Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001245210                                                           17    4312
NP_000242                                                              17    4312
XP_005264389                                                           17    4312
NP_000074                                                              16    5631
NP_002179                                                              16    5631
NP_001277675                                                           16    7355
NP_001180575                                                           16    7355
NP_036200                                                              16    7355
NP_001002021                                                           16    7355
NP_002617                                                              16    7355
XP_005261194                                                           16    7355
XP_005261193                                                           16    7355
XP_005261192                                                           16    7355
XP_006724075                                                           16    7355
XP_006724074                                                           16    7355
NP_001106964                                                           15    9605
NP_001106963                                                           15    9605
NP_001106965                                                           15    9605
NP_006631                                                              15    9605
NP_001106968                                                           15    9605
NP_001106967                                                           15    9605
NP_001106966                                                           15    9605
NP_006054                                                              15    9605
NP_038478                                                              15    9605
NP_001276904                                                           15    9605
NP_038477                                                              15    9605
NP_112598                                                              15    9605
XP_006721707                                                           15    9605
XP_005257019                                                           15    9605
XP_005257018                                                           15    9605
XP_005257017                                                           15    9605
XP_005257016                                                           15    9605
XP_006721706                                                           15    9605
XP_006719271                                                           15    9605
XP_005268661                                                           15    9605
XP_005268660                                                           15    9605
XP_005268659                                                           15    9605
XP_005268657                                                           15    9605
XP_006719270                                                           15    9605
XP_005268656                                                           15    9605
XP_005268654                                                           15    9605
XP_005268653                                                           15    9605
XP_006712537                                                           15    9605
XP_006712536                                                           15    9605
XP_005246557                                                           15    9605
XP_006712535                                                           15    9605
XP_006712534                                                           15    9605
XP_006712533                                                           15    9605
XP_006712532                                                           15    9605
XP_006712531                                                           15    9605
XP_006712530                                                           15    9605
XP_006712529                                                           15    9605
XP_006712528                                                           15    9605
XP_006712527                                                           15    9605
XP_005246549                                                           15    9605
XP_006712526                                                           15    9605
XP_006712525                                                           15    9605
XP_005246546                                                           15    9605
XP_006712524                                                           15    9605
XP_005246545                                                           15    9605
>NP_001245210
          Length = 868

 Score = 16.5 bits (31), Expect =  4312
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1  FVKD-LLVRQ 9
          FVKD LLVRQ
Sbjct: 22 FVKDLLLVRQ 31
>NP_000242
          Length = 934

 Score = 16.5 bits (31), Expect =  4312
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1  FVKD-LLVRQ 9
          FVKD LLVRQ
Sbjct: 88 FVKDLLLVRQ 97
>XP_005264389
          Length = 921

 Score = 16.5 bits (31), Expect =  4312
 Identities = 9/10 (90%), Positives = 9/10 (90%), Gaps = 1/10 (10%)

Query: 1  FVKD-LLVRQ 9
          FVKD LLVRQ
Sbjct: 88 FVKDLLLVRQ 97
>NP_000074
          Length = 988

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           FV+D++VR
Sbjct: 604 FVEDIMVR 611
>NP_002179
          Length = 146

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FVKDLLV 7
           FVKDLL+
Sbjct: 128 FVKDLLL 134
>NP_001277675
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVKDLLV 7
           +VKDLL+
Sbjct: 263 YVKDLLI 269
>NP_001180575
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVKDLLV 7
           +VKDLL+
Sbjct: 263 YVKDLLI 269
>NP_036200
          Length = 282

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVKDLLV 7
           +VKDLL+
Sbjct: 263 YVKDLLI 269
>NP_001002021
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 328 YVKDLVVQR 336
>NP_002617
          Length = 780

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 278 YVKDLVVQR 286
>XP_005261194
          Length = 751

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 249 YVKDLVVQR 257
>XP_005261193
          Length = 774

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 272 YVKDLVVQR 280
>XP_005261192
          Length = 803

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 301 YVKDLVVQR 309
>XP_006724075
          Length = 830

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 328 YVKDLVVQR 336
>XP_006724074
          Length = 853

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FVKDLLVRQ 9
           +VKDL+V++
Sbjct: 351 YVKDLVVQR 359
>NP_001106964
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 371 YLRDLLIR 378
>NP_001106963
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 535 YLRDLLIR 542
>NP_001106965
          Length = 579

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 528 YLRDLLIR 535
>NP_006631
          Length = 568

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 517 YLRDLLIR 524
>NP_001106968
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 284 YLRDLLIR 291
>NP_001106967
          Length = 474

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 423 YLRDLLIR 430
>NP_001106966
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 371 YLRDLLIR 378
>NP_006054
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FVKDLLV 7
           FVKDL++
Sbjct: 301 FVKDLIL 307
>NP_038478
          Length = 2168

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1135 VQDLLVR 1141
>NP_001276904
          Length = 2132

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1099 VQDLLVR 1105
>NP_038477
          Length = 1905

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 896 VQDLLVR 902
>NP_112598
          Length = 5088

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 1669 KDLIVRE 1675

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 2327 KDLIVRE 2333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 2863 KDLIVRE 2869

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 3394 KDLIVRE 3400

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 3928 KDLIVRE 3934

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 4462 KDLIVRE 4468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    KDLLVRQ 9
            KDL+VR+
Sbjct: 4995 KDLIVRE 5001
>XP_006721707
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 284 YLRDLLIR 291
>XP_005257019
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 284 YLRDLLIR 291
>XP_005257018
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 284 YLRDLLIR 291
>XP_005257017
          Length = 335

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 284 YLRDLLIR 291
>XP_005257016
          Length = 362

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 311 YLRDLLIR 318
>XP_006721706
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 1   FVKDLLVR 8
           +++DLL+R
Sbjct: 371 YLRDLLIR 378
>XP_006719271
          Length = 1555

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 915 VQDLLVR 921
>XP_005268661
          Length = 1657

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 648 VQDLLVR 654
>XP_005268660
          Length = 1875

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 866 VQDLLVR 872
>XP_005268659
          Length = 1894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 885 VQDLLVR 891
>XP_005268657
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 894 VQDLLVR 900
>XP_006719270
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 894 VQDLLVR 900
>XP_005268656
          Length = 1903

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 894 VQDLLVR 900
>XP_005268654
          Length = 1923

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 915 VQDLLVR 921
>XP_005268653
          Length = 1924

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   VKDLLVR 8
           V+DLLVR
Sbjct: 915 VQDLLVR 921
>XP_006712537
          Length = 1952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152
>XP_006712536
          Length = 2082

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1014 VQDLLVR 1020
>XP_005246557
          Length = 2095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1027 VQDLLVR 1033
>XP_006712535
          Length = 2095

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1027 VQDLLVR 1033
>XP_006712534
          Length = 2114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1046 VQDLLVR 1052
>XP_006712533
          Length = 2116

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1048 VQDLLVR 1054
>XP_006712532
          Length = 2141

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1108 VQDLLVR 1114
>XP_006712531
          Length = 2169

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1101 VQDLLVR 1107
>XP_006712530
          Length = 2176

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1108 VQDLLVR 1114
>XP_006712529
          Length = 2179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152
>XP_006712528
          Length = 2180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1112 VQDLLVR 1118
>XP_006712527
          Length = 2203

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1135 VQDLLVR 1141
>XP_005246549
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1144 VQDLLVR 1150
>XP_006712526
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1144 VQDLLVR 1150
>XP_006712525
          Length = 2212

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1144 VQDLLVR 1150
>XP_005246546
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152
>XP_006712524
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152
>XP_005246545
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    VKDLLVR 8
            V+DLLVR
Sbjct: 1146 VQDLLVR 1152
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.156    0.419 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 472,417
Number of extensions: 760
Number of successful extensions: 66
Number of sequences better than 10000.0: 60
Number of HSP's gapped: 66
Number of HSP's successfully gapped: 66
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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