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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003985                                                              17    3301
NP_000890                                                              17    3301
NP_619639                                                              16    7355
NP_733842                                                              16    7355
NP_006297                                                              16    7355
NP_789790                                                              16    7355
NP_056968                                                              16    7355
XP_005258905                                                           16    7355
NP_001268392                                                           16    7355
NP_062539                                                              15    9605
NP_009069                                                              15    9605
NP_002189                                                              15    9605
NP_001159773                                                           15    9605
NP_078888                                                              15    9605
XP_005260818                                                           15    9605
XP_005260817                                                           15    9605
XP_006723659                                                           15    9605
XP_005260815                                                           15    9605
XP_006723658                                                           15    9605
XP_006722146                                                           15    9605
XP_005256659                                                           15    9605
XP_005256658                                                           15    9605
XP_006721565                                                           15    9605
XP_006721564                                                           15    9605
XP_006721563                                                           15    9605
XP_005256655                                                           15    9605
XP_005256654                                                           15    9605
XP_006721562                                                           15    9605
XP_003846647                                                           15    9605

>NP_003985
          Length = 245

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SSTL
Sbjct: 163 CVVSSTL 169



>NP_000890
          Length = 273

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SSTL
Sbjct: 163 CVVSSTL 169



>NP_619639
          Length = 4074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GKCIISSTL 9
            G  IISSTL
Sbjct: 3012 GSWIISSTL 3020



>NP_733842
          Length = 3396

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    GKCIISSTL 9
            G  IISSTL
Sbjct: 3012 GSWIISSTL 3020



>NP_006297
          Length = 1233

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    GKCIISSTL 9
            G C+IS  L
Sbjct: 1208 GDCVISKVL 1216



>NP_789790
          Length = 991

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GKCIISS 7
           GKC ISS
Sbjct: 722 GKCDISS 728



>NP_056968
          Length = 519

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKCIISSTL 9
           G CI +STL
Sbjct: 307 GYCISASTL 315



>XP_005258905
          Length = 903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GKCIISS 7
           GKC ISS
Sbjct: 631 GKCDISS 637



>NP_001268392
          Length = 1211

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    GKCIISSTL 9
            G C+IS  L
Sbjct: 1186 GDCVISKVL 1194



>NP_062539
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SST+
Sbjct: 256 CLLSSTI 262



>NP_009069
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GKCIISSTL 9
           GK  ISS+L
Sbjct: 375 GKAFISSSL 383



>NP_002189
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   CIISSTL 9
           C +SSTL
Sbjct: 186 CAVSSTL 192



>NP_001159773
          Length = 702

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KCIISSTL 9
           KC+IS+ +
Sbjct: 263 KCVISTNI 270



>NP_078888
          Length = 779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KCIISSTL 9
           KC+IS+ +
Sbjct: 340 KCVISTNI 347



>XP_005260818
          Length = 491

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3  CIISSTL 9
          C++SST+
Sbjct: 75 CLLSSTI 81



>XP_005260817
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SST+
Sbjct: 176 CLLSSTI 182



>XP_006723659
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SST+
Sbjct: 256 CLLSSTI 262



>XP_005260815
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SST+
Sbjct: 256 CLLSSTI 262



>XP_006723658
          Length = 672

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   CIISSTL 9
           C++SST+
Sbjct: 256 CLLSSTI 262



>XP_006722146
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   KCIISSTL 9
           KC+IS+ +
Sbjct: 340 KCVISTNI 347



>XP_005256659
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 204 CLISST 209



>XP_005256658
          Length = 339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 204 CLISST 209



>XP_006721565
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 239 CLISST 244



>XP_006721564
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 239 CLISST 244



>XP_006721563
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 239 CLISST 244



>XP_005256655
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 239 CLISST 244



>XP_005256654
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 239 CLISST 244



>XP_006721562
          Length = 374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   CIISST 8
           C+ISST
Sbjct: 239 CLISST 244



>XP_003846647
          Length = 516

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  KCIISSTL 9
          KC+IS+ +
Sbjct: 77 KCVISTNI 84



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.322    0.135    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,081
Number of extensions: 513
Number of successful extensions: 29
Number of sequences better than 10000.0: 29
Number of HSP's gapped: 29
Number of HSP's successfully gapped: 29
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)