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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_008835                                                              19     665
NP_001075109                                                           19     665
NP_001073960                                                           17    4312
NP_055503                                                              17    4312
XP_006717605                                                           17    4312
NP_065820                                                              16    5631
NP_000247                                                              16    7355
NP_919442                                                              16    7355
NP_085150                                                              16    7355
XP_005259651                                                           16    7355
XP_006718301                                                           16    7355
NP_001263256                                                           15    9605
NP_001263255                                                           15    9605
NP_653186                                                              15    9605
NP_945185                                                              15    9605
NP_001136175                                                           15    9605
NP_001136176                                                           15    9605
NP_001364                                                              15    9605
NP_659441                                                              15    9605
NP_525021                                                              15    9605
NP_115544                                                              15    9605
XP_006725181                                                           15    9605
XP_006725180                                                           15    9605
XP_006718494                                                           15    9605
XP_005273799                                                           15    9605
XP_006718493                                                           15    9605
XP_006716362                                                           15    9605
XP_006716361                                                           15    9605
XP_006711798                                                           15    9605
NP_001004477                                                           15    9605

>NP_008835
          Length = 4128

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVDRSLFTL 9
            FVDRSL TL
Sbjct: 1819 FVDRSLLTL 1827



>NP_001075109
          Length = 4097

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FVDRSLFTL 9
            FVDRSL TL
Sbjct: 1819 FVDRSLLTL 1827



>NP_001073960
          Length = 845

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FVDRSLFTL 9
           F+DR+ FTL
Sbjct: 289 FLDRTPFTL 297



>NP_055503
          Length = 828

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FVDRSLFTL 9
           F+DR+ FTL
Sbjct: 272 FLDRTPFTL 280



>XP_006717605
          Length = 856

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FVDRSLFTL 9
           F+DR+ FTL
Sbjct: 300 FLDRTPFTL 308



>NP_065820
          Length = 1388

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    VDRSLFT 8
            +DRSL+T
Sbjct: 1301 IDRSLYT 1307



>NP_000247
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DRSLFTL 9
           DRS+FT+
Sbjct: 732 DRSIFTV 738



>NP_919442
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VDRSLFTL 9
          VD+ LFTL
Sbjct: 68 VDQHLFTL 75



>NP_085150
          Length = 941

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FVDRSLFT 8
           F D+SL+T
Sbjct: 594 FADQSLYT 601



>XP_005259651
          Length = 284

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  VDRSLFTL 9
          VD+ LFTL
Sbjct: 68 VDQHLFTL 75



>XP_006718301
          Length = 1268

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   DRSLFTL 9
           DRS+FT+
Sbjct: 726 DRSIFTV 732



>NP_001263256
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DRSLFT 8
           DRS+FT
Sbjct: 123 DRSIFT 128



>NP_001263255
          Length = 519

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DRSLFT 8
           DRS+FT
Sbjct: 123 DRSIFT 128



>NP_653186
          Length = 553

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DRSLFT 8
           DRS+FT
Sbjct: 123 DRSIFT 128



>NP_945185
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VDRSLFT 8
          +DRS+FT
Sbjct: 92 LDRSVFT 98



>NP_001136175
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VDRSLFT 8
          +DRS+FT
Sbjct: 62 LDRSVFT 68



>NP_001136176
          Length = 704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  VDRSLFT 8
          +DRS+FT
Sbjct: 62 LDRSVFT 68



>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FVDRSLF 7
            F D+SLF
Sbjct: 2645 FTDKSLF 2651



>NP_659441
          Length = 787

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FVDRSL 6
           F+DRSL
Sbjct: 156 FIDRSL 161



>NP_525021
          Length = 1543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FVDRSLFTL 9
           F+D S+F L
Sbjct: 932 FIDGSIFLL 940



>NP_115544
          Length = 830

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DRSLFT 8
           DRS+FT
Sbjct: 333 DRSIFT 338



>XP_006725181
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FVDRSL 6
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006725180
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FVDRSL 6
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006718494
          Length = 543

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  DRSLFT 8
          DRS+FT
Sbjct: 88 DRSIFT 93



>XP_005273799
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DRSLFT 8
           DRS+FT
Sbjct: 123 DRSIFT 128



>XP_006718493
          Length = 578

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   DRSLFT 8
           DRS+FT
Sbjct: 123 DRSIFT 128



>XP_006716362
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FVDRSL 6
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006716361
          Length = 774

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FVDRSL 6
           F+DRSL
Sbjct: 156 FIDRSL 161



>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1    FVDRSLF 7
            F D+SLF
Sbjct: 2651 FTDKSLF 2657



>NP_001004477
          Length = 326

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FVDRSLFT 8
          +VDRSL T
Sbjct: 66 WVDRSLHT 73



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.155    0.445 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,755
Number of extensions: 530
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)