Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001276866                                                           20     509
NP_004439                                                              20     509
NP_001276865                                                           20     509
NP_001005862                                                           20     509
XP_005257197                                                           20     509
XP_006721828                                                           20     509
NP_001268678                                                           17    2528
NP_079440                                                              17    2528
NP_001268677                                                           17    2528
XP_005271543                                                           17    2528
XP_005271542                                                           17    2528
XP_005271541                                                           17    2528
XP_005271539                                                           17    2528
XP_005271538                                                           17    2528
NP_001036189                                                           17    4312
XP_005254376                                                           16    5631
XP_006720539                                                           16    5631
XP_006720538                                                           16    5631
XP_005254375                                                           16    5631
XP_005254374                                                           16    5631
XP_006710508                                                           16    5631
XP_006710507                                                           16    5631
NP_689910                                                              16    5631
NP_001008227                                                           16    5631
NP_001137432                                                           16    7355
NP_001137431                                                           16    7355
XP_005264347                                                           16    7355
XP_005264346                                                           16    7355
XP_005264345                                                           16    7355
XP_005264344                                                           16    7355
NP_000284                                                              15    9605
NP_001027005                                                           15    9605
NP_060021                                                              15    9605
NP_001127913                                                           15    9605
NP_001127912                                                           15    9605
NP_056017                                                              15    9605
NP_689854                                                              15    9605
NP_149987                                                              15    9605
NP_001269809                                                           15    9605
NP_071735                                                              15    9605
NP_036345                                                              15    9605
XP_005256041                                                           15    9605
XP_005256040                                                           15    9605
XP_005255263                                                           15    9605
XP_005255261                                                           15    9605
XP_006721088                                                           15    9605
XP_005255260                                                           15    9605
XP_005255259                                                           15    9605
XP_005255258                                                           15    9605
XP_006719336                                                           15    9605
XP_006719335                                                           15    9605
XP_006717867                                                           15    9605
XP_006713446                                                           15    9605
XP_005265443                                                           15    9605
XP_005265442                                                           15    9605
XP_005265441                                                           15    9605
XP_005265440                                                           15    9605
NP_001127914                                                           15    9605
>NP_001276866
          Length = 1055

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GILIKRQQQ 9
           GILIKR+QQ
Sbjct: 672 GILIKRRQQ 680
>NP_004439
          Length = 1255

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GILIKRQQQ 9
           GILIKR+QQ
Sbjct: 672 GILIKRRQQ 680
>NP_001276865
          Length = 1240

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GILIKRQQQ 9
           GILIKR+QQ
Sbjct: 657 GILIKRRQQ 665
>NP_001005862
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GILIKRQQQ 9
           GILIKR+QQ
Sbjct: 642 GILIKRRQQ 650
>XP_005257197
          Length = 1225

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GILIKRQQQ 9
           GILIKR+QQ
Sbjct: 642 GILIKRRQQ 650
>XP_006721828
          Length = 1336

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GILIKRQQQ 9
           GILIKR+QQ
Sbjct: 753 GILIKRRQQ 761
>NP_001268678
          Length = 1261

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIKRQQQ
Sbjct: 935 LIKRQQQ 941
>NP_079440
          Length = 1321

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LIKRQQQ 9
            LIKRQQQ
Sbjct: 995  LIKRQQQ 1001
>NP_001268677
          Length = 1102

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIKRQQQ
Sbjct: 776 LIKRQQQ 782
>XP_005271543
          Length = 722

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIKRQQQ
Sbjct: 396 LIKRQQQ 402
>XP_005271542
          Length = 770

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIKRQQQ
Sbjct: 444 LIKRQQQ 450
>XP_005271541
          Length = 1203

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIKRQQQ
Sbjct: 877 LIKRQQQ 883
>XP_005271539
          Length = 1263

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIKRQQQ
Sbjct: 937 LIKRQQQ 943
>XP_005271538
          Length = 1369

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3    LIKRQQQ 9
            LIKRQQQ
Sbjct: 1043 LIKRQQQ 1049
>NP_001036189
          Length = 538

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GILIKRQQQ 9
           GILI RQQ+
Sbjct: 378 GILICRQQR 386
>XP_005254376
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIK+QQQ
Sbjct: 284 LIKKQQQ 290
>XP_006720539
          Length = 383

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIK+QQQ
Sbjct: 284 LIKKQQQ 290
>XP_006720538
          Length = 411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIK+QQQ
Sbjct: 312 LIKKQQQ 318
>XP_005254375
          Length = 411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIK+QQQ
Sbjct: 312 LIKKQQQ 318
>XP_005254374
          Length = 458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIK+QQQ
Sbjct: 359 LIKKQQQ 365
>XP_006710508
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GILIK+Q
Sbjct: 663 GILIKKQ 669
>XP_006710507
          Length = 719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GILIK+Q
Sbjct: 705 GILIKKQ 711
>NP_689910
          Length = 719

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GILIK+Q
Sbjct: 705 GILIKKQ 711
>NP_001008227
          Length = 398

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           LIK+QQQ
Sbjct: 299 LIKKQQQ 305
>NP_001137432
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GIL++RQ +
Sbjct: 13 GILVQRQSK 21
>NP_001137431
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GILIKRQQQ 9
           GIL++RQ +
Sbjct: 92  GILVQRQSK 100
>XP_005264347
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GIL++RQ +
Sbjct: 13 GILVQRQSK 21
>XP_005264346
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GIL++RQ +
Sbjct: 13 GILVQRQSK 21
>XP_005264345
          Length = 115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GIL++RQ +
Sbjct: 13 GILVQRQSK 21
>XP_005264344
          Length = 194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GILIKRQQQ 9
           GIL++RQ +
Sbjct: 92  GILVQRQSK 100
>NP_000284
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GIL+KR+
Sbjct: 745 GILLKRE 751
>NP_001027005
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GIL+KR+
Sbjct: 738 GILLKRE 744
>NP_060021
          Length = 1009

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GILIKRQQQ 9
           GILIK+ ++
Sbjct: 542 GILIKKPEE 550
>NP_001127913
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GI++KR Q+
Sbjct: 39 GIVVKRFQE 47
>NP_001127912
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GI++KR Q+
Sbjct: 39 GIVVKRFQE 47
>NP_056017
          Length = 1618

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 424 GLLGSRQQQ 432
>NP_689854
          Length = 1835

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKRQQQ 9
            +KRQQQ
Sbjct: 1009 VKRQQQ 1014
>NP_149987
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GI++KR Q+
Sbjct: 39 GIVVKRFQE 47
>NP_001269809
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GI++KR Q+
Sbjct: 39 GIVVKRFQE 47
>NP_071735
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           L+KR+QQ
Sbjct: 259 LLKREQQ 265
>NP_036345
          Length = 493

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 108 GVLHLRQQQ 116
>XP_005256041
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GIL+KR+
Sbjct: 738 GILLKRE 744
>XP_005256040
          Length = 1093

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GILIKRQ 7
           GIL+KR+
Sbjct: 745 GILLKRE 751
>XP_005255263
          Length = 1248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 485 GLLGSRQQQ 493
>XP_005255261
          Length = 1280

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 485 GLLGSRQQQ 493
>XP_006721088
          Length = 1592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 398 GLLGSRQQQ 406
>XP_005255260
          Length = 1636

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 442 GLLGSRQQQ 450
>XP_005255259
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 467 GLLGSRQQQ 475
>XP_005255258
          Length = 1679

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILIKRQQQ 9
           G+L  RQQQ
Sbjct: 485 GLLGSRQQQ 493
>XP_006719336
          Length = 1779

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   IKRQQQ 9
           +KRQQQ
Sbjct: 953 VKRQQQ 958
>XP_006719335
          Length = 1793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKRQQQ 9
            +KRQQQ
Sbjct: 1009 VKRQQQ 1014
>XP_006717867
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GILIKRQQQ 9
           GILIK+ ++
Sbjct: 542 GILIKKPEE 550
>XP_006713446
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GI++KR Q+
Sbjct: 39 GIVVKRFQE 47
>XP_005265443
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           L+KR+QQ
Sbjct: 170 LLKREQQ 176
>XP_005265442
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           L+KR+QQ
Sbjct: 259 LLKREQQ 265
>XP_005265441
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           L+KR+QQ
Sbjct: 259 LLKREQQ 265
>XP_005265440
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LIKRQQQ 9
           L+KR+QQ
Sbjct: 259 LLKREQQ 265
>NP_001127914
          Length = 544

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GILIKRQQQ 9
          GI++KR Q+
Sbjct: 39 GIVVKRFQE 47
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.144    0.370 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,030
Number of extensions: 960
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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