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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1135
XP_006716142                                                           18    1135
XP_005250088                                                           18    1135
XP_006716141                                                           18    1135
XP_005250085                                                           18    1135
XP_006716140                                                           18    1135
XP_005250084                                                           18    1135
XP_005250083                                                           18    1135
XP_005250082                                                           18    1135
NP_001157570                                                           18    1935
NP_004376                                                              18    1935
NP_001129633                                                           16    5631
NP_775789                                                              16    5631
XP_006716494                                                           16    5631
XP_005251231                                                           16    5631
XP_006716493                                                           16    5631
XP_006716492                                                           16    5631
XP_006716491                                                           16    5631
XP_006716490                                                           16    5631
NP_001129632                                                           16    5631
NP_078809                                                              16    7355
NP_067628                                                              16    7355
NP_004764                                                              16    7355
XP_005256012                                                           16    7355
XP_006723286                                                           15    9605
XP_006723285                                                           15    9605
NP_002437                                                              15    9605

>NP_733751
          Length = 4911

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4186 GIAESAALR 4194



>XP_006716142
          Length = 4927

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4202 GIAESAALR 4210



>XP_005250088
          Length = 4928

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4203 GIAESAALR 4211



>XP_006716141
          Length = 4959

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4234 GIAESAALR 4242



>XP_005250085
          Length = 4979

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4258 GIAESAALR 4266



>XP_006716140
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4257 GIAESAALR 4265



>XP_005250084
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4257 GIAESAALR 4265



>XP_005250083
          Length = 4982

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4257 GIAESAALR 4265



>XP_005250082
          Length = 4983

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    GIAESATLR 9
            GIAESA LR
Sbjct: 4258 GIAESAALR 4266



>NP_001157570
          Length = 1642

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GIAESATLR 9
           GIAE +TLR
Sbjct: 890 GIAEKSTLR 898



>NP_004376
          Length = 3396

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   GIAESATLR 9
           GIAE +TLR
Sbjct: 890 GIAEKSTLR 898



>NP_001129633
          Length = 590

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 171 GATESATIR 179



>NP_775789
          Length = 681

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 171 GATESATIR 179



>XP_006716494
          Length = 598

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 171 GATESATIR 179



>XP_005251231
          Length = 618

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 108 GATESATIR 116



>XP_006716493
          Length = 628

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 171 GATESATIR 179



>XP_006716492
          Length = 654

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 171 GATESATIR 179



>XP_006716491
          Length = 661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 151 GATESATIR 159



>XP_006716490
          Length = 663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 153 GATESATIR 161



>NP_001129632
          Length = 632

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GIAESATLR 9
           G  ESAT+R
Sbjct: 171 GATESATIR 179



>NP_078809
          Length = 411

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IAESATLR 9
           IAE+ATL+
Sbjct: 274 IAEAATLK 281



>NP_067628
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IAESATLR 9
           IAE+ATL+
Sbjct: 252 IAEAATLK 259



>NP_004764
          Length = 155

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   IAESATLR 9
           + ESATLR
Sbjct: 95  LGESATLR 102



>XP_005256012
          Length = 395

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   IAESATLR 9
           IAE+ATL+
Sbjct: 252 IAEAATLK 259



>XP_006723286
          Length = 524

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIAESATL 8
           G+A SATL
Sbjct: 309 GLAPSATL 316



>XP_006723285
          Length = 620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIAESATL 8
           G+A SATL
Sbjct: 405 GLAPSATL 412



>NP_002437
          Length = 954

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GIAESATL 8
           G+A SATL
Sbjct: 739 GLAPSATL 746



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.124    0.302 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 210,610
Number of extensions: 265
Number of successful extensions: 27
Number of sequences better than 10000.0: 27
Number of HSP's gapped: 27
Number of HSP's successfully gapped: 27
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)