Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_055645                                                              18    1135
NP_722576                                                              18    1482
XP_005262424                                                           18    1482
NP_620129                                                              17    3301
NP_001158238                                                           17    4312
NP_078997                                                              17    4312
NP_008816                                                              17    4312
XP_005256014                                                           17    4312
NP_112145                                                              16    5631
NP_058641                                                              16    5631
XP_005275584                                                           16    5631
XP_005275585                                                           16    5631
XP_005275424                                                           16    5631
XP_006726053                                                           16    5631
XP_005275425                                                           16    5631
XP_005275363                                                           16    5631
XP_005275290                                                           16    5631
XP_005275291                                                           16    5631
XP_005275240                                                           16    5631
XP_005275148                                                           16    5631
XP_006725872                                                           16    5631
XP_005275149                                                           16    5631
XP_005274994                                                           16    5631
XP_005274995                                                           16    5631
XP_005272950                                                           16    5631
XP_005272848                                                           16    5631
XP_005272849                                                           16    5631
XP_005274949                                                           16    5631
XP_005274902                                                           16    5631
XP_006725095                                                           16    5631
XP_005274903                                                           16    5631
XP_005249065                                                           16    5631
XP_005249066                                                           16    5631
NP_000114                                                              15    9605
NP_996816                                                              15    9605
NP_000085                                                              15    9605
NP_001231118                                                           15    9605
NP_001231121                                                           15    9605
NP_055564                                                              15    9605
NP_001231119                                                           15    9605
NP_001231120                                                           15    9605
NP_001231122                                                           15    9605
NP_001003698                                                           15    9605
NP_001161816                                                           15    9605
NP_001003699                                                           15    9605
NP_001003700                                                           15    9605
NP_703149                                                              15    9605
NP_001191354                                                           15    9605
XP_006720406                                                           15    9605
XP_006720404                                                           15    9605
XP_006720403                                                           15    9605
XP_006720402                                                           15    9605
XP_006720401                                                           15    9605
XP_006720400                                                           15    9605
XP_006720399                                                           15    9605
XP_006715224                                                           15    9605
XP_005249329                                                           15    9605
XP_006715223                                                           15    9605
XP_006715222                                                           15    9605
XP_005249333                                                           15    9605
XP_006715221                                                           15    9605
XP_006715220                                                           15    9605
XP_005249332                                                           15    9605
XP_006715219                                                           15    9605
>NP_055645
          Length = 712

 Score = 18.5 bits (36), Expect =  1135
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   FTQYQLTL 8
           FTQ+QLTL
Sbjct: 410 FTQWQLTL 417
>NP_722576
          Length = 3080

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FTQYQLTLL 9
            FTQ QLTLL
Sbjct: 2362 FTQDQLTLL 2370
>XP_005262424
          Length = 2875

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FTQYQLTLL 9
            FTQ QLTLL
Sbjct: 2157 FTQDQLTLL 2165
>NP_620129
          Length = 268

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2  TQYQLTLL 9
          TQY LTLL
Sbjct: 76 TQYLLTLL 83
>NP_001158238
          Length = 2789

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FTQYQLTLL 9
            FT YQL +L
Sbjct: 1335 FTDYQLRVL 1343
>NP_078997
          Length = 3616

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FTQYQLTLL 9
            FT YQL +L
Sbjct: 2233 FTDYQLRVL 2241
>NP_008816
          Length = 3703

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FTQYQLTLL 9
            FT YQL +L
Sbjct: 2249 FTDYQLRVL 2257
>XP_005256014
          Length = 3702

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FTQYQLTLL 9
            FT YQL +L
Sbjct: 2248 FTDYQLRVL 2256
>NP_112145
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>NP_058641
          Length = 291

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTQYQLTLL 9
           FT Y LT+L
Sbjct: 236 FTSYFLTIL 244
>XP_005275584
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275585
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275424
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_006726053
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275425
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275363
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275290
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275291
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275240
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275148
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_006725872
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005275149
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005274994
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005274995
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005272950
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005272848
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005272849
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005274949
          Length = 312

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005274902
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_006725095
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005274903
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005249065
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>XP_005249066
          Length = 316

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FTQYQLTLL 9
          FT Y LTL+
Sbjct: 30 FTSYLLTLV 38
>NP_000114
          Length = 1186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FTQYQL 6
           F+QYQL
Sbjct: 229 FSQYQL 234
>NP_996816
          Length = 5202

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 1    FTQYQLTL 8
            FTQY++ +
Sbjct: 3837 FTQYEIRI 3844
>NP_000085
          Length = 2944

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   TQYQLTLL 9
           T+YQ+T++
Sbjct: 301 TEYQVTVI 308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TQYQLTL 8
           T+Y+LTL
Sbjct: 478 TEYRLTL 484
>NP_001231118
          Length = 1644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1492 FSQYQL 1497
>NP_001231121
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1395 FSQYQL 1400
>NP_055564
          Length = 1472

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1363 FSQYQL 1368
>NP_001231119
          Length = 1533

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1424 FSQYQL 1429
>NP_001231120
          Length = 1463

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1354 FSQYQL 1359
>NP_001231122
          Length = 1347

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1299 FSQYQL 1304
>NP_001003698
          Length = 1687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>NP_001161816
          Length = 1687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>NP_001003699
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>NP_001003700
          Length = 1476

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>NP_703149
          Length = 406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FTQYQL 6
           FTQ+QL
Sbjct: 146 FTQFQL 151
>NP_001191354
          Length = 1640

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FTQYQL 6
           F+QYQL
Sbjct: 683 FSQYQL 688
>XP_006720406
          Length = 1591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1439 FSQYQL 1444
>XP_006720404
          Length = 1477

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1439 FSQYQL 1444
>XP_006720403
          Length = 1486

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1439 FSQYQL 1444
>XP_006720402
          Length = 1487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1439 FSQYQL 1444
>XP_006720401
          Length = 1504

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1395 FSQYQL 1400
>XP_006720400
          Length = 1526

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1439 FSQYQL 1444
>XP_006720399
          Length = 1548

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FTQYQL 6
            F+QYQL
Sbjct: 1439 FSQYQL 1444
>XP_006715224
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_005249329
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_006715223
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_006715222
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_005249333
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_006715221
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_006715220
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_005249332
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
>XP_006715219
          Length = 1742

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  TQYQLTL 8
          TQ+QLT+
Sbjct: 77 TQHQLTM 83
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.144    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 460,593
Number of extensions: 737
Number of successful extensions: 65
Number of sequences better than 10000.0: 64
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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