Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              19     869
XP_006716142                                                           19     869
XP_005250088                                                           19     869
XP_006716141                                                           19     869
XP_005250085                                                           19     869
XP_006716140                                                           19     869
XP_005250084                                                           19     869
XP_005250083                                                           19     869
XP_005250082                                                           19     869
NP_056261                                                              18    1935
XP_006711822                                                           18    1935
XP_006711821                                                           18    1935
NP_006454                                                              17    2528
NP_998787                                                              17    2528
NP_964010                                                              17    2528
NP_001129663                                                           17    2528
NP_056308                                                              17    2528
XP_005264148                                                           17    2528
XP_005264145                                                           17    2528
XP_006711984                                                           17    2528
XP_006711983                                                           17    2528
NP_065850                                                              17    3301
XP_006717993                                                           17    3301
XP_006717992                                                           17    3301
XP_006717991                                                           17    3301
NP_065883                                                              17    4312
NP_068767                                                              17    4312
NP_775960                                                              17    4312
NP_998814                                                              17    4312
NP_060718                                                              17    4312
XP_005269584                                                           17    4312
XP_005269583                                                           17    4312
XP_006717688                                                           17    4312
XP_005269582                                                           17    4312
XP_005251991                                                           17    4312
XP_005245423                                                           17    4312
XP_005245425                                                           17    4312
NP_001164269                                                           17    4312
NP_078836                                                              16    5631
XP_005269208                                                           16    5631
XP_005269207                                                           16    5631
NP_057132                                                              16    7355
NP_001243643                                                           15    9605
NP_002151                                                              15    9605
NP_821075                                                              15    9605
NP_443083                                                              15    9605
NP_821074                                                              15    9605
NP_001230405                                                           15    9605
NP_079375                                                              15    9605
NP_055699                                                              15    9605
NP_001017392                                                           15    9605
NP_001008781                                                           15    9605
XP_006721642                                                           15    9605
XP_006721641                                                           15    9605
XP_006719952                                                           15    9605
XP_006719951                                                           15    9605
XP_005266643                                                           15    9605
XP_006718827                                                           15    9605
XP_005252030                                                           15    9605
XP_006717163                                                           15    9605
XP_006717162                                                           15    9605
XP_006717161                                                           15    9605
XP_006717160                                                           15    9605
XP_005252029                                                           15    9605
XP_006717159                                                           15    9605
>NP_733751
          Length = 4911

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 915 GIGAVVLPG 923
>XP_006716142
          Length = 4927

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>XP_005250088
          Length = 4928

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>XP_006716141
          Length = 4959

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>XP_005250085
          Length = 4979

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>XP_006716140
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>XP_005250084
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>XP_005250083
          Length = 4982

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 915 GIGAVVLPG 923
>XP_005250082
          Length = 4983

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           GI AVVLPG
Sbjct: 916 GIGAVVLPG 924
>NP_056261
          Length = 2275

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IRAVVLPG 9
           ++AVVLPG
Sbjct: 126 VKAVVLPG 133
>XP_006711822
          Length = 2266

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IRAVVLPG 9
           ++AVVLPG
Sbjct: 117 VKAVVLPG 124
>XP_006711821
          Length = 2301

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IRAVVLPG 9
           ++AVVLPG
Sbjct: 152 VKAVVLPG 159
>NP_006454
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 253 GLRHVVVPG 261
>NP_998787
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 253 GLRHVVVPG 261
>NP_964010
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 253 GLRHVVVPG 261
>NP_001129663
          Length = 851

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+RA+ +PG
Sbjct: 363 GLRALAMPG 371
>NP_056308
          Length = 859

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+RA+ +PG
Sbjct: 363 GLRALAMPG 371
>XP_005264148
          Length = 289

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 118 GLRHVVVPG 126
>XP_005264145
          Length = 424

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 253 GLRHVVVPG 261
>XP_006711984
          Length = 457

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 300 GLRHVVVPG 308
>XP_006711983
          Length = 471

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R VV+PG
Sbjct: 300 GLRHVVVPG 308
>NP_065850
          Length = 436

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIRAVVLP 8
           G+R VVLP
Sbjct: 265 GLRCVVLP 272
>XP_006717993
          Length = 436

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIRAVVLP 8
           G+R VVLP
Sbjct: 265 GLRCVVLP 272
>XP_006717992
          Length = 436

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIRAVVLP 8
           G+R VVLP
Sbjct: 265 GLRCVVLP 272
>XP_006717991
          Length = 436

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIRAVVLP 8
           G+R VVLP
Sbjct: 265 GLRCVVLP 272
>NP_065883
          Length = 1237

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RAVVLPG 9
           +AVVLPG
Sbjct: 422 KAVVLPG 428
>NP_068767
          Length = 911

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GIRAVVLPG 9
           G+R + LPG
Sbjct: 667 GVRCLCLPG 675
>NP_775960
          Length = 1285

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GIRAVVLPG 9
           G  AVVLPG
Sbjct: 711 GSPAVVLPG 719
>NP_998814
          Length = 337

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GIRAVVLP 8
           GI++V+LP
Sbjct: 130 GIKSVILP 137
>NP_060718
          Length = 605

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  IRAVVLPG 9
          IRA VLPG
Sbjct: 14 IRARVLPG 21
>XP_005269584
          Length = 221

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GIRAVVLP 8
          GI++V+LP
Sbjct: 14 GIKSVILP 21
>XP_005269583
          Length = 221

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GIRAVVLP 8
          GI++V+LP
Sbjct: 14 GIKSVILP 21
>XP_006717688
          Length = 314

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GIRAVVLP 8
           GI++V+LP
Sbjct: 130 GIKSVILP 137
>XP_005269582
          Length = 328

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GIRAVVLP 8
           GI++V+LP
Sbjct: 121 GIKSVILP 128
>XP_005251991
          Length = 953

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   GIRAVVLPG 9
           G  AVVLPG
Sbjct: 379 GSPAVVLPG 387
>XP_005245423
          Length = 1246

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RAVVLPG 9
           +AVVLPG
Sbjct: 431 KAVVLPG 437
>XP_005245425
          Length = 1299

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   RAVVLPG 9
           +AVVLPG
Sbjct: 484 KAVVLPG 490
>NP_001164269
          Length = 579

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GIRAVVLP 8
           G+RA+V P
Sbjct: 168 GVRAIVCP 175
>NP_078836
          Length = 686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IRAVVLPG 9
          +RA+V+PG
Sbjct: 34 LRALVVPG 41
>XP_005269208
          Length = 455

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IRAVVLPG 9
          +RA+V+PG
Sbjct: 34 LRALVVPG 41
>XP_005269207
          Length = 685

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  IRAVVLPG 9
          +RA+V+PG
Sbjct: 34 LRALVVPG 41
>NP_057132
          Length = 298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GIRAVVLPG 9
           G+R+VVL G
Sbjct: 201 GVRSVVLFG 209
>NP_001243643
          Length = 608

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4  AVVLPG 9
          AV+LPG
Sbjct: 92 AVILPG 97
>NP_002151
          Length = 2201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>NP_821075
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GIRAVVL 7
            G+RAVV+
Sbjct: 1036 GVRAVVM 1042
>NP_443083
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GIRAVVL 7
           G+RAVV+
Sbjct: 926 GVRAVVM 932
>NP_821074
          Length = 1113

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GIRAVVL 7
            G+RAVV+
Sbjct: 1044 GVRAVVM 1050
>NP_001230405
          Length = 1078

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GIRAVVL 7
            G+RAVV+
Sbjct: 1009 GVRAVVM 1015
>NP_079375
          Length = 1217

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GIRAVVLPG 9
           G+R V+ PG
Sbjct: 390 GLRRVMRPG 398
>NP_055699
          Length = 1082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GIRAVVLPG 9
          G+R+ V PG
Sbjct: 79 GLRSDVFPG 87
>NP_001017392
          Length = 1082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GIRAVVLPG 9
          G+R+ V PG
Sbjct: 79 GLRSDVFPG 87
>NP_001008781
          Length = 4557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GIRAVVLP 8
            G+R VV+P
Sbjct: 4134 GLRPVVVP 4141
>XP_006721642
          Length = 979

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GIRAVVLPG 9
           G+R V+ PG
Sbjct: 390 GLRRVMRPG 398
>XP_006721641
          Length = 1140

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GIRAVVLPG 9
           G+R V+ PG
Sbjct: 390 GLRRVMRPG 398
>XP_006719952
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GIRAVVL 7
           G+RAVV+
Sbjct: 926 GVRAVVM 932
>XP_006719951
          Length = 995

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GIRAVVL 7
           G+RAVV+
Sbjct: 926 GVRAVVM 932
>XP_005266643
          Length = 1098

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GIRAVVL 7
            G+RAVV+
Sbjct: 1029 GVRAVVM 1035
>XP_006718827
          Length = 3479

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GIRAVVLP 8
            G+R VV+P
Sbjct: 3024 GLRPVVVP 3031
>XP_005252030
          Length = 1837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>XP_006717163
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>XP_006717162
          Length = 1928

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>XP_006717161
          Length = 2019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>XP_006717160
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>XP_005252029
          Length = 2110

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
>XP_006717159
          Length = 2293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    GIRAVVLPG 9
            G+R+  LPG
Sbjct: 1216 GLRSTDLPG 1224
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.328    0.156    0.467 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 521,681
Number of extensions: 869
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.9 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package