Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005091                                                              20     390
NP_653080                                                              20     390
XP_005267292                                                           20     390
XP_005267291                                                           20     390
XP_005267290                                                           20     390
NP_957719                                                              17    3301
NP_061004                                                              17    3301
NP_003863                                                              17    3301
NP_958436                                                              17    3301
NP_957718                                                              17    3301
NP_001186064                                                           17    3301
NP_004171                                                              17    3301
XP_005246991                                                           17    3301
XP_005246990                                                           17    3301
XP_005246268                                                           17    3301
XP_005246267                                                           17    3301
XP_005246265                                                           17    3301
XP_005246264                                                           17    3301
XP_005246263                                                           17    3301
NP_001182728                                                           17    4312
NP_001182727                                                           17    4312
NP_000518                                                              17    4312
NP_001182732                                                           17    4312
NP_001182729                                                           17    4312
NP_000101                                                              16    5631
NP_775082                                                              16    5631
NP_003377                                                              16    5631
NP_078966                                                              16    5631
NP_005821                                                              16    5631
NP_001121182                                                           16    5631
NP_001121181                                                           16    5631
NP_001121180                                                           16    5631
NP_005798                                                              16    5631
XP_005244879                                                           16    5631
XP_006711171                                                           16    5631
XP_006710460                                                           16    5631
XP_005270619                                                           16    5631
NP_001073950                                                           16    7355
NP_001186363                                                           16    7355
XP_005267232                                                           16    7355
XP_005267230                                                           16    7355
XP_005267229                                                           16    7355
XP_005267228                                                           16    7355
XP_005267227                                                           16    7355
XP_005267226                                                           16    7355
NP_057185                                                              16    7355
NP_783864                                                              15    9605
XP_006715416                                                           15    9605
XP_006715415                                                           15    9605
XP_005266895                                                           15    9605
XP_005262701                                                           15    9605
XP_003846779                                                           15    9605
>NP_005091
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVRTEETTT 9
            FVRTEET T
Sbjct: 1561 FVRTEETAT 1569
>NP_653080
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVRTEETTT 9
            FVRTEET T
Sbjct: 1463 FVRTEETAT 1471
>XP_005267292
          Length = 1677

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVRTEETTT 9
            FVRTEET T
Sbjct: 1456 FVRTEETAT 1464
>XP_005267291
          Length = 1684

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVRTEETTT 9
            FVRTEET T
Sbjct: 1463 FVRTEETAT 1471
>XP_005267290
          Length = 1782

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVRTEETTT 9
            FVRTEET T
Sbjct: 1561 FVRTEETAT 1569
>NP_957719
          Length = 901

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>NP_061004
          Length = 906

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>NP_003863
          Length = 926

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>NP_958436
          Length = 909

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>NP_957718
          Length = 931

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>NP_001186064
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 280 FVKTEET 286
>NP_004171
          Length = 425

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 280 FVKTEET 286
>XP_005246991
          Length = 931

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>XP_005246990
          Length = 931

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   VRTEETTT 9
           V++EETTT
Sbjct: 608 VKSEETTT 615
>XP_005246268
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 281 FVKTEET 287
>XP_005246267
          Length = 426

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 281 FVKTEET 287
>XP_005246265
          Length = 484

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 339 FVKTEET 345
>XP_005246264
          Length = 532

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 387 FVKTEET 393
>XP_005246263
          Length = 533

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV+TEET
Sbjct: 388 FVKTEET 394
>NP_001182728
          Length = 819

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           VRT+ TTT
Sbjct: 695 VRTQHTTT 702
>NP_001182727
          Length = 858

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           VRT+ TTT
Sbjct: 736 VRTQHTTT 743
>NP_000518
          Length = 860

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           VRT+ TTT
Sbjct: 736 VRTQHTTT 743
>NP_001182732
          Length = 682

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           VRT+ TTT
Sbjct: 558 VRTQHTTT 565
>NP_001182729
          Length = 692

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           VRT+ TTT
Sbjct: 568 VRTQHTTT 575
>NP_000101
          Length = 1025

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FVRTEETTT 9
           FVRTE+  T
Sbjct: 408 FVRTEQDET 416
>NP_775082
          Length = 2721

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TEETTT 9
           TEETTT
Sbjct: 665 TEETTT 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TEETTT 9
           TEETTT
Sbjct: 826 TEETTT 831
>NP_003377
          Length = 2812

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TEETTT 9
           TEETTT
Sbjct: 665 TEETTT 670

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   TEETTT 9
           TEETTT
Sbjct: 826 TEETTT 831
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FVRTEETTT 9
            F  +EETTT
Sbjct: 5897 FPHSEETTT 5905
>NP_005821
          Length = 395

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  VRTEETT 8
          VRTEET+
Sbjct: 75 VRTEETS 81
>NP_001121182
          Length = 1270

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           V T+ETTT
Sbjct: 150 VETKETTT 157
>NP_001121181
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           V T+ETTT
Sbjct: 191 VETKETTT 198
>NP_001121180
          Length = 1363

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           V T+ETTT
Sbjct: 243 VETKETTT 250
>NP_005798
          Length = 1404

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           V T+ETTT
Sbjct: 284 VETKETTT 291
>XP_005244879
          Length = 1361

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           V T+ETTT
Sbjct: 241 VETKETTT 248
>XP_006711171
          Length = 1381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           V T+ETTT
Sbjct: 284 VETKETTT 291
>XP_006710460
          Length = 889

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FVRTEETTT 9
           FVRTE+  T
Sbjct: 408 FVRTEQDET 416
>XP_005270619
          Length = 953

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FVRTEETTT 9
           FVRTE+  T
Sbjct: 408 FVRTEQDET 416
>NP_001073950
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 305 VRTEET 310
>NP_001186363
          Length = 133

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FVRTEETTT 9
           +VR EET T
Sbjct: 125 YVRHEETLT 133
>XP_005267232
          Length = 437

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 305 VRTEET 310
>XP_005267230
          Length = 649

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 140 VRTEET 145
>XP_005267229
          Length = 721

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 305 VRTEET 310
>XP_005267228
          Length = 813

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 304 VRTEET 309
>XP_005267227
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 305 VRTEET 310
>XP_005267226
          Length = 814

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VRTEET 7
           VRTEET
Sbjct: 305 VRTEET 310
>NP_057185
          Length = 180

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FVRTEETTT 9
           +VR EET T
Sbjct: 172 YVRHEETLT 180
>NP_783864
          Length = 1044

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VRTEETT 8
           V+TE+TT
Sbjct: 425 VKTEDTT 431
>XP_006715416
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV++EET
Sbjct: 480 FVKSEET 486
>XP_006715415
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV++EET
Sbjct: 480 FVKSEET 486
>XP_005266895
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVRTEET 7
           FV++EET
Sbjct: 480 FVKSEET 486
>XP_005262701
          Length = 1035

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VRTEETT 8
           V+TE+TT
Sbjct: 425 VKTEDTT 431
>XP_003846779
          Length = 914

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   VRTEETTT 9
           +RT ETT+
Sbjct: 142 IRTTETTS 149
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.309    0.117    0.298 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 440,933
Number of extensions: 609
Number of successful extensions: 54
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 54
Number of HSP's successfully gapped: 54
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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