Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     390
NP_001075109                                                           20     390
NP_000896                                                              20     390
NP_001273752                                                           18    1935
NP_001136105                                                           18    1935
NP_055123                                                              18    1935
NP_001238784                                                           18    1935
NP_001238780                                                           18    1935
NP_001238781                                                           18    1935
NP_001238782                                                           18    1935
XP_005256637                                                           18    1935
XP_005256636                                                           18    1935
NP_061156                                                              17    4312
NP_955394                                                              16    5631
NP_001230823                                                           16    5631
NP_001230820                                                           16    5631
NP_000370                                                              16    5631
NP_001230824                                                           16    5631
NP_955393                                                              16    5631
NP_001230821                                                           16    5631
NP_003279                                                              16    5631
NP_955395                                                              16    5631
NP_955392                                                              16    5631
NP_955391                                                              16    5631
NP_001094859                                                           16    5631
NP_000929                                                              16    5631
NP_998764                                                              16    7355
NP_060552                                                              16    7355
NP_001136121                                                           16    7355
NP_001154180                                                           16    7355
NP_004259                                                              16    7355
XP_006719561                                                           16    7355
XP_005252880                                                           16    7355
XP_005252879                                                           16    7355
XP_005252878                                                           16    7355
XP_005252877                                                           16    7355
XP_005266876                                                           16    7355
XP_006715392                                                           16    7355
XP_005266875                                                           16    7355
XP_006714901                                                           16    7355
XP_005248447                                                           16    7355
XP_005248446                                                           16    7355
NP_061063                                                              16    7355
NP_001092878                                                           16    7355
NP_061978                                                              15    9605
NP_000833                                                              15    9605
NP_001137303                                                           15    9605
NP_149107                                                              15    9605
NP_078948                                                              15    9605
NP_002527                                                              15    9605
NP_065868                                                              15    9605
NP_940967                                                              15    9605
XP_005268266                                                           15    9605
XP_006720366                                                           15    9605
XP_005268265                                                           15    9605
XP_006718893                                                           15    9605
XP_006718892                                                           15    9605
XP_006718891                                                           15    9605
XP_005263278                                                           15    9605
XP_005263277                                                           15    9605
XP_006713778                                                           15    9605
XP_005273123                                                           15    9605
XP_005273122                                                           15    9605
NP_059974                                                              15    9605
>NP_008835
          Length = 4128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GKKRLGLSG 9
            GKKRLGL G
Sbjct: 2701 GKKRLGLPG 2709
>NP_001075109
          Length = 4097

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GKKRLGLSG 9
            GKKRLGL G
Sbjct: 2701 GKKRLGLPG 2709
>NP_000896
          Length = 97

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1  GKKRLGLSG 9
          G KRLGLSG
Sbjct: 3  GNKRLGLSG 11
>NP_001273752
          Length = 246

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GKKRLGLSG 9
           G++RLGL+G
Sbjct: 231 GEERLGLAG 239
>NP_001136105
          Length = 880

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 712 GSKRLGIDG 720
>NP_055123
          Length = 880

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 712 GSKRLGIDG 720
>NP_001238784
          Length = 494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 326 GSKRLGIDG 334
>NP_001238780
          Length = 494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 326 GSKRLGIDG 334
>NP_001238781
          Length = 494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 326 GSKRLGIDG 334
>NP_001238782
          Length = 494

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 326 GSKRLGIDG 334
>XP_005256637
          Length = 879

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 711 GSKRLGIDG 719
>XP_005256636
          Length = 880

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRLG+ G
Sbjct: 712 GSKRLGIDG 720
>NP_061156
          Length = 434

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KRLGLSG 9
           KR+GLSG
Sbjct: 382 KRVGLSG 388
>NP_955394
          Length = 220

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_001230823
          Length = 152

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_001230820
          Length = 181

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 53 KRRLGLS 59
>NP_000370
          Length = 1333

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  KKRLGLSG 9
          +++LGLSG
Sbjct: 31 RRKLGLSG 38
>NP_001230824
          Length = 222

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_955393
          Length = 209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_001230821
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 55 KRRLGLS 61
>NP_003279
          Length = 206

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_955395
          Length = 200

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_955392
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_955391
          Length = 186

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          K+RLGLS
Sbjct: 78 KRRLGLS 84
>NP_001094859
          Length = 229

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   KKRLGLSG 9
           K+RLGL G
Sbjct: 115 KRRLGLLG 122
>NP_000929
          Length = 1174

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRL L+G
Sbjct: 389 GNKRLDLAG 397
>NP_998764
          Length = 913

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GKKRLGL 7
           GKKR G+
Sbjct: 231 GKKRFGI 237
>NP_060552
          Length = 1133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRL L+G
Sbjct: 358 GNKRLELAG 366
>NP_001136121
          Length = 912

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GKKRLGL 7
           GKKR G+
Sbjct: 230 GKKRFGI 236
>NP_001154180
          Length = 1075

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRL L+G
Sbjct: 300 GNKRLELAG 308
>NP_004259
          Length = 651

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KR+ LSG
Sbjct: 401 GHKRMRLSG 409
>XP_006719561
          Length = 875

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G KRL L+G
Sbjct: 358 GNKRLELAG 366
>XP_005252880
          Length = 886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GKKRLGL 7
           GKKR G+
Sbjct: 204 GKKRFGI 210
>XP_005252879
          Length = 887

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GKKRLGL 7
           GKKR G+
Sbjct: 205 GKKRFGI 211
>XP_005252878
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GKKRLGL 7
           GKKR G+
Sbjct: 390 GKKRFGI 396
>XP_005252877
          Length = 1073

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GKKRLGL 7
           GKKR G+
Sbjct: 391 GKKRFGI 397
>XP_005266876
          Length = 321

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKRLGL 7
           KKRLGL
Sbjct: 196 KKRLGL 201
>XP_006715392
          Length = 325

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKRLGL 7
           KKRLGL
Sbjct: 196 KKRLGL 201
>XP_005266875
          Length = 454

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKRLGL 7
           KKRLGL
Sbjct: 196 KKRLGL 201
>XP_006714901
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KKRLGLS 8
           K+RLGLS
Sbjct: 209 KERLGLS 215
>XP_005248447
          Length = 356

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           GK RL +SG
Sbjct: 340 GKSRLPVSG 348
>XP_005248446
          Length = 386

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           GK RL +SG
Sbjct: 370 GKSRLPVSG 378
>NP_061063
          Length = 515

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   KKRLGL 7
           KKRLGL
Sbjct: 196 KKRLGL 201
>NP_001092878
          Length = 242

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   KKRLGLS 8
           K+RLGLS
Sbjct: 209 KERLGLS 215
>NP_061978
          Length = 4242

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    GKKRLG 6
            G+KRLG
Sbjct: 3426 GRKRLG 3431
>NP_000833
          Length = 1180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KRLGLSG 9
           +RLGL+G
Sbjct: 291 RRLGLAG 297
>NP_001137303
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KRLGLSG 9
           +RLGL+G
Sbjct: 291 RRLGLAG 297
>NP_149107
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KKRLGLS 8
           KKRLG++
Sbjct: 635 KKRLGIN 641
>NP_078948
          Length = 903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           GK++LG  G
Sbjct: 568 GKQKLGFLG 576
>NP_002527
          Length = 688

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  GKKRLGLS 8
          GKK  G+S
Sbjct: 78 GKKNFGIS 85
>NP_065868
          Length = 936

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          KKR+GL+
Sbjct: 12 KKRMGLN 18
>NP_940967
          Length = 692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           G +RL LSG
Sbjct: 133 GLRRLDLSG 141
>XP_005268266
          Length = 873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KKRLGLS 8
           KKRLG++
Sbjct: 529 KKRLGIN 535
>XP_006720366
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KKRLGLS 8
           KKRLG++
Sbjct: 647 KKRLGIN 653
>XP_005268265
          Length = 991

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   KKRLGLS 8
           KKRLG++
Sbjct: 647 KKRLGIN 653
>XP_006718893
          Length = 1180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KRLGLSG 9
           +RLGL+G
Sbjct: 291 RRLGLAG 297
>XP_006718892
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KRLGLSG 9
           +RLGL+G
Sbjct: 291 RRLGLAG 297
>XP_006718891
          Length = 1212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KRLGLSG 9
           +RLGL+G
Sbjct: 291 RRLGLAG 297
>XP_005263278
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           GK++LG  G
Sbjct: 285 GKQKLGFLG 293
>XP_005263277
          Length = 759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GKKRLGLSG 9
           GK++LG  G
Sbjct: 424 GKQKLGFLG 432
>XP_006713778
          Length = 923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  KKRLGLS 8
          KKR+GL+
Sbjct: 12 KKRMGLN 18
>XP_005273123
          Length = 432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  GKKRLG 6
          G+KRLG
Sbjct: 28 GRKRLG 33
>XP_005273122
          Length = 464

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  GKKRLG 6
          G+KRLG
Sbjct: 28 GRKRLG 33
>NP_059974
          Length = 311

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GKKRLGLSG 9
          GKK + L+G
Sbjct: 88 GKKSISLAG 96
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.144    0.403 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 645,579
Number of extensions: 1205
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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