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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_919299                                                              17    3301
XP_006719831                                                           17    3301
NP_060371                                                              16    5631
XP_005253963                                                           16    5631
XP_005253962                                                           16    5631
NP_001137291                                                           16    5631
NP_006501                                                              16    7355
NP_001191746                                                           16    7355
NP_116217                                                              16    7355
NP_002800                                                              16    7355
NP_001121904                                                           16    7355
NP_689688                                                              16    7355
NP_055803                                                              16    7355
NP_001276051                                                           16    7355
NP_001106189                                                           16    7355
NP_001106188                                                           16    7355
NP_008970                                                              16    7355
NP_001264154                                                           16    7355
NP_066024                                                              16    7355
XP_006723092                                                           16    7355
XP_006720074                                                           16    7355
XP_005267344                                                           16    7355
XP_006714061                                                           16    7355
XP_005248132                                                           16    7355
XP_005248131                                                           16    7355
XP_005248130                                                           16    7355
XP_005248129                                                           16    7355
XP_006714060                                                           16    7355
XP_005248128                                                           16    7355
XP_005248127                                                           16    7355
XP_005248126                                                           16    7355
XP_005248125                                                           16    7355
XP_005248120                                                           16    7355
XP_006714059                                                           16    7355
XP_005248119                                                           16    7355
XP_005248118                                                           16    7355
XP_005248117                                                           16    7355
XP_005248116                                                           16    7355
XP_005248115                                                           16    7355
XP_005248114                                                           16    7355
NP_003741                                                              15    9605
NP_001278340                                                           15    9605
NP_620305                                                              15    9605
NP_115571                                                              15    9605
NP_001186408                                                           15    9605
NP_078988                                                              15    9605
NP_001186409                                                           15    9605
XP_006724107                                                           15    9605
XP_006724106                                                           15    9605
XP_005272299                                                           15    9605
XP_006715247                                                           15    9605
XP_006715246                                                           15    9605
XP_006715245                                                           15    9605
XP_006713783                                                           15    9605
XP_005247745                                                           15    9605
XP_006713782                                                           15    9605
NP_006290                                                              15    9605
NP_006497                                                              15    9605

>NP_919299
          Length = 498

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSLSYSRKS 9
           FS++YSR S
Sbjct: 117 FSVTYSRNS 125



>XP_006719831
          Length = 479

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSLSYSRKS 9
           FS++YSR S
Sbjct: 98  FSVTYSRNS 106



>NP_060371
          Length = 816

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSLSYSRKS 9
           F ++YSRK+
Sbjct: 692 FRMNYSRKN 700



>XP_005253963
          Length = 748

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSLSYSRKS 9
           F ++YSRK+
Sbjct: 624 FRMNYSRKN 632



>XP_005253962
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSLSYSRKS 9
           F ++YSRK+
Sbjct: 746 FRMNYSRKN 754



>NP_001137291
          Length = 888

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSLSYSRKS 9
           F ++YSRK+
Sbjct: 764 FRMNYSRKN 772



>NP_006501
          Length = 513

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSLSYS 6
           FSLSYS
Sbjct: 474 FSLSYS 479



>NP_001191746
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SYSRKS 9
           SYSRKS
Sbjct: 275 SYSRKS 280



>NP_116217
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SYSRKS 9
           SYSRKS
Sbjct: 276 SYSRKS 281



>NP_002800
          Length = 534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           SLSYSR S
Sbjct: 411 SLSYSRIS 418



>NP_001121904
          Length = 162

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  FSLSYSR 7
          FSLS+SR
Sbjct: 76 FSLSWSR 82



>NP_689688
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SYSRKS 9
           SYSRKS
Sbjct: 276 SYSRKS 281



>NP_055803
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>NP_001276051
          Length = 1069

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>NP_001106189
          Length = 1056

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>NP_001106188
          Length = 1057

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>NP_008970
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSLSYS 6
           FSLSYS
Sbjct: 512 FSLSYS 517



>NP_001264154
          Length = 470

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  FSLSYSR 7
          FSLS+SR
Sbjct: 77 FSLSWSR 83



>NP_066024
          Length = 469

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  FSLSYSR 7
          FSLS+SR
Sbjct: 76 FSLSWSR 82



>XP_006723092
          Length = 574

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 4   SYSRKS 9
           SYSRKS
Sbjct: 275 SYSRKS 280



>XP_006720074
          Length = 1051

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSLSYS 6
           FSLSYS
Sbjct: 389 FSLSYS 394



>XP_005267344
          Length = 1174

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1   FSLSYS 6
           FSLSYS
Sbjct: 512 FSLSYS 517



>XP_006714061
          Length = 766

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248132
          Length = 1044

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248131
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248130
          Length = 1074

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248129
          Length = 1082

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_006714060
          Length = 1085

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248128
          Length = 1086

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248127
          Length = 1322

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248126
          Length = 1359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248125
          Length = 1439

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248120
          Length = 1549

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_006714059
          Length = 1600

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248119
          Length = 1601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248118
          Length = 1602

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248117
          Length = 1626

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248116
          Length = 1627

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248115
          Length = 1629

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>XP_005248114
          Length = 1630

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   SLSYSRK 8
           SL YSRK
Sbjct: 116 SLDYSRK 122



>NP_003741
          Length = 1382

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FSLSYSRKS 9
           F L Y+RK+
Sbjct: 184 FCLQYTRKA 192



>NP_001278340
          Length = 2108

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    FSLSYSRKS 9
            FS+S SR+S
Sbjct: 1949 FSISPSRRS 1957



>NP_620305
          Length = 2426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    FSLSYSRKS 9
            FS+S SR+S
Sbjct: 1949 FSISPSRRS 1957



>NP_115571
          Length = 2303

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    FSLSYSRKS 9
            FS+S SR+S
Sbjct: 1949 FSISPSRRS 1957



>NP_001186408
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SYSR+S
Sbjct: 395 SKSYSRRS 402



>NP_078988
          Length = 773

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FSLSYSR 7
           FS+SY R
Sbjct: 681 FSISYDR 687



>NP_001186409
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SYSR+S
Sbjct: 344 SKSYSRRS 351



>XP_006724107
          Length = 2298

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    FSLSYSRKS 9
            FS+S SR+S
Sbjct: 1949 FSISPSRRS 1957



>XP_006724106
          Length = 2459

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    FSLSYSRKS 9
            FS+S SR+S
Sbjct: 1949 FSISPSRRS 1957



>XP_005272299
          Length = 599

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 159 SLSYSR 164




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 187 SLSYSR 192




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 243 SLSYSR 248




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 336 SLSYSR 341




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 392 SLSYSR 397




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 448 SLSYSR 453




 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   SLSYSR 7
           SLSYSR
Sbjct: 466 SLSYSR 471



>XP_006715247
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SYSR+S
Sbjct: 395 SKSYSRRS 402



>XP_006715246
          Length = 445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SYSR+S
Sbjct: 395 SKSYSRRS 402



>XP_006715245
          Length = 496

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SYSR+S
Sbjct: 446 SKSYSRRS 453



>XP_006713783
          Length = 633

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  SLSYSRKS 9
          S SY+RKS
Sbjct: 11 SSSYTRKS 18



>XP_005247745
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SY+RKS
Sbjct: 232 SSSYTRKS 239



>XP_006713782
          Length = 854

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SY+RKS
Sbjct: 232 SSSYTRKS 239



>NP_006290
          Length = 394

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SYSR+S
Sbjct: 344 SKSYSRRS 351



>NP_006497
          Length = 849

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   SLSYSRKS 9
           S SY+RKS
Sbjct: 232 SSSYTRKS 239



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.118    0.296 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 502,218
Number of extensions: 782
Number of successful extensions: 64
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 64
Number of HSP's successfully gapped: 64
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)