Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              20     509
NP_001239155                                                           17    4312
NP_006613                                                              17    4312
NP_001099001                                                           17    4312
NP_065870                                                              17    4312
NP_001156001                                                           17    4312
XP_005248807                                                           17    4312
XP_005248805                                                           17    4312
XP_005248804                                                           17    4312
XP_005248803                                                           17    4312
XP_005248802                                                           17    4312
XP_005248801                                                           17    4312
XP_005248800                                                           17    4312
NP_009118                                                              16    5631
NP_002953                                                              16    5631
XP_005266302                                                           16    5631
XP_005245487                                                           16    5631
XP_005245486                                                           16    5631
NP_001014443                                                           16    7355
NP_036607                                                              16    7355
NP_003244                                                              16    7355
NP_689417                                                              16    7355
XP_005261097                                                           16    7355
XP_005261096                                                           16    7355
XP_005261095                                                           16    7355
XP_005261094                                                           16    7355
XP_006720248                                                           16    7355
XP_005267848                                                           16    7355
XP_006711337                                                           16    7355
NP_060413                                                              16    7355
NP_001269973                                                           15    9605
NP_065076                                                              15    9605
NP_689976                                                              15    9605
NP_055062                                                              15    9605
NP_055805                                                              15    9605
NP_001269972                                                           15    9605
NP_919277                                                              15    9605
XP_006723662                                                           15    9605
XP_005260825                                                           15    9605
XP_006723661                                                           15    9605
XP_006720343                                                           15    9605
XP_006720167                                                           15    9605
XP_006720166                                                           15    9605
XP_005267550                                                           15    9605
XP_005267549                                                           15    9605
XP_005267548                                                           15    9605
XP_006720165                                                           15    9605
XP_006720164                                                           15    9605
XP_006720163                                                           15    9605
XP_006720162                                                           15    9605
XP_006720161                                                           15    9605
XP_006714485                                                           15    9605
XP_005263418                                                           15    9605
XP_005263417                                                           15    9605
XP_006714484                                                           15    9605
XP_005263416                                                           15    9605
XP_006714483                                                           15    9605
XP_005263415                                                           15    9605
>NP_115927
          Length = 1321

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GDMKKSSVT 9
           GDMKKS VT
Sbjct: 842 GDMKKSPVT 850
>NP_001239155
          Length = 671

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DMKKSSVT 9
           D+KK+S+T
Sbjct: 387 DLKKTSIT 394
>NP_006613
          Length = 685

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   DMKKSSVT 9
           D+KK+S+T
Sbjct: 401 DLKKTSIT 408
>NP_001099001
          Length = 1319

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 688 DTKKSSIT 695
>NP_065870
          Length = 1302

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 671 DTKKSSIT 678
>NP_001156001
          Length = 1515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 884 DTKKSSIT 891
>XP_005248807
          Length = 1182

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 551 DTKKSSIT 558
>XP_005248805
          Length = 1345

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 714 DTKKSSIT 721
>XP_005248804
          Length = 1378

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 747 DTKKSSIT 754
>XP_005248803
          Length = 1455

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 824 DTKKSSIT 831
>XP_005248802
          Length = 1515

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 884 DTKKSSIT 891
>XP_005248801
          Length = 1541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 910 DTKKSSIT 917
>XP_005248800
          Length = 1541

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSSVT 9
           D KKSS+T
Sbjct: 910 DTKKSSIT 917
>NP_009118
          Length = 376

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GDMKKSSV 8
           GD+KK++V
Sbjct: 158 GDLKKTAV 165
>NP_002953
          Length = 92

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GDMKKSSV 8
          G+MK+SS+
Sbjct: 45 GEMKESSI 52
>XP_005266302
          Length = 407

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GDMKKSSV 8
           GD+KK++V
Sbjct: 189 GDLKKTAV 196
>XP_005245487
          Length = 110

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GDMKKSSV 8
          G+MK+SS+
Sbjct: 63 GEMKESSI 70
>XP_005245486
          Length = 133

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GDMKKSSV 8
          G+MK+SS+
Sbjct: 86 GEMKESSI 93
>NP_001014443
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           G +KKSSV
Sbjct: 471 GSIKKSSV 478
>NP_036607
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           G +KKSSV
Sbjct: 471 GSIKKSSV 478
>NP_003244
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GDMKKSSVT 9
           G+M+ SSVT
Sbjct: 584 GEMQLSSVT 592
>NP_689417
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           GD+KK+ V
Sbjct: 155 GDLKKAKV 162
>XP_005261097
          Length = 1452

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GDMKKSSVT 9
           G+M+ SSVT
Sbjct: 584 GEMQLSSVT 592
>XP_005261096
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GDMKKSSVT 9
           G+M+ SSVT
Sbjct: 584 GEMQLSSVT 592
>XP_005261095
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GDMKKSSVT 9
           G+M+ SSVT
Sbjct: 584 GEMQLSSVT 592
>XP_005261094
          Length = 1591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   GDMKKSSVT 9
           G+M+ SSVT
Sbjct: 584 GEMQLSSVT 592
>XP_006720248
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           GD+KK+ V
Sbjct: 155 GDLKKAKV 162
>XP_005267848
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           GD+KK+ V
Sbjct: 155 GDLKKAKV 162
>XP_006711337
          Length = 381

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           G +KKSSV
Sbjct: 287 GSIKKSSV 294
>NP_060413
          Length = 711

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GDMKKSSV 8
           GD+KK+ V
Sbjct: 155 GDLKKAKV 162
>NP_001269973
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>NP_065076
          Length = 1873

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>NP_689976
          Length = 836

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GDMKKSSVT 9
           GD  KSS++
Sbjct: 102 GDASKSSIS 110
>NP_055062
          Length = 1499

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 492 GDIKKAS 498
>NP_055805
          Length = 2036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>NP_001269972
          Length = 2049

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>NP_919277
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006723662
          Length = 1920

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_005260825
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006723661
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720343
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD++KSS
Sbjct: 18 GDVRKSS 24
>XP_006720167
          Length = 1607

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720166
          Length = 2083

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_005267550
          Length = 2084

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_005267549
          Length = 2130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_005267548
          Length = 2131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720165
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720164
          Length = 2542

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720163
          Length = 2543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720162
          Length = 2589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006720161
          Length = 2590

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSS 7
          GD+KKS+
Sbjct: 8  GDVKKST 14
>XP_006714485
          Length = 1585

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 537 GDIKKAS 543
>XP_005263418
          Length = 1654

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 647 GDIKKAS 653
>XP_005263417
          Length = 1660

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 653 GDIKKAS 659
>XP_006714484
          Length = 1685

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 653 GDIKKAS 659
>XP_005263416
          Length = 1693

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 653 GDIKKAS 659
>XP_006714483
          Length = 1695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 647 GDIKKAS 653
>XP_005263415
          Length = 1701

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSS 7
           GD+KK+S
Sbjct: 653 GDIKKAS 659
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.295    0.111    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 413,961
Number of extensions: 433
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.1 bits)
S2: 28 (15.4 bits)

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