Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_958441                                                              20     299
NP_958439                                                              20     299
NP_005219                                                              20     299
NP_001184033                                                           18    1135
NP_005924                                                              18    1135
XP_006718903                                                           18    1135
XP_006718902                                                           18    1135
NP_065861                                                              17    2528
XP_005267973                                                           17    2528
NP_001243779                                                           17    4312
NP_596869                                                              17    4312
NP_079272                                                              17    4312
XP_006713858                                                           17    4312
XP_006712787                                                           17    4312
XP_006712786                                                           17    4312
NP_001254479                                                           17    4312
NP_057063                                                              16    5631
NP_004821                                                              16    5631
NP_001257451                                                           16    5631
NP_001257450                                                           16    5631
XP_006715675                                                           16    5631
XP_005267280                                                           16    5631
NP_057297                                                              16    7355
NP_067077                                                              16    7355
NP_001234926                                                           16    7355
NP_001039022                                                           16    7355
NP_006739                                                              16    7355
NP_001039021                                                           16    7355
NP_001269893                                                           16    7355
NP_006071                                                              16    7355
NP_002947                                                              16    7355
NP_001002010                                                           16    7355
NP_937883                                                              16    7355
XP_006720664                                                           16    7355
XP_005254592                                                           16    7355
XP_006719618                                                           16    7355
XP_006719617                                                           16    7355
XP_006719616                                                           16    7355
XP_006719615                                                           16    7355
XP_006719614                                                           16    7355
XP_005253652                                                           16    7355
XP_005253651                                                           16    7355
XP_005253650                                                           16    7355
XP_006715902                                                           16    7355
XP_006715901                                                           16    7355
XP_005250168                                                           16    7355
XP_005250167                                                           16    7355
NP_061072                                                              16    7355
NP_001123654                                                           16    7355
NP_997186                                                              15    9605
NP_005692                                                              15    9605
NP_001277239                                                           15    9605
NP_001277238                                                           15    9605
NP_001894                                                              15    9605
NP_001277241                                                           15    9605
NP_001277236                                                           15    9605
NP_008877                                                              15    9605
NP_001036053                                                           15    9605
NP_001036046                                                           15    9605
NP_003119                                                              15    9605
XP_005274250                                                           15    9605
XP_006718734                                                           15    9605
XP_006718733                                                           15    9605
XP_005274249                                                           15    9605
XP_006718732                                                           15    9605
XP_005271956                                                           15    9605
XP_006714599                                                           15    9605
XP_005264575                                                           15    9605
XP_006712150                                                           15    9605
XP_005264574                                                           15    9605
NP_114414                                                              15    9605
NP_842565                                                              15    9605
>NP_958441
          Length = 705

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GEKTKIISN 9
           G+KTKIISN
Sbjct: 485 GQKTKIISN 493
>NP_958439
          Length = 628

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GEKTKIISN 9
           G+KTKIISN
Sbjct: 485 GQKTKIISN 493
>NP_005219
          Length = 1210

 Score = 20.4 bits (41), Expect =   299
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   GEKTKIISN 9
           G+KTKIISN
Sbjct: 485 GQKTKIISN 493
>NP_001184033
          Length = 3972

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GEKTKIISN 9
            GEKTK++S+
Sbjct: 2308 GEKTKVLSS 2316
>NP_005924
          Length = 3969

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GEKTKIISN 9
            GEKTK++S+
Sbjct: 2305 GEKTKVLSS 2313
>XP_006718903
          Length = 2673

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GEKTKIISN 9
            GEKTK++S+
Sbjct: 1009 GEKTKVLSS 1017
>XP_006718902
          Length = 2964

 Score = 18.5 bits (36), Expect =  1135
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    GEKTKIISN 9
            GEKTK++S+
Sbjct: 1300 GEKTKVLSS 1308
>NP_065861
          Length = 509

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKTKIISN 9
           EKT+I+SN
Sbjct: 501 EKTQIVSN 508
>XP_005267973
          Length = 537

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   EKTKIISN 9
           EKT+I+SN
Sbjct: 529 EKTQIVSN 536
>NP_001243779
          Length = 34350

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EKTKIIS 8
            EKTKI+S
Sbjct: 6763 EKTKIVS 6769
>NP_596869
          Length = 33423

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EKTKIIS 8
            EKTKI+S
Sbjct: 5836 EKTKIVS 5842
>NP_079272
          Length = 751

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTKI+ N
Sbjct: 337 EKTKILMN 344
>XP_006713858
          Length = 712

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTKI+ N
Sbjct: 298 EKTKILMN 305
>XP_006712787
          Length = 33978

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EKTKIIS 8
            EKTKI+S
Sbjct: 6764 EKTKIVS 6770
>XP_006712786
          Length = 35484

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EKTKIIS 8
            EKTKI+S
Sbjct: 6764 EKTKIVS 6770
>NP_001254479
          Length = 35991

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    EKTKIIS 8
            EKTKI+S
Sbjct: 7080 EKTKIVS 7086
>NP_057063
          Length = 1365

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EKTKIIS 8
          EKTK+IS
Sbjct: 33 EKTKLIS 39
>NP_004821
          Length = 1368

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EKTKIIS 8
          EKTK+IS
Sbjct: 33 EKTKLIS 39
>NP_001257451
          Length = 1364

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EKTKIIS 8
          EKTK+IS
Sbjct: 33 EKTKLIS 39
>NP_001257450
          Length = 1359

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EKTKIIS 8
          EKTK+IS
Sbjct: 33 EKTKLIS 39
>XP_006715675
          Length = 747

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EKTKIIS 8
          EKTK+IS
Sbjct: 33 EKTKLIS 39
>XP_005267280
          Length = 1374

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  EKTKIIS 8
          EKTK+IS
Sbjct: 33 EKTKLIS 39
>NP_057297
          Length = 581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   GEKTKIISN 9
           G+K K+I+N
Sbjct: 175 GQKHKLINN 183
>NP_067077
          Length = 290

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   EKTKIIS 8
           EKTKII+
Sbjct: 212 EKTKIIA 218
>NP_001234926
          Length = 1438

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 754 EQTKVIDN 761
>NP_001039022
          Length = 293

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GEKTKIISN 9
          GEK ++IS+
Sbjct: 63 GEKLRVISD 71
>NP_006739
          Length = 316

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GEKTKIISN 9
          GEK ++IS+
Sbjct: 86 GEKLRVISD 94
>NP_001039021
          Length = 276

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GEKTKIISN 9
          GEK ++IS+
Sbjct: 46 GEKLRVISD 54
>NP_001269893
          Length = 249

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  GEKTKIISN 9
          GEK ++IS+
Sbjct: 63 GEKLRVISD 71
>NP_006071
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GEKTKIISN 9
           G KTK +SN
Sbjct: 685 GSKTKEMSN 693
>NP_002947
          Length = 1427

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 743 EQTKVIDN 750
>NP_001002010
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1  GEKTKII 7
          G KTKII
Sbjct: 43 GRKTKII 49
>NP_937883
          Length = 1392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 708 EQTKVIDN 715
>XP_006720664
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEKTKIIS 8
          GEK K+IS
Sbjct: 42 GEKFKLIS 49
>XP_005254592
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEKTKIIS 8
          GEK K+IS
Sbjct: 42 GEKFKLIS 49
>XP_006719618
          Length = 1394

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 708 EQTKVIDN 715
>XP_006719617
          Length = 1401

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 754 EQTKVIDN 761
>XP_006719616
          Length = 1405

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 719 EQTKVIDN 726
>XP_006719615
          Length = 1429

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 743 EQTKVIDN 750
>XP_006719614
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 754 EQTKVIDN 761
>XP_005253652
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 754 EQTKVIDN 761
>XP_005253651
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 754 EQTKVIDN 761
>XP_005253650
          Length = 1440

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E+TK+I N
Sbjct: 754 EQTKVIDN 761
>XP_006715902
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GEKTKIISN 9
           G KTK +SN
Sbjct: 685 GSKTKEMSN 693
>XP_006715901
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GEKTKIISN 9
           G KTK +SN
Sbjct: 685 GSKTKEMSN 693
>XP_005250168
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GEKTKIISN 9
           G KTK +SN
Sbjct: 685 GSKTKEMSN 693
>XP_005250167
          Length = 771

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GEKTKIISN 9
           G KTK +SN
Sbjct: 685 GSKTKEMSN 693
>NP_061072
          Length = 426

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEKTKIIS 8
          GEK K+IS
Sbjct: 71 GEKFKLIS 78
>NP_001123654
          Length = 397

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  GEKTKIIS 8
          GEK K+IS
Sbjct: 42 GEKFKLIS 49
>NP_997186
          Length = 1379

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    GEKTKIIS 8
            GE+T I+S
Sbjct: 1171 GEETSIVS 1178
>NP_005692
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GEKTKI 6
           GEKTK+
Sbjct: 219 GEKTKL 224
>NP_001277239
          Length = 783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 451 EATKLLSN 458
>NP_001277238
          Length = 803

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 471 EATKLLSN 478
>NP_001894
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 574 EATKLLSN 581
>NP_001277241
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 204 EATKLLSN 211
>NP_001277236
          Length = 841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 574 EATKLLSN 581
>NP_008877
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 976 EKTKVIES 983
>NP_001036053
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GEKTKI 6
           GEKTK+
Sbjct: 219 GEKTKL 224
>NP_001036046
          Length = 360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   GEKTKI 6
           GEKTK+
Sbjct: 219 GEKTKL 224
>NP_003119
          Length = 2364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 973 EKTKVIES 980
>XP_005274250
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 976 EKTKVIES 983
>XP_006718734
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 976 EKTKVIES 983
>XP_006718733
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 976 EKTKVIES 983
>XP_005274249
          Length = 2390

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 976 EKTKVIES 983
>XP_006718732
          Length = 2397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 983 EKTKVIES 990
>XP_005271956
          Length = 536

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 204 EATKLLSN 211
>XP_006714599
          Length = 906

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           E TK++SN
Sbjct: 574 EATKLLSN 581
>XP_005264575
          Length = 2351

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 960 EKTKVIES 967
>XP_006712150
          Length = 2364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 973 EKTKVIES 980
>XP_005264574
          Length = 2364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 973 EKTKVIES 980
>NP_114414
          Length = 585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  GEKTKIIS 8
          GEK  IIS
Sbjct: 56 GEKVNIIS 63
>NP_842565
          Length = 2155

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   EKTKIISN 9
           EKTK+I +
Sbjct: 960 EKTKVIES 967
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.297    0.123    0.301 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 453,104
Number of extensions: 746
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.0 bits)
S2: 28 (15.4 bits)

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