Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              18    1482
XP_005262424                                                           18    1482
NP_071940                                                              17    4312
XP_005268066                                                           17    4312
NP_001182726                                                           16    5631
NP_056179                                                              16    5631
NP_009107                                                              16    7355
NP_001273081                                                           16    7355
NP_938016                                                              16    7355
NP_001161142                                                           16    7355
XP_005260691                                                           16    7355
XP_006723597                                                           16    7355
XP_005260690                                                           16    7355
XP_006718838                                                           16    7355
NP_001265713                                                           15    9605
NP_005818                                                              15    9605
NP_001615                                                              15    9605
NP_909119                                                              15    9605
NP_057537                                                              15    9605
XP_005256986                                                           15    9605
XP_006721695                                                           15    9605
XP_005266896                                                           15    9605
XP_005265280                                                           15    9605
XP_006713268                                                           15    9605
XP_005245101                                                           15    9605
>NP_722576
          Length = 3080

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    FSTLLSSV 8
            FSTLLSSV
Sbjct: 1588 FSTLLSSV 1595
>XP_005262424
          Length = 2875

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    FSTLLSSV 8
            FSTLLSSV
Sbjct: 1383 FSTLLSSV 1390
>NP_071940
          Length = 938

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   FSTLLSS 7
           FSTLLSS
Sbjct: 348 FSTLLSS 354
>XP_005268066
          Length = 1172

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1   FSTLLSS 7
           FSTLLSS
Sbjct: 582 FSTLLSS 588
>NP_001182726
          Length = 130

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FSTLLSSV 8
          FSTL SS+
Sbjct: 7  FSTLFSSI 14
>NP_056179
          Length = 160

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FSTLLSSV 8
          FSTL SS+
Sbjct: 7  FSTLFSSI 14
>NP_009107
          Length = 140

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3  TLLSSVI 9
          TLLSSVI
Sbjct: 57 TLLSSVI 63
>NP_001273081
          Length = 223

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           F T+LSSV
Sbjct: 140 FGTMLSSV 147
>NP_938016
          Length = 235

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           F T+LSSV
Sbjct: 152 FGTMLSSV 159
>NP_001161142
          Length = 152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           FSTLLS V
Sbjct: 128 FSTLLSLV 135
>XP_005260691
          Length = 152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           FSTLLS V
Sbjct: 128 FSTLLSLV 135
>XP_006723597
          Length = 152

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           FSTLLS V
Sbjct: 128 FSTLLSLV 135
>XP_005260690
          Length = 195

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           FSTLLS V
Sbjct: 171 FSTLLSLV 178
>XP_006718838
          Length = 217

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FSTLLSSV 8
           F T+LSSV
Sbjct: 134 FGTMLSSV 141
>NP_001265713
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSTLLSSVI 9
           F T+L+SVI
Sbjct: 211 FFTILASVI 219
>NP_005818
          Length = 359

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSTLLSSVI 9
           F T+L+SVI
Sbjct: 315 FFTILASVI 323
>NP_001615
          Length = 1723

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   FSTLLSSV 8
           FS+LLSS+
Sbjct: 835 FSSLLSSL 842
>NP_909119
          Length = 715

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   STLLSSVI 9
           STL+SSV+
Sbjct: 469 STLVSSVL 476
>NP_057537
          Length = 722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   STLLSSVI 9
           STL+SSV+
Sbjct: 476 STLVSSVL 483
>XP_005256986
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSTLLSSVI 9
           F T+L+SVI
Sbjct: 211 FFTILASVI 219
>XP_006721695
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSTLLSSVI 9
           F T+L+SVI
Sbjct: 349 FFTILASVI 357
>XP_005266896
          Length = 2131

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    FSTLLSSV 8
            FS+LLSS+
Sbjct: 1243 FSSLLSSL 1250
>XP_005265280
          Length = 644

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   STLLSSVI 9
           STL+SSV+
Sbjct: 398 STLVSSVL 405
>XP_006713268
          Length = 695

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   STLLSSVI 9
           STL+SSV+
Sbjct: 476 STLVSSVL 483
>XP_005245101
          Length = 469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FSTLLSSV 8
          FST +SSV
Sbjct: 43 FSTFVSSV 50
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.327    0.133    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 299,150
Number of extensions: 393
Number of successful extensions: 25
Number of sequences better than 10000.0: 25
Number of HSP's gapped: 25
Number of HSP's successfully gapped: 25
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.1 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package