Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_006197                                                              20     509
XP_006714104                                                           20     509
XP_005265800                                                           20     509
XP_006714103                                                           20     509
XP_006714102                                                           20     509
NP_689778                                                              18    1482
NP_009148                                                              18    1935
NP_665858                                                              18    1935
NP_665859                                                              18    1935
XP_005247145                                                           18    1935
XP_005247144                                                           18    1935
XP_005247143                                                           18    1935
XP_006713548                                                           18    1935
NP_005436                                                              17    4312
NP_001229766                                                           17    4312
NP_036437                                                              17    4312
NP_004682                                                              17    4312
NP_001073888                                                           17    4312
XP_006722211                                                           17    4312
XP_006722210                                                           17    4312
XP_006722209                                                           17    4312
XP_006722208                                                           17    4312
XP_006722207                                                           17    4312
XP_006718223                                                           17    4312
XP_006718222                                                           17    4312
NP_570603                                                              17    4312
NP_055018                                                              17    4312
NP_001008212                                                           16    5631
NP_068815                                                              16    5631
NP_001008214                                                           16    5631
NP_001008213                                                           16    5631
XP_005257093                                                           16    5631
XP_005257092                                                           16    5631
XP_005257091                                                           16    5631
XP_005257090                                                           16    5631
XP_005252395                                                           16    5631
XP_005252394                                                           16    5631
XP_005252393                                                           16    5631
NP_859058                                                              16    5631
NP_001273545                                                           16    7355
NP_849148                                                              16    7355
NP_001273544                                                           16    7355
NP_055136                                                              16    7355
NP_055651                                                              16    7355
NP_001153508                                                           16    7355
NP_001229288                                                           16    7355
XP_006718152                                                           16    7355
XP_006718151                                                           16    7355
XP_006718150                                                           16    7355
XP_006718149                                                           16    7355
XP_006718148                                                           16    7355
XP_006718147                                                           16    7355
XP_006716378                                                           16    7355
NP_001153509                                                           16    7355
NP_055993                                                              16    7355
NP_004490                                                              16    7355
NP_112556                                                              16    7355
NP_055835                                                              15    9605
NP_001275932                                                           15    9605
NP_001099038                                                           15    9605
NP_001099037                                                           15    9605
NP_001099036                                                           15    9605
NP_071396                                                              15    9605
XP_006715230                                                           15    9605
XP_006715229                                                           15    9605
XP_005249350                                                           15    9605
XP_005249349                                                           15    9605
XP_005249348                                                           15    9605
XP_005249347                                                           15    9605
XP_005249346                                                           15    9605
NP_778227                                                              15    9605
>NP_006197
          Length = 1089

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEAVNL
Sbjct: 321 FSQLEAVNL 329
>XP_006714104
          Length = 832

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEAVNL
Sbjct: 346 FSQLEAVNL 354
>XP_005265800
          Length = 1089

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEAVNL
Sbjct: 321 FSQLEAVNL 329
>XP_006714103
          Length = 1111

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEAVNL
Sbjct: 343 FSQLEAVNL 351
>XP_006714102
          Length = 1114

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEAVNL
Sbjct: 346 FSQLEAVNL 354
>NP_689778
          Length = 350

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           F+E+EAVN+
Sbjct: 135 FTEMEAVNI 143
>NP_009148
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>NP_665858
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>NP_665859
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>XP_005247145
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>XP_005247144
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>XP_005247143
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>XP_006713548
          Length = 212

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  FSELEAVNL 9
          F+ELE VNL
Sbjct: 30 FNELERVNL 38
>NP_005436
          Length = 1217

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   SELEAVN 8
           SELEA+N
Sbjct: 864 SELEAIN 870
>NP_001229766
          Length = 940

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          F  +EAVNL
Sbjct: 74 FGHMEAVNL 82
>NP_036437
          Length = 939

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          F  +EAVNL
Sbjct: 74 FGHMEAVNL 82
>NP_004682
          Length = 351

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSELEAVNL 9
           F ++EAVN+
Sbjct: 135 FEQMEAVNI 143
>NP_001073888
          Length = 810

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEA++L
Sbjct: 732 FSDLEALSL 740
>XP_006722211
          Length = 642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEA++L
Sbjct: 564 FSDLEALSL 572
>XP_006722210
          Length = 642

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEA++L
Sbjct: 564 FSDLEALSL 572
>XP_006722209
          Length = 826

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEA++L
Sbjct: 748 FSDLEALSL 756
>XP_006722208
          Length = 827

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEA++L
Sbjct: 749 FSDLEALSL 757
>XP_006722207
          Length = 839

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   FSELEAVNL 9
           FS+LEA++L
Sbjct: 761 FSDLEALSL 769
>XP_006718223
          Length = 941

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          F  +EAVNL
Sbjct: 76 FGHMEAVNL 84
>XP_006718222
          Length = 942

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          F  +EAVNL
Sbjct: 76 FGHMEAVNL 84
>NP_570603
          Length = 955

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          F  +EAVNL
Sbjct: 74 FGHMEAVNL 82
>NP_055018
          Length = 977

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          F  +EAVNL
Sbjct: 74 FGHMEAVNL 82
>NP_001008212
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_068815
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_001008214
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>NP_001008213
          Length = 577

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 297 SEVEALNL 304
>XP_005257093
          Length = 246

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FSELEAVNL 9
           FSELEA  L
Sbjct: 119 FSELEAKQL 127
>XP_005257092
          Length = 209

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          FSELEA  L
Sbjct: 82 FSELEAKQL 90
>XP_005257091
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FSELEAVNL 9
           FSELEA  L
Sbjct: 152 FSELEAKQL 160
>XP_005257090
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FSELEAVNL 9
           FSELEA  L
Sbjct: 152 FSELEAKQL 160
>XP_005252395
          Length = 520

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 240 SEVEALNL 247
>XP_005252394
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 291 SEVEALNL 298
>XP_005252393
          Length = 571

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   SELEAVNL 9
           SE+EA+NL
Sbjct: 291 SEVEALNL 298
>NP_859058
          Length = 236

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1   FSELEAVNL 9
           FSELEA  L
Sbjct: 119 FSELEAKQL 127
>NP_001273545
          Length = 955

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FSELEAVN 8
          F ELEAV+
Sbjct: 62 FDELEAVS 69
>NP_849148
          Length = 920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FSELEAVN 8
          F ELEAV+
Sbjct: 27 FDELEAVS 34
>NP_001273544
          Length = 955

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  FSELEAVN 8
          F ELEAV+
Sbjct: 62 FDELEAVS 69
>NP_055136
          Length = 252

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FSELEAVNL 9
           FS +EAVN+
Sbjct: 105 FSCIEAVNM 113
>NP_055651
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>NP_001153508
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 168 YADLEAVN 175
>NP_001229288
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006718152
          Length = 530

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006718151
          Length = 591

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006718150
          Length = 621

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006718149
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006718148
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006718147
          Length = 696

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>XP_006716378
          Length = 749

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 168 YADLEAVN 175
>NP_001153509
          Length = 734

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 153 YADLEAVN 160
>NP_055993
          Length = 727

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FSELEAVN 8
           +++LEAVN
Sbjct: 146 YADLEAVN 153
>NP_004490
          Length = 285

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FSELEAVNL 9
           F E+EA+ L
Sbjct: 177 FGEIEAIEL 185
>NP_112556
          Length = 332

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FSELEAVNL 9
           F E+EA+ L
Sbjct: 177 FGEIEAIEL 185
>NP_055835
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSELEAVNL 9
           FS+L+ +NL
Sbjct: 298 FSQLKGLNL 306
>NP_001275932
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FSELEAVNL 9
           FS+L+ +NL
Sbjct: 298 FSQLKGLNL 306
>NP_001099038
          Length = 1749

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1486 NELEAIN 1492
>NP_001099037
          Length = 1757

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1486 NELEAIN 1492
>NP_001099036
          Length = 1770

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1499 NELEAIN 1505
>NP_071396
          Length = 1805

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1534 NELEAIN 1540
>XP_006715230
          Length = 1734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1463 NELEAIN 1469
>XP_006715229
          Length = 1782

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1511 NELEAIN 1517
>XP_005249350
          Length = 1810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1539 NELEAIN 1545
>XP_005249349
          Length = 1824

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1553 NELEAIN 1559
>XP_005249348
          Length = 1832

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1561 NELEAIN 1567
>XP_005249347
          Length = 1837

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1574 NELEAIN 1580
>XP_005249346
          Length = 1845

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    SELEAVN 8
            +ELEA+N
Sbjct: 1574 NELEAIN 1580
>NP_778227
          Length = 348

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  FSELEAVNL 9
          FS+ EAV L
Sbjct: 5  FSQAEAVEL 13
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.313    0.130    0.318 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 424,994
Number of extensions: 612
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)

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