Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001257436                                                           21     175
NP_001257437                                                           21     175
NP_006281                                                              21     175
XP_005267176                                                           21     175
NP_694984                                                              17    2528
XP_006726560                                                           17    2528
XP_006724701                                                           17    2528
XP_005262172                                                           17    2528
XP_005262170                                                           17    2528
NP_065861                                                              17    3301
XP_005267973                                                           17    3301
NP_078966                                                              16    5631
NP_055383                                                              16    5631
NP_056227                                                              16    5631
NP_060493                                                              16    5631
XP_006713751                                                           16    5631
XP_005247655                                                           16    5631
XP_005247654                                                           16    5631
XP_005247335                                                           16    5631
XP_005247333                                                           16    5631
XP_005247330                                                           16    5631
NP_004509                                                              16    7355
NP_742106                                                              16    7355
NP_742105                                                              16    7355
NP_742104                                                              16    7355
NP_742107                                                              16    7355
XP_006723855                                                           16    7355
XP_006723854                                                           16    7355
XP_006723853                                                           16    7355
XP_006723852                                                           16    7355
XP_006723851                                                           16    7355
XP_006723850                                                           16    7355
NP_065866                                                              15    9605
NP_116586                                                              15    9605
NP_878918                                                              15    9605
NP_055995                                                              15    9605
NP_573400                                                              15    9605
NP_008981                                                              15    9605
NP_689914                                                              15    9605
NP_001245298                                                           15    9605
NP_001245297                                                           15    9605
NP_001035982                                                           15    9605
NP_001245295                                                           15    9605
NP_001245296                                                           15    9605
NP_001245299                                                           15    9605
XP_006723752                                                           15    9605
XP_006723751                                                           15    9605
XP_006723750                                                           15    9605
XP_006723749                                                           15    9605
XP_006723748                                                           15    9605
XP_005267517                                                           15    9605
XP_005267516                                                           15    9605
XP_005267515                                                           15    9605
XP_005267514                                                           15    9605
XP_005267513                                                           15    9605
XP_005267512                                                           15    9605
XP_005267511                                                           15    9605
XP_006719939                                                           15    9605
NP_112194                                                              15    9605
>NP_001257436
          Length = 790

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSTIKETDT 9
           FST+KETDT
Sbjct: 127 FSTLKETDT 135
>NP_001257437
          Length = 790

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSTIKETDT 9
           FST+KETDT
Sbjct: 127 FSTLKETDT 135
>NP_006281
          Length = 790

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSTIKETDT 9
           FST+KETDT
Sbjct: 127 FSTLKETDT 135
>XP_005267176
          Length = 790

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSTIKETDT 9
           FST+KETDT
Sbjct: 127 FSTLKETDT 135
>NP_694984
          Length = 1802

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    FSTIKET 7
            FST+KET
Sbjct: 1372 FSTVKET 1378
>XP_006726560
          Length = 197

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  TIKETDT 9
          T+KETDT
Sbjct: 32 TLKETDT 38
>XP_006724701
          Length = 1398

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           FST+KET
Sbjct: 968 FSTVKET 974
>XP_005262172
          Length = 1631

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    FSTIKET 7
            FST+KET
Sbjct: 1201 FSTVKET 1207
>XP_005262170
          Length = 1752

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    FSTIKET 7
            FST+KET
Sbjct: 1322 FSTVKET 1328
>NP_065861
          Length = 509

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FSTIKETDT 9
          FST+ ET+T
Sbjct: 57 FSTMPETET 65
>XP_005267973
          Length = 537

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FSTIKETDT 9
          FST+ ET+T
Sbjct: 85 FSTMPETET 93
>NP_078966
          Length = 14507

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FSTIKETDT 9
            FST+  TDT
Sbjct: 2475 FSTMVSTDT 2483
>NP_055383
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   IKETDT 9
           IKETDT
Sbjct: 659 IKETDT 664
>NP_056227
          Length = 567

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TIKETD 8
           TIKETD
Sbjct: 551 TIKETD 556
>NP_060493
          Length = 1422

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TIKETD 8
          TIKETD
Sbjct: 7  TIKETD 12
>XP_006713751
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TIKETD 8
          TIKETD
Sbjct: 7  TIKETD 12
>XP_005247655
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TIKETD 8
          TIKETD
Sbjct: 7  TIKETD 12
>XP_005247654
          Length = 1423

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  TIKETD 8
          TIKETD
Sbjct: 7  TIKETD 12
>XP_005247335
          Length = 400

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TIKETD 8
           TIKETD
Sbjct: 384 TIKETD 389
>XP_005247333
          Length = 431

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TIKETD 8
           TIKETD
Sbjct: 415 TIKETD 420
>XP_005247330
          Length = 497

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3   TIKETD 8
           TIKETD
Sbjct: 481 TIKETD 486
>NP_004509
          Length = 844

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>NP_742106
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>NP_742105
          Length = 872

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>NP_742104
          Length = 854

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>NP_742107
          Length = 393

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>XP_006723855
          Length = 856

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>XP_006723854
          Length = 858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>XP_006723853
          Length = 868

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>XP_006723852
          Length = 876

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>XP_006723851
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>XP_006723850
          Length = 886

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FSTIKE
Sbjct: 112 FSTIKE 117
>NP_065866
          Length = 896

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FST+KE
Sbjct: 360 FSTVKE 365
>NP_116586
          Length = 1040

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FSTIKE 6
           FST+KE
Sbjct: 360 FSTVKE 365
>NP_878918
          Length = 6907

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>NP_055995
          Length = 6885

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>NP_573400
          Length = 1460

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TIKETDT 9
           T+KE DT
Sbjct: 94  TLKENDT 100
>NP_008981
          Length = 1441

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   TIKETDT 9
           T+KE DT
Sbjct: 94  TLKENDT 100
>NP_689914
          Length = 5058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FSTIKET 7
            FS++KET
Sbjct: 2329 FSSLKET 2335
>NP_001245298
          Length = 1112

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 425 WSTVKET 431
>NP_001245297
          Length = 1123

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 355 WSTVKET 361
>NP_001035982
          Length = 1193

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 425 WSTVKET 431
>NP_001245295
          Length = 1182

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 414 WSTVKET 420
>NP_001245296
          Length = 1147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 379 WSTVKET 385
>NP_001245299
          Length = 691

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 162 WSTVKET 168
>XP_006723752
          Length = 1387

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TIKETDT 9
          T+KE DT
Sbjct: 31 TLKENDT 37
>XP_006723751
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TIKETDT 9
          T+KE DT
Sbjct: 20 TLKENDT 26
>XP_006723750
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TIKETDT 9
          T+KE DT
Sbjct: 20 TLKENDT 26
>XP_006723749
          Length = 1428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TIKETDT 9
          T+KE DT
Sbjct: 31 TLKENDT 37
>XP_006723748
          Length = 1437

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3  TIKETDT 9
          T+KE DT
Sbjct: 31 TLKENDT 37
>XP_005267517
          Length = 6883

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 4979 LKETDT 4984
>XP_005267516
          Length = 6884

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267515
          Length = 6899

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267514
          Length = 6908

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267513
          Length = 6921

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267512
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_005267511
          Length = 6922

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    IKETDT 9
            +KETDT
Sbjct: 5018 LKETDT 5023
>XP_006719939
          Length = 930

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 162 WSTVKET 168
>NP_112194
          Length = 849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FSTIKET 7
           +ST+KET
Sbjct: 162 WSTVKET 168
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.305    0.119    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 494,286
Number of extensions: 914
Number of successful extensions: 59
Number of sequences better than 10000.0: 59
Number of HSP's gapped: 59
Number of HSP's successfully gapped: 59
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package