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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              20     509
XP_005262424                                                           20     509
NP_653226                                                              17    3301
NP_001271457                                                           17    3301
NP_001271456                                                           17    3301
NP_060280                                                              17    3301
NP_001271458                                                           17    3301
XP_005255463                                                           17    3301
XP_006720964                                                           17    3301
XP_005255461                                                           17    3301
XP_005255460                                                           17    3301
XP_005255459                                                           17    3301
XP_006711799                                                           17    3301
NP_060336                                                              16    5631
XP_005250316                                                           16    7355
NP_036304                                                              16    7355
NP_001156971                                                           16    7355
NP_277041                                                              16    7355
NP_071407                                                              15    9605
NP_001178249                                                           15    9605
NP_001265560                                                           15    9605
NP_001178250                                                           15    9605
NP_068712                                                              15    9605
NP_000805                                                              15    9605
XP_006718005                                                           15    9605
XP_006718004                                                           15    9605
XP_006718003                                                           15    9605
XP_005275746                                                           15    9605
XP_003403671                                                           15    9605
XP_006710003                                                           15    9605

>NP_722576
          Length = 3080

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FTKNSAVST 9
           FTKNS VST
Sbjct: 379 FTKNSVVST 387



>XP_005262424
          Length = 2875

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FTKNSAVST 9
           FTKNS VST
Sbjct: 174 FTKNSVVST 182



>NP_653226
          Length = 1081

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTK+SA+S
Sbjct: 810 FTKHSAIS 817



>NP_001271457
          Length = 408

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 381 FTKNSALT 388



>NP_001271456
          Length = 697

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 670 FTKNSALT 677



>NP_060280
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 458 FTKNSALT 465



>NP_001271458
          Length = 408

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 381 FTKNSALT 388



>XP_005255463
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 458 FTKNSALT 465



>XP_006720964
          Length = 485

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 458 FTKNSALT 465



>XP_005255461
          Length = 487

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 460 FTKNSALT 467



>XP_005255460
          Length = 610

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 583 FTKNSALT 590



>XP_005255459
          Length = 624

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTKNSA++
Sbjct: 597 FTKNSALT 604



>XP_006711799
          Length = 1091

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FTK+SA+S
Sbjct: 820 FTKHSAIS 827



>NP_060336
          Length = 260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FTKNSAVS 8
           FT+N+A+S
Sbjct: 126 FTQNNAIS 133



>XP_005250316
          Length = 561

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTKNSAVST 9
           F KN+ VST
Sbjct: 195 FLKNALVST 203



>NP_036304
          Length = 618

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTKNSAVST 9
           F KN+ VST
Sbjct: 195 FLKNALVST 203



>NP_001156971
          Length = 568

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTKNSAVST 9
           F KN+ VST
Sbjct: 145 FLKNALVST 153



>NP_277041
          Length = 580

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTKNSAVST 9
           F KN+ VST
Sbjct: 157 FLKNALVST 165



>NP_071407
          Length = 3354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1420 FTSDSAVS 1427



>NP_001178249
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TKNSAVS 8
           T+NSA+S
Sbjct: 303 TRNSAIS 309



>NP_001265560
          Length = 388

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TKNSAVS 8
           T+NSA+S
Sbjct: 303 TRNSAIS 309



>NP_001178250
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TKNSAVS 8
           T+NSA+S
Sbjct: 317 TRNSAIS 323



>NP_068712
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TKNSAVS 8
           T+NSA+S
Sbjct: 388 TRNSAIS 394



>NP_000805
          Length = 473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   TKNSAVS 8
           T+NSA+S
Sbjct: 388 TRNSAIS 394



>XP_006718005
          Length = 3397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1463 FTSDSAVS 1470



>XP_006718004
          Length = 3399

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1465 FTSDSAVS 1472



>XP_006718003
          Length = 3419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1485 FTSDSAVS 1492



>XP_005275746
          Length = 3352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1418 FTSDSAVS 1425



>XP_003403671
          Length = 3354

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1420 FTSDSAVS 1427



>XP_006710003
          Length = 3374

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FTKNSAVS 8
            FT +SAVS
Sbjct: 1440 FTSDSAVS 1447



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.301    0.104    0.252 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 333,050
Number of extensions: 288
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)