Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001277144                                                           18    1135
NP_001277143                                                           18    1135
NP_001319                                                              18    1135
NP_001012632                                                           18    1135
NP_001077383                                                           18    1135
NP_001320                                                              18    1135
NP_073713                                                              18    1135
XP_005269629                                                           18    1135
XP_005269628                                                           18    1135
XP_005269627                                                           18    1135
XP_005269626                                                           18    1135
XP_006717706                                                           18    1135
XP_005269625                                                           18    1135
XP_005269624                                                           18    1135
XP_006717705                                                           18    1135
XP_005269622                                                           18    1135
XP_005269621                                                           18    1135
XP_006717704                                                           18    1135
XP_005269619                                                           18    1135
XP_005269618                                                           18    1135
XP_005272320                                                           18    1135
XP_005272319                                                           18    1135
XP_005272318                                                           18    1135
NP_005551                                                              17    2528
XP_006723861                                                           17    2528
XP_006723860                                                           17    2528
XP_006723859                                                           17    2528
NP_004371                                                              17    3301
NP_001073315                                                           17    3301
XP_005255182                                                           17    3301
XP_006720911                                                           17    3301
XP_005255181                                                           17    3301
NP_079023                                                              17    4312
NP_065816                                                              16    7355
NP_079034                                                              16    7355
XP_006710573                                                           16    7355
XP_006710572                                                           16    7355
XP_006710571                                                           16    7355
XP_006710570                                                           16    7355
XP_006710569                                                           16    7355
XP_006710568                                                           16    7355
XP_006710567                                                           16    7355
XP_006710566                                                           16    7355
XP_005245859                                                           16    7355
NP_060030                                                              16    7355
NP_060796                                                              15    9605
NP_848927                                                              15    9605
NP_851853                                                              15    9605
NP_001123620                                                           15    9605
NP_001123619                                                           15    9605
NP_695006                                                              15    9605
NP_056189                                                              15    9605
NP_001186509                                                           15    9605
NP_002855                                                              15    9605
NP_001186508                                                           15    9605
XP_005261558                                                           15    9605
XP_005261557                                                           15    9605
XP_005251157                                                           15    9605
XP_005251156                                                           15    9605
XP_005251155                                                           15    9605
XP_005250075                                                           15    9605
XP_005250074                                                           15    9605
XP_005245556                                                           15    9605
XP_005270805                                                           15    9605
NP_115734                                                              15    9605
NP_001123618                                                           15    9605
NP_001025041                                                           15    9605
>NP_001277144
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>NP_001277143
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>NP_001319
          Length = 440

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 168 GAARIRGET 176
>NP_001012632
          Length = 429

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 157 GAARIRGET 165
>NP_001077383
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>NP_001320
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>NP_073713
          Length = 985

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 714 GAARIRGET 722
>XP_005269629
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269628
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269627
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269626
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_006717706
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269625
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269624
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_006717705
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269622
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269621
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_006717704
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269619
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005269618
          Length = 445

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 174 GAARIRGET 182
>XP_005272320
          Length = 430

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 157 GAARIRGET 165
>XP_005272319
          Length = 430

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 157 GAARIRGET 165
>XP_005272318
          Length = 441

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   GAARIREET 9
           GAARIR ET
Sbjct: 168 GAARIRGET 176
>NP_005551
          Length = 3695

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  GAARIREE 8
          GAAR REE
Sbjct: 31 GAARAREE 38
>XP_006723861
          Length = 2300

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  GAARIREE 8
          GAAR REE
Sbjct: 31 GAARAREE 38
>XP_006723860
          Length = 2586

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  GAARIREE 8
          GAAR REE
Sbjct: 31 GAARAREE 38
>XP_006723859
          Length = 3700

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  GAARIREE 8
          GAAR REE
Sbjct: 31 GAARAREE 38
>NP_004371
          Length = 2442

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    GAARIREET 9
            GA++++EET
Sbjct: 1028 GASQVKEET 1036
>NP_001073315
          Length = 2404

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GAARIREET 9
           GA++++EET
Sbjct: 990 GASQVKEET 998
>XP_005255182
          Length = 2303

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   GAARIREET 9
           GA++++EET
Sbjct: 889 GASQVKEET 897
>XP_006720911
          Length = 2355

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    GAARIREET 9
            GA++++EET
Sbjct: 1028 GASQVKEET 1036
>XP_005255181
          Length = 2427

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1    GAARIREET 9
            GA++++EET
Sbjct: 1013 GASQVKEET 1021
>NP_079023
          Length = 775

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  GAARIRE 7
          GAAR+RE
Sbjct: 18 GAARLRE 24
>NP_065816
          Length = 5183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3917 GAAAMREE 3924
>NP_079034
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   GAARIREET 9
           G  RIREE+
Sbjct: 93  GPRRIREES 101
>XP_006710573
          Length = 5177

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3911 GAAAMREE 3918
>XP_006710572
          Length = 5188

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3922 GAAAMREE 3929
>XP_006710571
          Length = 5194

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3928 GAAAMREE 3935
>XP_006710570
          Length = 5195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3929 GAAAMREE 3936
>XP_006710569
          Length = 5212

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3946 GAAAMREE 3953
>XP_006710568
          Length = 5221

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3955 GAAAMREE 3962
>XP_006710567
          Length = 5222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3956 GAAAMREE 3963
>XP_006710566
          Length = 5222

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3956 GAAAMREE 3963
>XP_005245859
          Length = 5223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    GAARIREE 8
            GAA +REE
Sbjct: 3957 GAAAMREE 3964
>NP_060030
          Length = 659

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  GAARIREET 9
          GA+ I EET
Sbjct: 74 GASEIAEET 82
>NP_060796
          Length = 329

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 253 ARIREE 258
>NP_848927
          Length = 582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GAARIRE 7
          G+AR+RE
Sbjct: 17 GSARLRE 23
>NP_851853
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  GAARIREE 8
          G AR+R+E
Sbjct: 40 GEARLRDE 47
>NP_001123620
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 343 ARIREE 348
>NP_001123619
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 343 ARIREE 348
>NP_695006
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AARIREET 9
           AARI EE+
Sbjct: 456 AARIEEES 463
>NP_056189
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AARIREE 8
           AARI+EE
Sbjct: 352 AARIQEE 358
>NP_001186509
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AARIREE 8
           AARI+EE
Sbjct: 352 AARIQEE 358
>NP_002855
          Length = 1482

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 320 ARIREE 325
>NP_001186508
          Length = 738

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AARIREE 8
           AARI+EE
Sbjct: 373 AARIQEE 379
>XP_005261558
          Length = 717

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AARIREE 8
           AARI+EE
Sbjct: 352 AARIQEE 358
>XP_005261557
          Length = 752

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   AARIREE 8
           AARI+EE
Sbjct: 387 AARIQEE 393
>XP_005251157
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GAARIRE 7
          G+AR+RE
Sbjct: 17 GSARLRE 23
>XP_005251156
          Length = 549

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GAARIRE 7
          G+AR+RE
Sbjct: 17 GSARLRE 23
>XP_005251155
          Length = 560

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  GAARIRE 7
          G+AR+RE
Sbjct: 17 GSARLRE 23
>XP_005250075
          Length = 190

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 114 ARIREE 119
>XP_005250074
          Length = 343

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 267 ARIREE 272
>XP_005245556
          Length = 933

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   GAARIREET 9
           G  R+REE+
Sbjct: 560 GIIRVREES 568
>XP_005270805
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   AARIREET 9
           AARI EE+
Sbjct: 456 AARIEEES 463
>NP_115734
          Length = 488

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 375 ARIREE 380
>NP_001123618
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ARIREE 8
           ARIREE
Sbjct: 343 ARIREE 348
>NP_001025041
          Length = 793

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   GAARIREE 8
           GA+R REE
Sbjct: 236 GASREREE 243
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.310    0.126    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,756
Number of extensions: 664
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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