Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_065681                                                              19     869
NP_066124                                                              19     869
XP_006717999                                                           19     869
NP_003239                                                              18    1935
NP_001258635                                                           17    2528
NP_112205                                                              17    2528
XP_005251390                                                           17    2528
XP_005251389                                                           17    2528
NP_003256                                                              17    4312
NP_653200                                                              17    4312
NP_001135747                                                           17    4312
NP_653181                                                              17    4312
NP_001243534                                                           17    4312
NP_001243533                                                           17    4312
NP_001243538                                                           17    4312
XP_006714357                                                           17    4312
XP_005244921                                                           17    4312
NP_004954                                                              16    5631
NP_001258523                                                           16    5631
NP_001186862                                                           16    5631
NP_055269                                                              16    5631
NP_653266                                                              16    5631
NP_001186863                                                           16    5631
NP_115605                                                              16    5631
NP_055672                                                              15    9605
NP_001273670                                                           15    9605
NP_116296                                                              15    9605
NP_001273668                                                           15    9605
NP_001273671                                                           15    9605
NP_001273669                                                           15    9605
NP_957717                                                              15    9605
NP_036329                                                              15    9605
NP_001122062                                                           15    9605
NP_000491                                                              15    9605
NP_001273283                                                           15    9605
NP_683766                                                              15    9605
NP_001273284                                                           15    9605
NP_002215                                                              15    9605
NP_001136099                                                           15    9605
NP_001128521                                                           15    9605
NP_001128520                                                           15    9605
NP_001128519                                                           15    9605
NP_001013682                                                           15    9605
NP_001136100                                                           15    9605
NP_060614                                                              15    9605
XP_006726140                                                           15    9605
XP_006726139                                                           15    9605
XP_006725960                                                           15    9605
XP_006725959                                                           15    9605
XP_006725536                                                           15    9605
XP_006725535                                                           15    9605
XP_006720096                                                           15    9605
XP_005267389                                                           15    9605
XP_006720095                                                           15    9605
XP_006720094                                                           15    9605
XP_006717095                                                           15    9605
XP_006717094                                                           15    9605
XP_005251923                                                           15    9605
XP_006715156                                                           15    9605
XP_006715155                                                           15    9605
XP_006715154                                                           15    9605
XP_006715065                                                           15    9605
XP_006715064                                                           15    9605
XP_006711756                                                           15    9605
XP_005245738                                                           15    9605
XP_006711755                                                           15    9605
XP_005245737                                                           15    9605
XP_005270918                                                           15    9605
NP_569736                                                              15    9605
>NP_065681
          Length = 1072

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAVVLLLHF 9
           GA VLLLHF
Sbjct: 385 GAGVLLLHF 393
>NP_066124
          Length = 1114

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAVVLLLHF 9
           GA VLLLHF
Sbjct: 385 GAGVLLLHF 393
>XP_006717999
          Length = 1207

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAVVLLLHF 9
           GA VLLLHF
Sbjct: 478 GAGVLLLHF 486
>NP_003239
          Length = 961

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  GAVVLLLH 8
          GA VLLLH
Sbjct: 6  GAAVLLLH 13
>NP_001258635
          Length = 233

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GAVVLLLHF 9
           G+ VLL HF
Sbjct: 183 GSAVLLFHF 191
>NP_112205
          Length = 453

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           GAVVLL H
Sbjct: 254 GAVVLLTH 261
>XP_005251390
          Length = 168

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GAVVLLLHF 9
           G+ VLL HF
Sbjct: 118 GSAVLLFHF 126
>XP_005251389
          Length = 239

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GAVVLLLHF 9
           G+ VLL HF
Sbjct: 189 GSAVLLFHF 197
>NP_003256
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VVLLLHF 9
           +VLL+HF
Sbjct: 719 IVLLIHF 725
>NP_653200
          Length = 329

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   GAVVLLLH 8
           G+VVL++H
Sbjct: 132 GSVVLIIH 139
>NP_001135747
          Length = 254

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  GAVVLLLH 8
          G+VVL++H
Sbjct: 57 GSVVLIIH 64
>NP_653181
          Length = 406

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G +VLLLH
Sbjct: 388 GGLVLLLH 395
>NP_001243534
          Length = 320

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G +VLLLH
Sbjct: 302 GGLVLLLH 309
>NP_001243533
          Length = 357

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G +VLLLH
Sbjct: 339 GGLVLLLH 346
>NP_001243538
          Length = 325

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G +VLLLH
Sbjct: 307 GGLVLLLH 314
>XP_006714357
          Length = 904

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   VVLLLHF 9
           +VLL+HF
Sbjct: 719 IVLLIHF 725
>XP_005244921
          Length = 229

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G +VLLLH
Sbjct: 211 GGLVLLLH 218
>NP_004954
          Length = 1073

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   GAVVLLL 7
           GAVVLLL
Sbjct: 441 GAVVLLL 447
>NP_001258523
          Length = 353

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  AVVLLLHF 9
          AVVLL H+
Sbjct: 54 AVVLLAHY 61
>NP_001186862
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVVLLLHF 9
           AVVLL H+
Sbjct: 202 AVVLLTHY 209
>NP_055269
          Length = 551

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVVLLLHF 9
           AVVLL H+
Sbjct: 261 AVVLLTHY 268
>NP_653266
          Length = 492

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVVLLLHF 9
           AVVLL H+
Sbjct: 193 AVVLLAHY 200
>NP_001186863
          Length = 426

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AVVLLLHF 9
           AVVLL H+
Sbjct: 136 AVVLLTHY 143
>NP_115605
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G VVL+LH
Sbjct: 627 GIVVLVLH 634
>NP_055672
          Length = 815

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 627 AAVLLLH 633
>NP_001273670
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AVVLLLH 8
           A+VL+LH
Sbjct: 228 AIVLVLH 234
>NP_116296
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AVVLLLH 8
           A+VL+LH
Sbjct: 188 AIVLVLH 194
>NP_001273668
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AVVLLLH 8
           A+VL+LH
Sbjct: 188 AIVLVLH 194
>NP_001273671
          Length = 420

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AVVLLLH 8
           A+VL+LH
Sbjct: 228 AIVLVLH 234
>NP_001273669
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AVVLLLH 8
           A+VL+LH
Sbjct: 188 AIVLVLH 194
>NP_957717
          Length = 380

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AVVLLLH 8
           A+VL+LH
Sbjct: 188 AIVLVLH 194
>NP_036329
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 655 AAVLLLH 661
>NP_001122062
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 274 AVVFLLH 280
>NP_000491
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 304 AVVFLLH 310
>NP_001273283
          Length = 751

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VVLLLHF 9
           V+LL HF
Sbjct: 460 VILLCHF 466
>NP_683766
          Length = 926

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VVLLLHF 9
           V+LL HF
Sbjct: 635 VILLCHF 641
>NP_001273284
          Length = 855

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   VVLLLHF 9
           V+LL HF
Sbjct: 564 VILLCHF 570
>NP_002215
          Length = 2671

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G+V+ LLH
Sbjct: 119 GSVIQLLH 126
>NP_001136099
          Length = 437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GAVVLLLH 8
           GAV+ L H
Sbjct: 211 GAVIALFH 218
>NP_001128521
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 55 GAMIAPLHF 63
>NP_001128520
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 44 GAMIAPLHF 52
>NP_001128519
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 44 GAMIAPLHF 52
>NP_001013682
          Length = 626

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  GAVVLLLH 8
          G  +LLLH
Sbjct: 9  GTCILLLH 16
>NP_001136100
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GAVVLLLH 8
           GAV+ L H
Sbjct: 189 GAVIALFH 196
>NP_060614
          Length = 476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   GAVVLLLH 8
           GAV+ L H
Sbjct: 211 GAVIALFH 218
>XP_006726140
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 106 AVVFLLH 112
>XP_006726139
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 263 AVVFLLH 269
>XP_006725960
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 106 AVVFLLH 112
>XP_006725959
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 263 AVVFLLH 269
>XP_006725536
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 106 AVVFLLH 112
>XP_006725535
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 263 AVVFLLH 269
>XP_006720096
          Length = 135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 87 GAMIAPLHF 95
>XP_005267389
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 44 GAMIAPLHF 52
>XP_006720095
          Length = 174

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 55 GAMIAPLHF 63
>XP_006720094
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 87 GAMIAPLHF 95
>XP_006717095
          Length = 900

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 486 AAVLLLH 492
>XP_006717094
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 655 AAVLLLH 661
>XP_005251923
          Length = 1069

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 655 AAVLLLH 661
>XP_006715156
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G+V+ LLH
Sbjct: 119 GSVIQLLH 126
>XP_006715155
          Length = 1850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G+V+ LLH
Sbjct: 119 GSVIQLLH 126
>XP_006715154
          Length = 2700

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   GAVVLLLH 8
           G+V+ LLH
Sbjct: 119 GSVIQLLH 126
>XP_006715065
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 106 AVVFLLH 112
>XP_006715064
          Length = 454

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           AVV LLH
Sbjct: 263 AVVFLLH 269
>XP_006711756
          Length = 985

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 627 AAVLLLH 633
>XP_005245738
          Length = 1014

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 590 AAVLLLH 596
>XP_006711755
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 627 AAVLLLH 633
>XP_005245737
          Length = 1051

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   AVVLLLH 8
           A VLLLH
Sbjct: 627 AAVLLLH 633
>XP_005270918
          Length = 592

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  GAVVLLLH 8
          G  +LLLH
Sbjct: 9  GTCILLLH 16
>NP_569736
          Length = 163

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  GAVVLLLHF 9
          GA++  LHF
Sbjct: 44 GAMIAPLHF 52
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.161    0.488 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 435,041
Number of extensions: 785
Number of successful extensions: 69
Number of sequences better than 10000.0: 69
Number of HSP's gapped: 69
Number of HSP's successfully gapped: 69
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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