Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              20     509
NP_001075109                                                           20     509
NP_004934                                                              17    3301
NP_001265225                                                           17    4312
NP_001265224                                                           17    4312
NP_919278                                                              17    4312
XP_006712460                                                           17    4312
XP_006712459                                                           17    4312
NP_071756                                                              17    4312
NP_000544                                                              16    5631
NP_001728                                                              16    5631
NP_001121132                                                           16    7355
NP_055689                                                              16    7355
NP_001268885                                                           16    7355
NP_055486                                                              16    7355
NP_115686                                                              16    7355
XP_005252330                                                           16    7355
XP_005249622                                                           16    7355
XP_005249621                                                           16    7355
XP_005263605                                                           16    7355
XP_005263604                                                           16    7355
XP_005263602                                                           16    7355
XP_005263600                                                           16    7355
NP_002113                                                              15    9605
NP_000048                                                              15    9605
NP_001274177                                                           15    9605
NP_001274176                                                           15    9605
NP_001274175                                                           15    9605
NP_064440                                                              15    9605
NP_001020414                                                           15    9605
NP_001020413                                                           15    9605
NP_001560                                                              15    9605
NP_001193830                                                           15    9605
NP_006301                                                              15    9605
NP_001017923                                                           15    9605
NP_001073333                                                           15    9605
XP_006726822                                                           15    9605
XP_005276672                                                           15    9605
XP_006726804                                                           15    9605
XP_006726803                                                           15    9605
XP_006726802                                                           15    9605
XP_005275601                                                           15    9605
XP_005275599                                                           15    9605
XP_006726062                                                           15    9605
XP_005275390                                                           15    9605
XP_003846516                                                           15    9605
XP_005275165                                                           15    9605
XP_005275010                                                           15    9605
XP_006725547                                                           15    9605
XP_006725445                                                           15    9605
XP_006725444                                                           15    9605
XP_005276974                                                           15    9605
XP_005274725                                                           15    9605
XP_006723875                                                           15    9605
XP_006723874                                                           15    9605
XP_005260273                                                           15    9605
XP_006723871                                                           15    9605
XP_006723870                                                           15    9605
XP_006723869                                                           15    9605
XP_006722328                                                           15    9605
XP_006722321                                                           15    9605
XP_006722320                                                           15    9605
XP_006722319                                                           15    9605
XP_006722318                                                           15    9605
XP_006722250                                                           15    9605
XP_006720695                                                           15    9605
XP_005267373                                                           15    9605
XP_005249957                                                           15    9605
XP_006715142                                                           15    9605
XP_005276137                                                           15    9605
XP_003120317                                                           15    9605
NP_006015                                                              15    9605
NP_001005214                                                           15    9605
NP_009007                                                              15    9605
>NP_008835
          Length = 4128

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GFYKLLYIT 9
           GFYKLL IT
Sbjct: 665 GFYKLLSIT 673
>NP_001075109
          Length = 4097

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GFYKLLYIT 9
           GFYKLL IT
Sbjct: 665 GFYKLLSIT 673
>NP_004934
          Length = 674

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  GFYKLL 6
          GFYKLL
Sbjct: 31 GFYKLL 36
>NP_001265225
          Length = 730

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GF KLLY
Sbjct: 295 GFQKLLY 301
>NP_001265224
          Length = 784

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GF KLLY
Sbjct: 349 GFQKLLY 355
>NP_919278
          Length = 1925

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GF KLLY
Sbjct: 360 GFQKLLY 366
>XP_006712460
          Length = 784

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GF KLLY
Sbjct: 349 GFQKLLY 355
>XP_006712459
          Length = 1914

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GF KLLY
Sbjct: 349 GFQKLLY 355
>NP_071756
          Length = 291

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GFYKLLYI 8
          GF+ LLY+
Sbjct: 46 GFFGLLYV 53
>NP_000544
          Length = 1432

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   GFYKLLYIT 9
           G Y+++Y+T
Sbjct: 634 GKYRIVYVT 642
>NP_001728
          Length = 559

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   GFYKLLYI 8
           G Y+L+Y+
Sbjct: 354 GLYELIYV 361
>NP_001121132
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GFYKLLYI 8
           G Y LLY+
Sbjct: 639 GLYGLLYV 646
>NP_055689
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GFYKLLYI 8
           G Y LLY+
Sbjct: 639 GLYGLLYV 646
>NP_001268885
          Length = 3631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2    FYKLLY 7
            FYKLL+
Sbjct: 2720 FYKLLF 2725
>NP_055486
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   GFYKLLYI 8
           G+Y+ LY+
Sbjct: 206 GYYRSLYL 213
>NP_115686
          Length = 183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  FYKLLYI 8
          FY+ LYI
Sbjct: 80 FYRALYI 86
>XP_005252330
          Length = 163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  FYKLLYI 8
          FY+ LYI
Sbjct: 80 FYRALYI 86
>XP_005249622
          Length = 1021

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   GFYKLLYI 8
           G+Y+ LY+
Sbjct: 206 GYYRSLYL 213
>XP_005249621
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   GFYKLLYI 8
           G+Y+ LY+
Sbjct: 181 GYYRSLYL 188
>XP_005263605
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GFYKLLYI 8
           G Y LLY+
Sbjct: 639 GLYGLLYV 646
>XP_005263604
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GFYKLLYI 8
           G Y LLY+
Sbjct: 639 GLYGLLYV 646
>XP_005263602
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GFYKLLYI 8
           G Y LLY+
Sbjct: 639 GLYGLLYV 646
>XP_005263600
          Length = 757

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GFYKLLYI 8
           G Y LLY+
Sbjct: 639 GLYGLLYV 646
>NP_002113
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>NP_000048
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLLYIT 9
           KLLY+T
Sbjct: 761 KLLYVT 766
>NP_001274177
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLLYIT 9
           KLLY+T
Sbjct: 386 KLLYVT 391
>NP_001274176
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLLYIT 9
           KLLY+T
Sbjct: 761 KLLYVT 766
>NP_001274175
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLLYIT 9
           KLLY+T
Sbjct: 761 KLLYVT 766
>NP_064440
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>NP_001020414
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GFY L+Y
Sbjct: 282 GFYCLVY 288
>NP_001020413
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GFY L+Y
Sbjct: 282 GFYCLVY 288
>NP_001560
          Length = 712

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GFY L+Y
Sbjct: 282 GFYCLVY 288
>NP_001193830
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   FYKLLYIT 9
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>NP_006301
          Length = 919

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   GFYKLLYIT 9
           GFY+  Y T
Sbjct: 158 GFYRSKYTT 166
>NP_001017923
          Length = 310

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  GFYKLLYI 8
          GF  LLY+
Sbjct: 61 GFLMLLYV 68
>NP_001073333
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   FYKLLYIT 9
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>XP_006726822
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 78 GFYRSKYTT 86
>XP_005276672
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 64 GFYRSKYTT 72
>XP_006726804
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 3  GFYRSKYTT 11
>XP_006726803
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 3  GFYRSKYTT 11
>XP_006726802
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 64 GFYRSKYTT 72
>XP_005275601
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005275599
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_006726062
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_005275390
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_003846516
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005275165
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_005275010
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_006725547
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_006725445
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 64 GFYRSKYTT 72
>XP_006725444
          Length = 232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 3  GFYRSKYTT 11
>XP_005276974
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 64 GFYRSKYTT 72
>XP_005274725
          Length = 708

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GFYKLLY 7
           GFY L+Y
Sbjct: 308 GFYCLVY 314
>XP_006723875
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2  FYKLLY 7
          FYKLL+
Sbjct: 19 FYKLLH 24
>XP_006723874
          Length = 542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FYKLLY 7
           FYKLL+
Sbjct: 119 FYKLLH 124
>XP_005260273
          Length = 556

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FYKLLY 7
           FYKLL+
Sbjct: 135 FYKLLH 140
>XP_006723871
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FYKLLY 7
           FYKLL+
Sbjct: 134 FYKLLH 139
>XP_006723870
          Length = 557

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FYKLLY 7
           FYKLL+
Sbjct: 135 FYKLLH 140
>XP_006723869
          Length = 558

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   FYKLLY 7
           FYKLL+
Sbjct: 135 FYKLLH 140
>XP_006722328
          Length = 307

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 78 GFYRSKYTT 86
>XP_006722321
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 64 GFYRSKYTT 72
>XP_006722320
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 3  GFYRSKYTT 11
>XP_006722319
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 3  GFYRSKYTT 11
>XP_006722318
          Length = 385

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 64 GFYRSKYTT 72
>XP_006722250
          Length = 764

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1  GFYKLLYIT 9
          GFY+  Y T
Sbjct: 3  GFYRSKYTT 11
>XP_006720695
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   KLLYIT 9
           KLLY+T
Sbjct: 107 KLLYVT 112
>XP_005267373
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  GFYKLLYI 8
          GF  LLY+
Sbjct: 61 GFLMLLYV 68
>XP_005249957
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   FYKLLYIT 9
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>XP_006715142
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005276137
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_003120317
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   FYKLLYIT 9
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>NP_006015
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 2   FYKLLYIT 9
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>NP_001005214
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   GFYKLLYI 8
           G +KL+Y+
Sbjct: 99  GVFKLIYL 106
>NP_009007
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   YKLLYI 8
           YKL+YI
Sbjct: 357 YKLVYI 362
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.338    0.163    0.509 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 534,685
Number of extensions: 964
Number of successful extensions: 74
Number of sequences better than 10000.0: 74
Number of HSP's gapped: 74
Number of HSP's successfully gapped: 74
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.3 bits)
S2: 28 (15.4 bits)

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