Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           19     665
NP_001185763                                                           19     665
NP_055459                                                              19     665
XP_006711719                                                           19     665
XP_006711718                                                           19     665
XP_006711717                                                           19     665
XP_006711716                                                           19     665
XP_006711715                                                           19     665
XP_006711714                                                           19     665
XP_006711713                                                           19     665
XP_006711712                                                           19     665
XP_006711711                                                           19     665
XP_006711710                                                           19     665
XP_006711709                                                           19     665
XP_005277503                                                           19     665
XP_005273038                                                           19     665
XP_006711708                                                           19     665
XP_005277500                                                           19     665
XP_006711707                                                           19     665
XP_005277499                                                           19     665
XP_006711706                                                           19     665
XP_006711705                                                           19     665
XP_006710143                                                           19     665
XP_006710142                                                           19     665
XP_006710141                                                           19     665
NP_872357                                                              18    1935
XP_006726410                                                           18    1935
XP_005264301                                                           18    1935
XP_006711164                                                           18    1935
NP_006559                                                              17    3301
XP_005271769                                                           17    4312
NP_116262                                                              17    4312
NP_079382                                                              16    5631
NP_055068                                                              16    7355
NP_001156750                                                           16    7355
NP_001156751                                                           16    7355
NP_055754                                                              16    7355
XP_006724788                                                           16    7355
XP_005258292                                                           16    7355
XP_006722483                                                           16    7355
XP_005258291                                                           16    7355
XP_005258290                                                           16    7355
XP_006720987                                                           16    7355
NP_001136272                                                           15    9605
NP_001269889                                                           15    9605
NP_037407                                                              15    9605
NP_001269888                                                           15    9605
NP_060707                                                              15    9605
NP_075053                                                              15    9605
NP_001243112                                                           15    9605
NP_001243111                                                           15    9605
NP_059984                                                              15    9605
XP_006724893                                                           15    9605
XP_005274763                                                           15    9605
XP_006724892                                                           15    9605
XP_006722374                                                           15    9605
XP_006722373                                                           15    9605
XP_006722370                                                           15    9605
XP_006722365                                                           15    9605
XP_006721247                                                           15    9605
XP_006721246                                                           15    9605
XP_006721245                                                           15    9605
XP_006721244                                                           15    9605
XP_006719964                                                           15    9605
XP_006719963                                                           15    9605
XP_006719962                                                           15    9605
XP_006719961                                                           15    9605
XP_006719960                                                           15    9605
XP_005266656                                                           15    9605
XP_006714735                                                           15    9605
XP_005248626                                                           15    9605
NP_004285                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1217 VKQDSKQI 1224
>NP_001185763
          Length = 2362

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1261 VKQDSKQI 1268
>NP_055459
          Length = 2346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1261 VKQDSKQI 1268
>XP_006711719
          Length = 2302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1217 VKQDSKQI 1224
>XP_006711718
          Length = 1436

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VKQDSKQI 9
           VKQDSKQI
Sbjct: 268 VKQDSKQI 275
>XP_006711717
          Length = 2385

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1217 VKQDSKQI 1224
>XP_006711716
          Length = 2411

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1326 VKQDSKQI 1333
>XP_006711715
          Length = 2428

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1260 VKQDSKQI 1267
>XP_006711714
          Length = 2429

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1261 VKQDSKQI 1268
>XP_006711713
          Length = 2432

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1264 VKQDSKQI 1271
>XP_006711712
          Length = 2473

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_006711711
          Length = 2482

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1314 VKQDSKQI 1321
>XP_006711710
          Length = 2494

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1326 VKQDSKQI 1333
>XP_006711709
          Length = 2495

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1327 VKQDSKQI 1334
>XP_005277503
          Length = 2498

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_005273038
          Length = 2509

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_006711708
          Length = 2512

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_005277500
          Length = 2525

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_006711707
          Length = 2553

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_005277499
          Length = 2561

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_006711706
          Length = 2591

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1423 VKQDSKQI 1430
>XP_006711705
          Length = 2592

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDSKQI
Sbjct: 1424 VKQDSKQI 1431
>XP_006710143
          Length = 562

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VKQDSKQI 9
           VKQDSKQI
Sbjct: 103 VKQDSKQI 110
>XP_006710142
          Length = 671

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VKQDSKQI 9
           VKQDSKQI
Sbjct: 212 VKQDSKQI 219
>XP_006710141
          Length = 672

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   VKQDSKQI 9
           VKQDSKQI
Sbjct: 213 VKQDSKQI 220
>NP_872357
          Length = 414

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  FVKQDSK 7
          F+KQDSK
Sbjct: 28 FIKQDSK 34
>XP_006726410
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDS+QI
Sbjct: 1064 VKQDSEQI 1071
>XP_005264301
          Length = 414

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  FVKQDSK 7
          F+KQDSK
Sbjct: 28 FIKQDSK 34
>XP_006711164
          Length = 2087

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2    VKQDSKQI 9
            VKQDS+QI
Sbjct: 1064 VKQDSEQI 1071
>NP_006559
          Length = 332

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FVKQDSKQ 8
           F+K+DSK+
Sbjct: 141 FIKKDSKE 148
>XP_005271769
          Length = 677

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           FVK+DS ++
Sbjct: 204 FVKEDSAEV 212
>NP_116262
          Length = 649

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           FVK+DS ++
Sbjct: 176 FVKEDSAEV 184
>NP_079382
          Length = 273

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FVKQDSKQI 9
          FVK+D K I
Sbjct: 66 FVKEDDKLI 74
>NP_055068
          Length = 2725

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VKQDSK 7
           VKQDSK
Sbjct: 469 VKQDSK 474
>NP_001156750
          Length = 2732

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VKQDSK 7
           VKQDSK
Sbjct: 469 VKQDSK 474
>NP_001156751
          Length = 2731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VKQDSK 7
           VKQDSK
Sbjct: 468 VKQDSK 473
>NP_055754
          Length = 1435

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FVKQDSKQI 9
            +V +DSKQ+
Sbjct: 1247 YVVEDSKQL 1255
>XP_006724788
          Length = 2570

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   VKQDSK 7
           VKQDSK
Sbjct: 315 VKQDSK 320
>XP_005258292
          Length = 1161

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           +V +DSKQ+
Sbjct: 973 YVVEDSKQL 981
>XP_006722483
          Length = 1338

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FVKQDSKQI 9
            +V +DSKQ+
Sbjct: 1248 YVVEDSKQL 1256
>XP_005258291
          Length = 1406

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FVKQDSKQI 9
            +V +DSKQ+
Sbjct: 1248 YVVEDSKQL 1256
>XP_005258290
          Length = 1436

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FVKQDSKQI 9
            +V +DSKQ+
Sbjct: 1248 YVVEDSKQL 1256
>XP_006720987
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   KQDSKQI 9
           +QDSKQ+
Sbjct: 357 EQDSKQV 363
>NP_001136272
          Length = 3144

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    FVKQDSKQI 9
            +VKQDS  +
Sbjct: 1922 YVKQDSNLV 1930
>NP_001269889
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VKQDSKQI 9
            VKQ+SK +
Sbjct: 996  VKQESKDV 1003
>NP_037407
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 881 VKEDSKE 887
>NP_001269888
          Length = 1135

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VKQDSKQI 9
            VKQ+SK +
Sbjct: 996  VKQESKDV 1003
>NP_060707
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    VKQDSKQI 9
            VKQ+SK +
Sbjct: 1011 VKQESKDV 1018
>NP_075053
          Length = 765

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FVKQDSKQI 9
           F+K+  KQI
Sbjct: 402 FIKESLKQI 410
>NP_001243112
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 881 VKEDSKE 887
>NP_001243111
          Length = 2663

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 881 VKEDSKE 887
>NP_059984
          Length = 1871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           FV++D+K I
Sbjct: 977 FVRRDAKAI 985
>XP_006724893
          Length = 1719

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           FV++D+K I
Sbjct: 977 FVRRDAKAI 985
>XP_005274763
          Length = 1789

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           FV++D+K I
Sbjct: 895 FVRRDAKAI 903
>XP_006724892
          Length = 1841

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FVKQDSKQI 9
           FV++D+K I
Sbjct: 947 FVRRDAKAI 955
>XP_006722374
          Length = 944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           +K+DSKQ
Sbjct: 743 LKEDSKQ 749
>XP_006722373
          Length = 948

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           +K+DSKQ
Sbjct: 747 LKEDSKQ 753
>XP_006722370
          Length = 956

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           +K+DSKQ
Sbjct: 755 LKEDSKQ 761
>XP_006722365
          Length = 981

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           +K+DSKQ
Sbjct: 780 LKEDSKQ 786
>XP_006721247
          Length = 2564

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 782 VKEDSKE 788
>XP_006721246
          Length = 2620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 838 VKEDSKE 844
>XP_006721245
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 847 VKEDSKE 853
>XP_006721244
          Length = 2629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   VKQDSKQ 8
           VK+DSK+
Sbjct: 847 VKEDSKE 853
>XP_006719964
          Length = 444

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
>XP_006719963
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
>XP_006719962
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
>XP_006719961
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
>XP_006719960
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
>XP_005266656
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
>XP_006714735
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FVKQDSKQI 9
           F+K+  KQI
Sbjct: 402 FIKESLKQI 410
>XP_005248626
          Length = 724

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FVKQDSKQI 9
           F+K+  KQI
Sbjct: 361 FIKESLKQI 369
>NP_004285
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KQDSKQI 9
           KQD KQ+
Sbjct: 142 KQDEKQL 148
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.319    0.131    0.331 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 531,816
Number of extensions: 841
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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