Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     869
NP_001075109                                                           19     869
NP_006198                                                              16    5631
NP_001268885                                                           16    7355
NP_078907                                                              16    7355
NP_115686                                                              16    7355
XP_006726062                                                           16    7355
XP_006725547                                                           16    7355
XP_005271733                                                           16    7355
XP_006718971                                                           16    7355
XP_006718969                                                           16    7355
XP_006718968                                                           16    7355
XP_005271730                                                           16    7355
XP_005252330                                                           16    7355
XP_005264256                                                           16    7355
XP_006712028                                                           16    7355
NP_938017                                                              16    7355
NP_002113                                                              15    9605
NP_055726                                                              15    9605
NP_000048                                                              15    9605
NP_001274177                                                           15    9605
NP_001274176                                                           15    9605
NP_001274175                                                           15    9605
NP_064440                                                              15    9605
NP_001193830                                                           15    9605
NP_060015                                                              15    9605
NP_001073333                                                           15    9605
XP_005275601                                                           15    9605
XP_005275599                                                           15    9605
XP_005275390                                                           15    9605
XP_003846516                                                           15    9605
XP_005275165                                                           15    9605
XP_005275010                                                           15    9605
XP_006720695                                                           15    9605
XP_005249957                                                           15    9605
XP_006715142                                                           15    9605
XP_005246685                                                           15    9605
XP_005246683                                                           15    9605
XP_005276137                                                           15    9605
XP_003120317                                                           15    9605
NP_006015                                                              15    9605
NP_009007                                                              15    9605
>NP_008835
          Length = 4128

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FYKLLYITV 9
           FYKLL ITV
Sbjct: 666 FYKLLSITV 674
>NP_001075109
          Length = 4097

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FYKLLYITV 9
           FYKLL ITV
Sbjct: 666 FYKLLSITV 674
>NP_006198
          Length = 375

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   YKLLYITV 9
           Y+LLY+ V
Sbjct: 260 YQLLYVAV 267
>NP_001268885
          Length = 3631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FYKLLY 6
            FYKLL+
Sbjct: 2720 FYKLLF 2725
>NP_078907
          Length = 507

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FYKLLYITV 9
           +YK L IT+
Sbjct: 320 YYKFLEITI 328
>NP_115686
          Length = 183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  FYKLLYI 7
          FY+ LYI
Sbjct: 80 FYRALYI 86
>XP_006726062
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FYKLLYITV 9
           F+K+ Y+T+
Sbjct: 170 FFKISYLTL 178
>XP_006725547
          Length = 254

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1   FYKLLYITV 9
           F+K+ Y+T+
Sbjct: 170 FFKISYLTL 178
>XP_005271733
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FYKLLYITV 9
           +YK L IT+
Sbjct: 142 YYKFLEITI 150
>XP_006718971
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FYKLLYITV 9
           +YK L IT+
Sbjct: 142 YYKFLEITI 150
>XP_006718969
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FYKLLYITV 9
           +YK L IT+
Sbjct: 142 YYKFLEITI 150
>XP_006718968
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FYKLLYITV 9
           +YK L IT+
Sbjct: 142 YYKFLEITI 150
>XP_005271730
          Length = 648

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FYKLLYITV 9
           +YK L IT+
Sbjct: 461 YYKFLEITI 469
>XP_005252330
          Length = 163

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1  FYKLLYI 7
          FY+ LYI
Sbjct: 80 FYRALYI 86
>XP_005264256
          Length = 113

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FYKLLYITV 9
          +YK + ITV
Sbjct: 75 YYKFIVITV 83
>XP_006712028
          Length = 183

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FYKLLYITV 9
          +YK + ITV
Sbjct: 75 YYKFIVITV 83
>NP_938017
          Length = 198

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FYKLLYITV 9
          +YK + ITV
Sbjct: 75 YYKFIVITV 83
>NP_002113
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>NP_055726
          Length = 961

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   YKLLYITV 9
           YKL Y T+
Sbjct: 253 YKLCYFTL 260
>NP_000048
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLLYIT 8
           KLLY+T
Sbjct: 761 KLLYVT 766
>NP_001274177
          Length = 1042

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLLYIT 8
           KLLY+T
Sbjct: 386 KLLYVT 391
>NP_001274176
          Length = 1286

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLLYIT 8
           KLLY+T
Sbjct: 761 KLLYVT 766
>NP_001274175
          Length = 1417

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLLYIT 8
           KLLY+T
Sbjct: 761 KLLYVT 766
>NP_064440
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>NP_001193830
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FYKLLYIT 8
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>NP_060015
          Length = 370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   YKLLYITV 9
           YK +++TV
Sbjct: 152 YKAIFVTV 159
>NP_001073333
          Length = 747

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FYKLLYIT 8
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>XP_005275601
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005275599
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005275390
          Length = 208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_003846516
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005275165
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_005275010
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_006720695
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLLYIT 8
           KLLY+T
Sbjct: 107 KLLYVT 112
>XP_005249957
          Length = 682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FYKLLYIT 8
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>XP_006715142
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 171 FFKISYLT 178
>XP_005246685
          Length = 354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YKLLYITV 9
          Y+LL ITV
Sbjct: 4  YRLLSITV 11
>XP_005246683
          Length = 387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  YKLLYITV 9
          Y+LL ITV
Sbjct: 4  YRLLSITV 11
>XP_005276137
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>XP_003120317
          Length = 254

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1   FYKLLYIT 8
           F+K+ Y+T
Sbjct: 170 FFKISYLT 177
>NP_006015
          Length = 789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FYKLLYIT 8
           FY+  Y+T
Sbjct: 99  FYQFCYVT 106
>NP_009007
          Length = 458

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   YKLLYI 7
           YKL+YI
Sbjct: 357 YKLVYI 362
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.345    0.162    0.483 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 468,368
Number of extensions: 867
Number of successful extensions: 42
Number of sequences better than 10000.0: 42
Number of HSP's gapped: 42
Number of HSP's successfully gapped: 42
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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