Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_000757                                                              17    2528
NP_689846                                                              17    4312
NP_001018123                                                           17    4312
NP_612152                                                              17    4312
XP_006715715                                                           17    4312
NP_000753                                                              16    5631
NP_542194                                                              16    5631
NP_001275637                                                           16    5631
NP_085079                                                              16    5631
NP_000755                                                              16    5631
NP_954650                                                              16    5631
NP_001135389                                                           16    5631
NP_001229510                                                           16    7355
NP_002909                                                              16    7355
NP_001171864                                                           16    7355
NP_053586                                                              16    7355
NP_053584                                                              16    7355
NP_004874                                                              16    7355
NP_053585                                                              16    7355
NP_940873                                                              16    7355
XP_006723636                                                           16    7355
XP_006722894                                                           16    7355
XP_006722893                                                           16    7355
XP_006722892                                                           16    7355
XP_006722781                                                           16    7355
XP_005272524                                                           16    7355
XP_006714873                                                           16    7355
XP_006714872                                                           16    7355
XP_006714871                                                           16    7355
NP_001136245                                                           15    9605
NP_001136239                                                           15    9605
NP_001136236                                                           15    9605
NP_001136244                                                           15    9605
NP_001136238                                                           15    9605
NP_001136240                                                           15    9605
NP_001136243                                                           15    9605
NP_001136242                                                           15    9605
NP_001136235                                                           15    9605
NP_001136237                                                           15    9605
NP_001136241                                                           15    9605
NP_149045                                                              15    9605
NP_997191                                                              15    9605
NP_001138890                                                           15    9605
NP_075462                                                              15    9605
NP_001152956                                                           15    9605
NP_001166281                                                           15    9605
NP_150232                                                              15    9605
NP_079540                                                              15    9605
XP_005275685                                                           15    9605
XP_005275547                                                           15    9605
XP_005275376                                                           15    9605
XP_005275252                                                           15    9605
XP_005275120                                                           15    9605
XP_005272964                                                           15    9605
XP_005274955                                                           15    9605
XP_006724234                                                           15    9605
XP_005261462                                                           15    9605
XP_005257635                                                           15    9605
XP_006718013                                                           15    9605
XP_005249528                                                           15    9605
XP_006712169                                                           15    9605
XP_005264634                                                           15    9605
XP_006711682                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FTASQTGQV 9
            FTASQTG V
Sbjct: 1922 FTASQTGLV 1930
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    FTASQTGQV 9
            FTASQTG V
Sbjct: 1717 FTASQTGLV 1725
>NP_000757
          Length = 494

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTA+ TGQ+
Sbjct: 211 FTATSTGQL 219
>NP_689846
          Length = 859

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           F +SQTG+V
Sbjct: 152 FISSQTGKV 160
>NP_001018123
          Length = 859

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           F +SQTG+V
Sbjct: 152 FISSQTGKV 160
>NP_612152
          Length = 2849

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FTASQTG 7
           FTASQ+G
Sbjct: 260 FTASQSG 266
>XP_006715715
          Length = 2023

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FTASQTG 7
           FTASQ+G
Sbjct: 260 FTASQSG 266
>NP_000753
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FT++ TGQ+
Sbjct: 211 FTSTSTGQL 219
>NP_542194
          Length = 1661

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   ASQTGQV 9
           A+QTGQV
Sbjct: 285 AAQTGQV 291
>NP_001275637
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  TASQTGQV 9
          +ASQTG++
Sbjct: 5  SASQTGEI 12
>NP_085079
          Length = 443

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FT++ TGQ+
Sbjct: 160 FTSTSTGQL 168
>NP_000755
          Length = 494

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FT++ TGQ+
Sbjct: 211 FTSTSTGQL 219
>NP_954650
          Length = 1016

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  ASQTGQV 9
          A+QTGQV
Sbjct: 47 AAQTGQV 53
>NP_001135389
          Length = 1335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   TASQTGQ 8
           TASQTG+
Sbjct: 566 TASQTGK 572
>NP_001229510
          Length = 944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  FTASQT 6
          FTASQT
Sbjct: 31 FTASQT 36
>NP_002909
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TASQTG 7
           TASQTG
Sbjct: 124 TASQTG 129
>NP_001171864
          Length = 784

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>NP_053586
          Length = 852

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>NP_053584
          Length = 844

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>NP_004874
          Length = 850

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>NP_053585
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>NP_940873
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ASQTGQ 8
           ASQTGQ
Sbjct: 692 ASQTGQ 697
>XP_006723636
          Length = 944

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  FTASQT 6
          FTASQT
Sbjct: 31 FTASQT 36
>XP_006722894
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TASQTG 7
          TASQTG
Sbjct: 15 TASQTG 20
>XP_006722893
          Length = 870

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  TASQTG 7
          TASQTG
Sbjct: 15 TASQTG 20
>XP_006722892
          Length = 979

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   TASQTG 7
           TASQTG
Sbjct: 124 TASQTG 129
>XP_006722781
          Length = 821

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ASQTGQ 8
           ASQTGQ
Sbjct: 692 ASQTGQ 697
>XP_005272524
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   ASQTGQ 8
           ASQTGQ
Sbjct: 743 ASQTGQ 748
>XP_006714873
          Length = 422

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>XP_006714872
          Length = 629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SQTGQV 9
           SQTGQV
Sbjct: 244 SQTGQV 249
>XP_006714871
          Length = 647

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4  SQTGQV 9
          SQTGQV
Sbjct: 41 SQTGQV 46
>NP_001136245
          Length = 1932

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 430 FTVTQTG 436
>NP_001136239
          Length = 1915

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 415 FTVTQTG 421
>NP_001136236
          Length = 1957

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136244
          Length = 1677

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136238
          Length = 1952

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136240
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 430 FTVTQTG 436
>NP_001136243
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 457 FTVTQTG 463
>NP_001136242
          Length = 1539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136235
          Length = 1962

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 457 FTVTQTG 463
>NP_001136237
          Length = 1886

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_001136241
          Length = 1790

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 464 FTVTQTG 470
>NP_149045
          Length = 1955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>NP_997191
          Length = 1888

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TASQTGQ 8
           TASQ GQ
Sbjct: 322 TASQLGQ 328
>NP_001138890
          Length = 2481

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TASQTGQ 8
            TAS+TG+
Sbjct: 1840 TASETGE 1846
>NP_075462
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTASQTGQV 9
           F+AS  GQV
Sbjct: 281 FSASTDGQV 289
>NP_001152956
          Length = 1736

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TASQTGQ 8
           TASQ GQ
Sbjct: 322 TASQLGQ 328
>NP_001166281
          Length = 593

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTASQTGQV 9
           F+AS  GQV
Sbjct: 281 FSASTDGQV 289
>NP_150232
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>NP_079540
          Length = 503

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FTASQTGQV 9
           FTA + G+V
Sbjct: 221 FTAQEVGKV 229
>XP_005275685
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_005275547
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_005275376
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_005275252
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_005275120
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_005272964
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_005274955
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_006724234
          Length = 2363

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TASQTGQ 8
            TAS+TG+
Sbjct: 1722 TASETGE 1728
>XP_005261462
          Length = 2473

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    TASQTGQ 8
            TAS+TG+
Sbjct: 1840 TASETGE 1846
>XP_005257635
          Length = 605

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FTASQTGQV 9
           F+AS  GQV
Sbjct: 281 FSASTDGQV 289
>XP_006718013
          Length = 1778

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FTASQTG 7
           FT +QTG
Sbjct: 452 FTVTQTG 458
>XP_005249528
          Length = 465

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FTASQTGQV 9
           FTAS +G+V
Sbjct: 440 FTASFSGKV 448
>XP_006712169
          Length = 344

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FTASQTGQV 9
           FTA + G+V
Sbjct: 221 FTAQEVGKV 229
>XP_005264634
          Length = 410

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FTASQTGQV 9
           FTA + G+V
Sbjct: 128 FTAQEVGKV 136
>XP_006711682
          Length = 1739

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   TASQTGQ 8
           TASQ GQ
Sbjct: 173 TASQLGQ 179
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.116    0.302 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 432,999
Number of extensions: 631
Number of successful extensions: 65
Number of sequences better than 10000.0: 65
Number of HSP's gapped: 65
Number of HSP's successfully gapped: 65
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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