
          Length = 2602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1623 GIASTVKT 1630
>NP_056264
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATTVKSR 9
           LAT VK+R
Sbjct: 152 LATAVKAR 159
>NP_001092086
          Length = 253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATTVKSR 9
           LAT VK+R
Sbjct: 186 LATAVKAR 193
>NP_005867
          Length = 3267

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1360 LSTTVKS 1366
>NP_775871
          Length = 8384

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GLATTVKS 8
            GL+TT+ S
Sbjct: 3003 GLSTTISS 3010
>NP_001005340
          Length = 572

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           LATT+KS
Sbjct: 339 LATTLKS 345
>XP_005249635
          Length = 531

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           LATT+KS
Sbjct: 339 LATTLKS 345
>XP_005265039
          Length = 2177

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1654 GIASTVKT 1661
>XP_005265038
          Length = 2181

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1654 GIASTVKT 1661
>XP_005265035
          Length = 2609

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1654 GIASTVKT 1661
>XP_005265034
          Length = 2622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GLATTVKS 8
            G+A+TVK+
Sbjct: 1654 GIASTVKT 1661
>XP_006712257
          Length = 1718

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1360 LSTTVKS 1366
>XP_006712256
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           L+TTVKS
Sbjct: 511 LSTTVKS 517
>XP_005246298
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           L+TTVKS
Sbjct: 511 LSTTVKS 517
>XP_005246297
          Length = 2418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           L+TTVKS
Sbjct: 511 LSTTVKS 517
>XP_005246299
          Length = 2480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           L+TTVKS
Sbjct: 573 LSTTVKS 579
>XP_006712255
          Length = 2622

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1360 LSTTVKS 1366
>XP_005246296
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           L+TTVKS
Sbjct: 568 LSTTVKS 574
>XP_006712254
          Length = 2475

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   LATTVKS 8
           L+TTVKS
Sbjct: 568 LSTTVKS 574
>XP_005246295
          Length = 3114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1207 LSTTVKS 1213
>XP_006712253
          Length = 3117

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1210 LSTTVKS 1216
>XP_006712252
          Length = 3163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1256 LSTTVKS 1262
>XP_005246294
          Length = 3173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1266 LSTTVKS 1272
>XP_006712251
          Length = 3176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1269 LSTTVKS 1275
>XP_005246293
          Length = 3206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1299 LSTTVKS 1305
>XP_005246292
          Length = 3208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1301 LSTTVKS 1307
>XP_006712250
          Length = 3248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    LATTVKS 8
            L+TTVKS
Sbjct: 1341 LSTTVKS 1347
>XP_006711756
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GL+T VKS
Sbjct: 530 GLSTLVKS 537
>XP_005245738
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GL+T VKS
Sbjct: 493 GLSTLVKS 500
>XP_006711755
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GL+T VKS
Sbjct: 530 GLSTLVKS 537
>XP_005245737
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GLATTVKS 8
           GL+T VKS
Sbjct: 530 GLSTLVKS 537
>XP_005245134
          Length = 235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATTVKSR 9
           LAT VK+R
Sbjct: 168 LATAVKAR 175
>NP_620077
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   LATTVKSR 9
           LAT VK+R
Sbjct: 134 LATAVKAR 141
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.119    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 275,581
Number of extensions: 243
Number of successful extensions: 44
Number of sequences better than 10000.0: 44
Number of HSP's gapped: 44
Number of HSP's successfully gapped: 44
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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