Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_115927                                                              19     869
NP_001129225                                                           17    3301
NP_001129224                                                           17    3301
NP_009196                                                              17    3301
NP_009117                                                              17    4312
NP_036218                                                              17    4312
NP_001193703                                                           17    4312
XP_005260322                                                           17    4312
XP_005260321                                                           17    4312
XP_005260320                                                           17    4312
XP_006723758                                                           17    4312
XP_006723757                                                           17    4312
XP_006723756                                                           17    4312
XP_006723755                                                           17    4312
XP_006723754                                                           17    4312
XP_006723753                                                           17    4312
XP_005260319                                                           17    4312
NP_004973                                                              16    5631
NP_000516                                                              16    5631
NP_001159762                                                           16    5631
NP_055497                                                              16    5631
XP_005253415                                                           16    5631
XP_006718289                                                           16    5631
XP_006716553                                                           16    5631
XP_006716552                                                           16    5631
XP_006716551                                                           16    5631
XP_006716550                                                           16    5631
NP_037514                                                              16    7355
NP_001035247                                                           16    7355
NP_001138786                                                           16    7355
XP_005263307                                                           16    7355
XP_006714391                                                           16    7355
XP_006714390                                                           16    7355
NP_001449                                                              15    9605
NP_001120959                                                           15    9605
NP_115495                                                              15    9605
NP_009118                                                              15    9605
NP_004534                                                              15    9605
NP_001258137                                                           15    9605
NP_001157980                                                           15    9605
NP_001157979                                                           15    9605
NP_003881                                                              15    9605
NP_036553                                                              15    9605
XP_005266302                                                           15    9605
XP_006715973                                                           15    9605
XP_005246675                                                           15    9605
XP_005246674                                                           15    9605
XP_005246673                                                           15    9605
XP_005246672                                                           15    9605
XP_005246670                                                           15    9605
XP_005246669                                                           15    9605
XP_005246668                                                           15    9605
XP_005246667                                                           15    9605
XP_005246665                                                           15    9605
XP_006712605                                                           15    9605
XP_006712604                                                           15    9605
XP_005246663                                                           15    9605
XP_005246660                                                           15    9605
XP_005246661                                                           15    9605
XP_005246659                                                           15    9605
XP_005246658                                                           15    9605
XP_005246657                                                           15    9605
XP_005246656                                                           15    9605
XP_005246655                                                           15    9605
XP_005246654                                                           15    9605
XP_005246653                                                           15    9605
XP_005246652                                                           15    9605
XP_005246649                                                           15    9605
XP_005246651                                                           15    9605
XP_005246650                                                           15    9605
XP_005246648                                                           15    9605
XP_005246647                                                           15    9605
>NP_115927
          Length = 1321

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GDMKKSLVT 9
           GDMKKS VT
Sbjct: 842 GDMKKSPVT 850
>NP_001129225
          Length = 601

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D KKSLVT
Sbjct: 278 DCKKSLVT 285
>NP_001129224
          Length = 677

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D KKSLVT
Sbjct: 321 DCKKSLVT 328
>NP_009196
          Length = 644

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D KKSLVT
Sbjct: 321 DCKKSLVT 328
>NP_009117
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>NP_036218
          Length = 886

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GDMKKSL 7
           GDM+KSL
Sbjct: 197 GDMEKSL 203
>NP_001193703
          Length = 413

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   GDMKKSL 7
           GDM+KSL
Sbjct: 197 GDMEKSL 203
>XP_005260322
          Length = 1810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D+KK LVT
Sbjct: 915 DLKKQLVT 922
>XP_005260321
          Length = 2365

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1470 DLKKQLVT 1477
>XP_005260320
          Length = 2370

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>XP_006723758
          Length = 2386

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1491 DLKKQLVT 1498
>XP_006723757
          Length = 2404

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>XP_006723756
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>XP_006723755
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>XP_006723754
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>XP_006723753
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>XP_005260319
          Length = 2442

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    DMKKSLVT 9
            D+KK LVT
Sbjct: 1547 DLKKQLVT 1554
>NP_004973
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GDMKKSLV 8
           GD++KS++
Sbjct: 213 GDLRKSMI 220
>NP_000516
          Length = 390

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GDMKKSLV 8
           GD++KS++
Sbjct: 203 GDLRKSMI 210
>NP_001159762
          Length = 303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GDMKKSLV 8
           GD++KS++
Sbjct: 116 GDLRKSMI 123
>NP_055497
          Length = 1047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D+KK L+T
Sbjct: 716 DLKKELIT 723
>XP_005253415
          Length = 424

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GDMKKSLV 8
           GD++KS++
Sbjct: 213 GDLRKSMI 220
>XP_006718289
          Length = 303

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   GDMKKSLV 8
           GD++KS++
Sbjct: 116 GDLRKSMI 123
>XP_006716553
          Length = 965

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D+KK L+T
Sbjct: 634 DLKKELIT 641
>XP_006716552
          Length = 1038

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D+KK L+T
Sbjct: 716 DLKKELIT 723
>XP_006716551
          Length = 1047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D+KK L+T
Sbjct: 716 DLKKELIT 723
>XP_006716550
          Length = 1047

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   DMKKSLVT 9
           D+KK L+T
Sbjct: 716 DLKKELIT 723
>NP_037514
          Length = 750

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GDMKKSLVT 9
           GD+  SLVT
Sbjct: 266 GDLSLSLVT 274
>NP_001035247
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSL 7
          GD+K+SL
Sbjct: 4  GDLKRSL 10
>NP_001138786
          Length = 399

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSL 7
          GD+K+SL
Sbjct: 4  GDLKRSL 10
>XP_005263307
          Length = 363

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSL 7
          GD+K+SL
Sbjct: 4  GDLKRSL 10
>XP_006714391
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSL 7
          GD+K+SL
Sbjct: 4  GDLKRSL 10
>XP_006714390
          Length = 390

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GDMKKSL 7
          GD+K+SL
Sbjct: 4  GDLKRSL 10
>NP_001449
          Length = 2725

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    GDMKKSLVT 9
            GD  K LVT
Sbjct: 1634 GDASKCLVT 1642
>NP_001120959
          Length = 2692

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    GDMKKSLVT 9
            GD  K LVT
Sbjct: 1634 GDASKCLVT 1642
>NP_115495
          Length = 6306

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    GDMKKSL 7
            G+M+KSL
Sbjct: 4327 GEMRKSL 4333
>NP_009118
          Length = 376

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GDMKKSLV 8
           GD+KK+ V
Sbjct: 158 GDLKKTAV 165
>NP_004534
          Length = 6669

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 5845 DMKESLI 5851
>NP_001258137
          Length = 8560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7581 DMKESLI 7587
>NP_001157980
          Length = 8525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>NP_001157979
          Length = 8525

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>NP_003881
          Length = 5405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    GDMKKSLVT 9
            GD+++ LVT
Sbjct: 4905 GDLQRLLVT 4913
>NP_036553
          Length = 1914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   GDMKKSL 7
           GD+KKS+
Sbjct: 832 GDIKKSV 838
>XP_005266302
          Length = 407

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GDMKKSLV 8
           GD+KK+ V
Sbjct: 189 GDLKKTAV 196
>XP_006715973
          Length = 2632

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1    GDMKKSLVT 9
            GD  K LVT
Sbjct: 1541 GDASKCLVT 1549
>XP_005246675
          Length = 5223

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 4244 DMKESLI 4250
>XP_005246674
          Length = 7553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 6574 DMKESLI 6580
>XP_005246673
          Length = 8018

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246672
          Length = 8277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246670
          Length = 8282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7303 DMKESLI 7309
>XP_005246669
          Length = 8282

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7303 DMKESLI 7309
>XP_005246668
          Length = 8308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246667
          Length = 8308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246665
          Length = 8339

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_006712605
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_006712604
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246663
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246660
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246661
          Length = 8370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246659
          Length = 8401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246658
          Length = 8401

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246657
          Length = 8432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246656
          Length = 8432

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246655
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246654
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246653
          Length = 8463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246652
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246649
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246651
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246650
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246648
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
>XP_005246647
          Length = 8494

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    DMKKSLV 8
            DMK+SL+
Sbjct: 7546 DMKESLI 7552
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.308    0.125    0.319 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 429,440
Number of extensions: 660
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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