Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_079521                                                              16    5631
XP_006722975                                                           16    5631
XP_006722974                                                           16    5631
XP_006722973                                                           16    5631
NP_037536                                                              16    7355
NP_005814                                                              16    7355
NP_001170826                                                           16    7355
NP_065890                                                              16    7355
XP_005255091                                                           16    7355
XP_006720900                                                           16    7355
XP_006720899                                                           16    7355
XP_005265403                                                           16    7355
NP_001727                                                              15    9605
NP_001001912                                                           15    9605
NP_066976                                                              15    9605
NP_006785                                                              15    9605
XP_005259247                                                           15    9605
XP_006722503                                                           15    9605
>NP_079521
          Length = 374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GFTFMTLRT 9
           G  F+TLRT
Sbjct: 320 GDAFLTLRT 328
>XP_006722975
          Length = 209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GFTFMTLRT 9
           G  F+TLRT
Sbjct: 155 GDAFLTLRT 163
>XP_006722974
          Length = 288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GFTFMTLRT 9
           G  F+TLRT
Sbjct: 234 GDAFLTLRT 242
>XP_006722973
          Length = 326

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GFTFMTLRT 9
           G  F+TLRT
Sbjct: 272 GDAFLTLRT 280
>NP_037536
          Length = 630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFMTLRT 9
           TFM LRT
Sbjct: 530 TFMKLRT 536
>NP_005814
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFMTLRT 9
           TFM LRT
Sbjct: 522 TFMKLRT 528
>NP_001170826
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFMTLRT 9
           TFM LRT
Sbjct: 522 TFMKLRT 528
>NP_065890
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GFTFMTLRT 9
           GF   TLRT
Sbjct: 107 GFCMSTLRT 115
>XP_005255091
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFMTLRT 9
           TFM LRT
Sbjct: 521 TFMKLRT 527
>XP_006720900
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFMTLRT 9
           TFM LRT
Sbjct: 522 TFMKLRT 528
>XP_006720899
          Length = 622

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   TFMTLRT 9
           TFM LRT
Sbjct: 522 TFMKLRT 528
>XP_005265403
          Length = 707

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   GFTFMTLRT 9
           GF   TLRT
Sbjct: 107 GFCMSTLRT 115
>NP_001727
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTFMTLRT 9
           +TF+ LRT
Sbjct: 222 YTFILLRT 229
>NP_001001912
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GFTFMTLR 8
           G TF+T+R
Sbjct: 158 GQTFLTIR 165
>NP_066976
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GFTFMTL 7
           GF F+TL
Sbjct: 610 GFIFLTL 616
>NP_006785
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GFTFMTLRT 9
           GF  M+L+T
Sbjct: 127 GFIIMSLKT 135
>XP_005259247
          Length = 231

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   FTFMTLRT 9
           +TF+ LRT
Sbjct: 103 YTFILLRT 110
>XP_006722503
          Length = 772

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   GFTFMTL 7
           GF F+TL
Sbjct: 610 GFIFLTL 616
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.147    0.454 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 415,656
Number of extensions: 526
Number of successful extensions: 18
Number of sequences better than 10000.0: 18
Number of HSP's gapped: 18
Number of HSP's successfully gapped: 18
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)

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