Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

XP_005264851                                                           16    5631
XP_005264850                                                           16    5631
XP_006712984                                                           16    5631
XP_005264847                                                           16    5631
NP_077008                                                              16    7355
NP_055486                                                              16    7355
XP_006722947                                                           16    7355
XP_005249622                                                           16    7355
XP_005249621                                                           16    7355
NP_001252516                                                           15    9605
NP_001020775                                                           15    9605
>XP_005264851
          Length = 163

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SVGVSAS 9
           SVGVSAS
Sbjct: 102 SVGVSAS 108
>XP_005264850
          Length = 171

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SVGVSAS 9
           SVGVSAS
Sbjct: 110 SVGVSAS 116
>XP_006712984
          Length = 279

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SVGVSAS 9
           SVGVSAS
Sbjct: 260 SVGVSAS 266
>XP_005264847
          Length = 321

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   SVGVSAS 9
           SVGVSAS
Sbjct: 260 SVGVSAS 266
>NP_077008
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRSVGVSAS 9
           FR++G+S S
Sbjct: 106 FRALGISIS 114
>NP_055486
          Length = 1083

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRSVGVSAS 9
           F+S+GV+ S
Sbjct: 576 FQSIGVTTS 584
>XP_006722947
          Length = 412

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRSVGVSAS 9
           FR++G+S S
Sbjct: 106 FRALGISIS 114
>XP_005249622
          Length = 1021

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRSVGVSAS 9
           F+S+GV+ S
Sbjct: 576 FQSIGVTTS 584
>XP_005249621
          Length = 1058

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRSVGVSAS 9
           F+S+GV+ S
Sbjct: 551 FQSIGVTTS 559
>NP_001252516
          Length = 157

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  FRSVGVS 7
          F+SVG+S
Sbjct: 88 FQSVGIS 94
>NP_001020775
          Length = 402

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2  RSVGVSA 8
          RSVGV+A
Sbjct: 60 RSVGVNA 66
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.318    0.124    0.311 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 351,058
Number of extensions: 331
Number of successful extensions: 11
Number of sequences better than 10000.0: 11
Number of HSP's gapped: 11
Number of HSP's successfully gapped: 11
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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