Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              19     665
NP_671714                                                              19     665
XP_006715890                                                           19     665
XP_005250160                                                           19     665
XP_005250159                                                           19     665
XP_006723934                                                           17    2528
NP_001166951                                                           17    3301
NP_001166950                                                           17    3301
NP_056000                                                              17    3301
NP_001159743                                                           17    3301
NP_001273721                                                           17    3301
NP_001273723                                                           17    3301
NP_001273724                                                           17    3301
NP_001273722                                                           17    3301
NP_694568                                                              17    3301
NP_056127                                                              17    3301
NP_075463                                                              17    3301
XP_005262309                                                           17    3301
XP_005262308                                                           17    3301
XP_006724700                                                           17    3301
XP_005262307                                                           17    3301
XP_006724699                                                           17    3301
XP_005262306                                                           17    3301
XP_006719812                                                           17    3301
XP_006714407                                                           17    3301
XP_006714406                                                           17    3301
XP_006714405                                                           17    3301
XP_005263349                                                           17    3301
XP_005263348                                                           17    3301
XP_005263347                                                           17    3301
XP_005263346                                                           17    3301
XP_005263345                                                           17    3301
XP_005263344                                                           17    3301
XP_005263343                                                           17    3301
XP_005263342                                                           17    3301
XP_005263341                                                           17    3301
XP_005263340                                                           17    3301
XP_005263339                                                           17    3301
NP_078858                                                              16    5631
NP_001278232                                                           16    5631
NP_001278214                                                           16    5631
NP_775837                                                              16    5631
XP_006724283                                                           16    5631
XP_006724282                                                           16    5631
XP_005261537                                                           16    5631
NP_001077083                                                           16    7355
NP_055887                                                              16    7355
NP_001096080                                                           16    7355
NP_443135                                                              16    7355
XP_006725237                                                           16    7355
XP_006721083                                                           16    7355
XP_005272597                                                           16    7355
NP_057297                                                              15    9605
NP_001241657                                                           15    9605
NP_001241658                                                           15    9605
NP_001121598                                                           15    9605
NP_005376                                                              15    9605
NP_001158508                                                           15    9605
NP_002532                                                              15    9605
NP_001003941                                                           15    9605
XP_006723329                                                           15    9605
XP_005259110                                                           15    9605
XP_005259109                                                           15    9605
XP_005254846                                                           15    9605
XP_005249816                                                           15    9605
XP_005249818                                                           15    9605
XP_005265233                                                           15    9605
XP_005265231                                                           15    9605
XP_006713237                                                           15    9605
XP_006713236                                                           15    9605
XP_006713235                                                           15    9605
XP_006713234                                                           15    9605
XP_005265230                                                           15    9605
NP_060378                                                              15    9605
>NP_005742
          Length = 3907

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GILDRSS+S
Sbjct: 1755 GILDRSSKS 1763
>NP_671714
          Length = 3899

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GILDRSS+S
Sbjct: 1755 GILDRSSKS 1763
>XP_006715890
          Length = 3860

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GILDRSS+S
Sbjct: 1708 GILDRSSKS 1716
>XP_005250160
          Length = 3939

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GILDRSS+S
Sbjct: 1787 GILDRSSKS 1795
>XP_005250159
          Length = 3952

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GILDRSS+S
Sbjct: 1787 GILDRSSKS 1795
>XP_006723934
          Length = 419

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  GILDRSSES 9
          GI+DRS E+
Sbjct: 15 GIMDRSKEN 23
>NP_001166951
          Length = 414

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 210 ILDRSSE 216
>NP_001166950
          Length = 463

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 259 ILDRSSE 265
>NP_056000
          Length = 516

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 312 ILDRSSE 318
>NP_001159743
          Length = 1277

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    ILDRSSE 8
            ILDRSSE
Sbjct: 1074 ILDRSSE 1080
>NP_001273721
          Length = 1339

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2    ILDRSSE 8
            ILDRSSE
Sbjct: 1136 ILDRSSE 1142
>NP_001273723
          Length = 596

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 393 ILDRSSE 399
>NP_001273724
          Length = 574

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 371 ILDRSSE 377
>NP_001273722
          Length = 512

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 309 ILDRSSE 315
>NP_694568
          Length = 652

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 449 ILDRSSE 455
>NP_056127
          Length = 5005

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>NP_075463
          Length = 3013

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GILDRSSE 8
            G++DRSS+
Sbjct: 1989 GVIDRSSD 1996
>XP_005262309
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_005262308
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_006724700
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_005262307
          Length = 495

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 291 ILDRSSE 297
>XP_006724699
          Length = 521

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 317 ILDRSSE 323
>XP_005262306
          Length = 523

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   ILDRSSE 8
           ILDRSSE
Sbjct: 319 ILDRSSE 325
>XP_006719812
          Length = 3019

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    GILDRSSE 8
            G++DRSS+
Sbjct: 1986 GVIDRSSD 1993
>XP_006714407
          Length = 5004

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2720 GILEKSSET 2728
>XP_006714406
          Length = 3680

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_006714405
          Length = 4103

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 1798 GILEKSSET 1806
>XP_005263349
          Length = 4410

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2105 GILEKSSET 2113
>XP_005263348
          Length = 4443

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2138 GILEKSSET 2146
>XP_005263347
          Length = 4640

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_005263346
          Length = 4983

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2678 GILEKSSET 2686
>XP_005263345
          Length = 4991

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_005263344
          Length = 5005

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_005263343
          Length = 5009

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_005263342
          Length = 5025

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2720 GILEKSSET 2728
>XP_005263341
          Length = 5026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_005263340
          Length = 5026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>XP_005263339
          Length = 5026

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GILDRSSES 9
            GIL++SSE+
Sbjct: 2721 GILEKSSET 2729
>NP_078858
          Length = 4981

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    GILDRSSE 8
            GILDR  E
Sbjct: 3359 GILDREKE 3366
>NP_001278232
          Length = 4983

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    GILDRSSE 8
            GILDR  E
Sbjct: 3361 GILDREKE 3368
>NP_001278214
          Length = 4982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1    GILDRSSE 8
            GILDR  E
Sbjct: 3361 GILDREKE 3368
>NP_775837
          Length = 2151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILDRSSES 9
           GILDR+  S
Sbjct: 106 GILDRAKRS 114
>XP_006724283
          Length = 2151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILDRSSES 9
           GILDR+  S
Sbjct: 106 GILDRAKRS 114
>XP_006724282
          Length = 2151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILDRSSES 9
           GILDR+  S
Sbjct: 106 GILDRAKRS 114
>XP_005261537
          Length = 2151

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GILDRSSES 9
           GILDR+  S
Sbjct: 106 GILDRAKRS 114
>NP_001077083
          Length = 523

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GILDRSSES 9
           G+L+RSS S
Sbjct: 451 GLLERSSMS 459
>NP_055887
          Length = 1281

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    GILDRSSES 9
            GI++RSS S
Sbjct: 1066 GIINRSSAS 1074
>NP_001096080
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDRSSES 9
           +DRSSES
Sbjct: 671 VDRSSES 677
>NP_443135
          Length = 1024

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDRSSES 9
           +DRSSES
Sbjct: 671 VDRSSES 677
>XP_006725237
          Length = 878

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDRSSES 9
           +DRSSES
Sbjct: 525 VDRSSES 531
>XP_006721083
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GILDRSSES 9
           G+L+RSS S
Sbjct: 451 GLLERSSMS 459
>XP_005272597
          Length = 1025

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LDRSSES 9
           +DRSSES
Sbjct: 672 VDRSSES 678
>NP_057297
          Length = 581

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDRSSE 8
           LDRSSE
Sbjct: 368 LDRSSE 373
>NP_001241657
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDRSSES 9
           ILD+ SES
Sbjct: 137 ILDKMSES 144
>NP_001241658
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDRSSES 9
           ILD+ SES
Sbjct: 137 ILDKMSES 144
>NP_001121598
          Length = 144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   ILDRSSES 9
           ILD+ SES
Sbjct: 137 ILDKMSES 144
>NP_005376
          Length = 1462

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 683 DRSSES 688
>NP_001158508
          Length = 1019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDRSSES 9
           I+D+SSE+
Sbjct: 289 IIDKSSEN 296
>NP_002532
          Length = 1023

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDRSSES 9
           I+D+SSE+
Sbjct: 293 IIDKSSEN 300
>NP_001003941
          Length = 427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDRSSES 9
           I+D+SSE+
Sbjct: 293 IIDKSSEN 300
>XP_006723329
          Length = 304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GILDRSSE 8
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
>XP_005259110
          Length = 411

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GILDRSSE 8
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
>XP_005259109
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GILDRSSE 8
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
>XP_005254846
          Length = 351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   LDRSSE 8
           LDRSSE
Sbjct: 138 LDRSSE 143
>XP_005249816
          Length = 1038

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDRSSES 9
           I+D+SSE+
Sbjct: 308 IIDKSSEN 315
>XP_005249818
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   ILDRSSES 9
           I+D+SSE+
Sbjct: 304 IIDKSSEN 311
>XP_005265233
          Length = 1163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 383 DRSSES 388
>XP_005265231
          Length = 1210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 430 DRSSES 435
>XP_006713237
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 573 DRSSES 578
>XP_006713236
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 573 DRSSES 578
>XP_006713235
          Length = 1353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 573 DRSSES 578
>XP_006713234
          Length = 1436

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 683 DRSSES 688
>XP_005265230
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   DRSSES 9
           DRSSES
Sbjct: 683 DRSSES 688
>NP_060378
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GILDRSSE 8
           G+LDRS +
Sbjct: 213 GLLDRSQK 220
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.299    0.123    0.297 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 396,712
Number of extensions: 494
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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