Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_619732                                                              18    1135
NP_443193                                                              18    1135
NP_001180405                                                           18    1135
XP_006715059                                                           18    1135
NP_060791                                                              17    2528
NP_061119                                                              17    4312
NP_613258                                                              17    4312
NP_613075                                                              17    4312
NP_001035248                                                           17    4312
NP_001010986                                                           17    4312
NP_775965                                                              17    4312
NP_004884                                                              17    4312
XP_006724816                                                           17    4312
XP_006724815                                                           17    4312
XP_006724814                                                           17    4312
XP_005262462                                                           17    4312
XP_005272192                                                           17    4312
XP_005272191                                                           17    4312
XP_005272189                                                           17    4312
NP_005397                                                              16    5631
NP_001167522                                                           16    5631
NP_006021                                                              16    5631
NP_001278030                                                           16    5631
NP_001005505                                                           16    5631
NP_004451                                                              16    5631
NP_066363                                                              16    5631
XP_006723899                                                           16    5631
XP_005265638                                                           16    5631
NP_001005284                                                           16    5631
NP_000304                                                              16    7355
NP_005132                                                              16    7355
NP_001171670                                                           16    7355
NP_000129                                                              16    7355
NP_055383                                                              16    7355
XP_005247683                                                           16    7355
NP_000072                                                              15    9605
NP_689777                                                              15    9605
NP_060360                                                              15    9605
NP_056058                                                              15    9605
NP_001138890                                                           15    9605
NP_004685                                                              15    9605
NP_001167637                                                           15    9605
NP_000261                                                              15    9605
NP_699196                                                              15    9605
NP_055401                                                              15    9605
XP_006724234                                                           15    9605
XP_005261462                                                           15    9605
XP_006722232                                                           15    9605
XP_005257846                                                           15    9605
XP_006716574                                                           15    9605
XP_006716573                                                           15    9605
XP_005250858                                                           15    9605
XP_005250857                                                           15    9605
XP_005248199                                                           15    9605
XP_005248198                                                           15    9605
XP_005248197                                                           15    9605
XP_005248196                                                           15    9605
XP_005273087                                                           15    9605
XP_006711794                                                           15    9605
XP_005273086                                                           15    9605
XP_005273085                                                           15    9605
XP_005273084                                                           15    9605
>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GFTVLS+RI
Sbjct: 1477 GFTVLSDRI 1485
>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GFTVLS+RI
Sbjct: 1272 GFTVLSDRI 1280
>NP_619732
          Length = 865

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GFTVLSNRI 9
           GFTV++N+I
Sbjct: 212 GFTVIANKI 220
>NP_443193
          Length = 970

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GFTVLSNRI 9
           GFTV++N+I
Sbjct: 317 GFTVIANKI 325
>NP_001180405
          Length = 970

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GFTVLSNRI 9
           GFTV++N+I
Sbjct: 317 GFTVIANKI 325
>XP_006715059
          Length = 1042

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   GFTVLSNRI 9
           GFTV++N+I
Sbjct: 389 GFTVIANKI 397
>NP_060791
          Length = 353

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTVLSNRI 9
           FT+L NRI
Sbjct: 208 FTILDNRI 215
>NP_061119
          Length = 372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GFTVLSNR 8
           GFT+LS++
Sbjct: 182 GFTILSSK 189
>NP_613258
          Length = 372

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 182 GFTVLSTK 189
>NP_613075
          Length = 369

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 182 GFTVLSTK 189
>NP_001035248
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 181 GFTVLSTK 188
>NP_001010986
          Length = 1119

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT L NR
Sbjct: 512 GFTFLGNR 519
>NP_775965
          Length = 1132

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT L NR
Sbjct: 512 GFTFLGNR 519
>NP_004884
          Length = 371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 181 GFTVLSTK 188
>XP_006724816
          Length = 1105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_006724815
          Length = 1105

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_006724814
          Length = 1116

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_005262462
          Length = 1129

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT L NR
Sbjct: 509 GFTFLGNR 516
>XP_005272192
          Length = 198

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 181 GFTVLSTK 188
>XP_005272191
          Length = 199

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 182 GFTVLSTK 189
>XP_005272189
          Length = 368

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GFTVLS +
Sbjct: 181 GFTVLSTK 188
>NP_005397
          Length = 1354

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1   GFTVLSNR 8
           GFT  SNR
Sbjct: 396 GFTYYSNR 403
>NP_001167522
          Length = 1150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF VLSN+
Sbjct: 897 GFLVLSNQ 904
>NP_006021
          Length = 1143

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF VLSN+
Sbjct: 890 GFLVLSNQ 897
>NP_001278030
          Length = 1076

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF VLSN+
Sbjct: 821 GFLVLSNQ 828
>NP_001005505
          Length = 1145

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF VLSN+
Sbjct: 890 GFLVLSNQ 897
>NP_004451
          Length = 760

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  FTVLSNR 8
          +T+LSNR
Sbjct: 87 YTILSNR 93
>NP_066363
          Length = 1918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GFTVLSNRI 9
            GF  +SNRI
Sbjct: 1209 GFLQISNRI 1217
>XP_006723899
          Length = 1918

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    GFTVLSNRI 9
            GF  +SNRI
Sbjct: 1209 GFLQISNRI 1217
>XP_005265638
          Length = 1144

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF VLSN+
Sbjct: 891 GFLVLSNQ 898
>NP_001005284
          Length = 327

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GFTVLSN 7
           GFTVLS+
Sbjct: 219 GFTVLSS 225
>NP_000304
          Length = 676

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF +LSN+
Sbjct: 189 GFVMLSNK 196
>NP_005132
          Length = 491

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           G+TV+ NR
Sbjct: 278 GWTVIQNR 285
>NP_001171670
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           G+TV+ NR
Sbjct: 219 GWTVIQNR 226
>NP_000129
          Length = 2871

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   FTVLSNRI 9
           FTV+SN++
Sbjct: 187 FTVISNQM 194
>NP_055383
          Length = 940

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   FTVLSNRI 9
           FTV SNR+
Sbjct: 281 FTVNSNRL 288
>XP_005247683
          Length = 708

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GFTVLSNR 8
           GF +LSN+
Sbjct: 221 GFVMLSNK 228
>NP_000072
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GF++L+N++
Sbjct: 2375 GFSLLANQL 2383
>NP_689777
          Length = 3997

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>NP_060360
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>NP_056058
          Length = 863

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>NP_001138890
          Length = 2481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    GFTVLSN 7
            GF+++SN
Sbjct: 2058 GFSIISN 2064
>NP_004685
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TVLSNR 8
          TVLSNR
Sbjct: 82 TVLSNR 87
>NP_001167637
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TVLSNR 8
          TVLSNR
Sbjct: 82 TVLSNR 87
>NP_000261
          Length = 289

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 9/9 (100%)

Query: 1   GFTVLSNRI 9
           GF++++N++
Sbjct: 237 GFSLITNKV 245
>NP_699196
          Length = 567

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FTVLSNRI 9
           FT+  NRI
Sbjct: 559 FTICGNRI 566
>NP_055401
          Length = 714

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TVLSNR 8
           TVLSNR
Sbjct: 365 TVLSNR 370
>XP_006724234
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    GFTVLSN 7
            GF+++SN
Sbjct: 1940 GFSIISN 1946
>XP_005261462
          Length = 2473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 1    GFTVLSN 7
            GF+++SN
Sbjct: 2050 GFSIISN 2056
>XP_006722232
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TVLSNR 8
          TVLSNR
Sbjct: 82 TVLSNR 87
>XP_005257846
          Length = 523

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TVLSNR 8
          TVLSNR
Sbjct: 82 TVLSNR 87
>XP_006716574
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>XP_006716573
          Length = 1776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>XP_005250858
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>XP_005250857
          Length = 4022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTVLSNRI 9
           GFT L+N +
Sbjct: 490 GFTYLTNSL 498
>XP_005248199
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FTVLSNRI 9
           FT+  NRI
Sbjct: 418 FTICGNRI 425
>XP_005248198
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FTVLSNRI 9
           FT+  NRI
Sbjct: 418 FTICGNRI 425
>XP_005248197
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FTVLSNRI 9
           FT+  NRI
Sbjct: 433 FTICGNRI 440
>XP_005248196
          Length = 441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   FTVLSNRI 9
           FT+  NRI
Sbjct: 433 FTICGNRI 440
>XP_005273087
          Length = 2788

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GF++L+N++
Sbjct: 2375 GFSLLANQL 2383
>XP_006711794
          Length = 3022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GF++L+N++
Sbjct: 1596 GFSLLANQL 1604
>XP_005273086
          Length = 3264

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GF++L+N++
Sbjct: 2375 GFSLLANQL 2383
>XP_005273085
          Length = 3755

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GF++L+N++
Sbjct: 2329 GFSLLANQL 2337
>XP_005273084
          Length = 3801

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1    GFTVLSNRI 9
            GF++L+N++
Sbjct: 2375 GFSLLANQL 2383
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.145    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 403,148
Number of extensions: 650
Number of successful extensions: 64
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

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