Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_733751                                                              18    1935
XP_006716142                                                           18    1935
XP_005250088                                                           18    1935
XP_006716141                                                           18    1935
XP_005250085                                                           18    1935
XP_006716140                                                           18    1935
XP_005250084                                                           18    1935
XP_005250083                                                           18    1935
XP_005250082                                                           18    1935
NP_001155059                                                           16    5631
NP_002094                                                              16    5631
NP_054808                                                              16    5631
NP_001008564                                                           16    5631
NP_671726                                                              16    5631
NP_689842                                                              16    5631
NP_001034806                                                           16    5631
NP_001035878                                                           16    5631
XP_005266657                                                           16    5631
XP_005251445                                                           16    5631
XP_005251444                                                           16    5631
XP_005251443                                                           16    5631
XP_005263298                                                           16    5631
XP_006714387                                                           16    5631
XP_006714386                                                           16    5631
XP_005263300                                                           16    5631
XP_006714385                                                           16    5631
XP_005263299                                                           16    5631
XP_006714384                                                           16    5631
XP_005263295                                                           16    5631
XP_006714383                                                           16    5631
XP_006714382                                                           16    5631
XP_006714381                                                           16    5631
XP_005270562                                                           16    5631
NP_620311                                                              15    9605
NP_001185748                                                           15    9605
NP_079510                                                              15    9605
NP_620310                                                              15    9605
NP_001185749                                                           15    9605
NP_055391                                                              15    9605
NP_001185747                                                           15    9605
NP_001073312                                                           15    9605
NP_055665                                                              15    9605
NP_001028289                                                           15    9605
XP_005254755                                                           15    9605
XP_006717872                                                           15    9605
XP_005269777                                                           15    9605
XP_005269776                                                           15    9605
XP_006717871                                                           15    9605
XP_005269775                                                           15    9605
XP_006713496                                                           15    9605
XP_006710775                                                           15    9605
XP_005263536                                                           15    9605
>NP_733751
          Length = 4911

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 770 FSSSADISK 778
>XP_006716142
          Length = 4927

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>XP_005250088
          Length = 4928

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>XP_006716141
          Length = 4959

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>XP_005250085
          Length = 4979

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>XP_006716140
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>XP_005250084
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>XP_005250083
          Length = 4982

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 770 FSSSADISK 778
>XP_005250082
          Length = 4983

 Score = 17.7 bits (34), Expect =  1935
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           FSSSAD SK
Sbjct: 771 FSSSADISK 779
>NP_001155059
          Length = 673

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           F+SSAD+ K
Sbjct: 402 FNSSADRVK 410
>NP_002094
          Length = 737

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           F+SSAD+ K
Sbjct: 466 FNSSADRVK 474
>NP_054808
          Length = 599

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           FSSS+DK
Sbjct: 221 FSSSSDK 227
>NP_001008564
          Length = 587

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           FSSS+DK
Sbjct: 209 FSSSSDK 215
>NP_671726
          Length = 620

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 303 FSNSSDRAK 311
>NP_689842
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 453 FSNSSDRAK 461
>NP_001034806
          Length = 414

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 247 FTSSADK 253
>NP_001035878
          Length = 930

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 608 FSNSSDRAK 616
>XP_005266657
          Length = 566

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           FSSS+DK
Sbjct: 221 FSSSSDK 227
>XP_005251445
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 386 FSNSSDRAK 394
>XP_005251444
          Length = 708

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 386 FSNSSDRAK 394
>XP_005251443
          Length = 775

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 453 FSNSSDRAK 461
>XP_005263298
          Length = 448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 281 FTSSADK 287
>XP_006714387
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 112 FTSSADK 118
>XP_006714386
          Length = 295

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 112 FTSSADK 118
>XP_005263300
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 154 FTSSADK 160
>XP_006714385
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 154 FTSSADK 160
>XP_005263299
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 154 FTSSADK 160
>XP_006714384
          Length = 463

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_005263295
          Length = 464

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 281 FTSSADK 287
>XP_006714383
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_006714382
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_006714381
          Length = 479

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FSSSADK 7
           F+SSADK
Sbjct: 296 FTSSADK 302
>XP_005270562
          Length = 795

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   FSSSADKSK 9
           FS+S+D++K
Sbjct: 478 FSNSSDRAK 486
>NP_620311
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 177 YPSAADKTK 185
>NP_001185748
          Length = 602

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 177 YPSAADKTK 185
>NP_079510
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSSADKS 8
           SSS+DKS
Sbjct: 249 SSSSDKS 255
>NP_620310
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>NP_001185749
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 177 YPSAADKTK 185
>NP_055391
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>NP_001185747
          Length = 586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>NP_001073312
          Length = 1759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    FSSSAD 6
            FSSSAD
Sbjct: 1551 FSSSAD 1556
>NP_055665
          Length = 1099

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSSADKS 8
            +SSADKS
Sbjct: 1090 NSSADKS 1096
>NP_001028289
          Length = 1075

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    SSSADKS 8
            +SSADKS
Sbjct: 1066 NSSADKS 1072
>XP_005254755
          Length = 305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSSADKS 8
           SSS+DKS
Sbjct: 249 SSSSDKS 255
>XP_006717872
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 177 YPSAADKTK 185
>XP_005269777
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>XP_005269776
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>XP_006717871
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>XP_005269775
          Length = 594

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSSSADKSK 9
           + S+ADK+K
Sbjct: 169 YPSAADKTK 177
>XP_006713496
          Length = 591

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SSSADKS 8
           +SSADKS
Sbjct: 582 NSSADKS 588
>XP_006710775
          Length = 1759

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    FSSSAD 6
            FSSSAD
Sbjct: 1551 FSSSAD 1556
>XP_005263536
          Length = 1783

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1    FSSSAD 6
            FSSSAD
Sbjct: 1575 FSSSAD 1580
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.287   0.0978    0.221 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 473,389
Number of extensions: 748
Number of successful extensions: 52
Number of sequences better than 10000.0: 52
Number of HSP's gapped: 52
Number of HSP's successfully gapped: 52
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (14.9 bits)
S2: 28 (15.4 bits)

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