Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004324                                                              18    1482
NP_002871                                                              18    1482
XP_005250103                                                           18    1482
XP_005250102                                                           18    1482
XP_005265416                                                           18    1482
XP_005265415                                                           18    1482
XP_005265414                                                           18    1482
XP_005265412                                                           18    1482
NP_001243125                                                           17    3301
NP_001645                                                              17    3301
XP_006724592                                                           17    3301
NP_775859                                                              17    4312
NP_001254542                                                           16    5631
NP_001254539                                                           16    5631
NP_001254543                                                           16    5631
NP_722561                                                              16    5631
NP_001254538                                                           16    5631
NP_001254540                                                           16    5631
NP_001254541                                                           16    5631
XP_006711316                                                           16    5631
XP_005245114                                                           16    5631
XP_005245113                                                           16    5631
XP_006711315                                                           16    5631
XP_005245112                                                           16    5631
XP_006711314                                                           16    5631
NP_004450                                                              16    7355
NP_872579                                                              16    7355
XP_005257219                                                           16    7355
XP_005257218                                                           16    7355
XP_005257217                                                           16    7355
XP_005257216                                                           16    7355
XP_005257215                                                           16    7355
XP_005257214                                                           16    7355
XP_005257213                                                           16    7355
XP_005257212                                                           16    7355
XP_006721834                                                           16    7355
XP_005257211                                                           16    7355
XP_005257210                                                           16    7355
XP_005257209                                                           16    7355
XP_005257208                                                           16    7355
XP_006721833                                                           16    7355
XP_005257207                                                           16    7355
XP_006719085                                                           16    7355
XP_006719083                                                           16    7355
NP_036204                                                              15    9605
NP_005277                                                              15    9605
>NP_004324
          Length = 766

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 595 FGLATVKSR 603
>NP_002871
          Length = 648

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 487 FGLATVKSR 495
>XP_005250103
          Length = 758

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 595 FGLATVKSR 603
>XP_005250102
          Length = 767

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 595 FGLATVKSR 603
>XP_005265416
          Length = 534

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 373 FGLATVKSR 381
>XP_005265415
          Length = 567

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 406 FGLATVKSR 414
>XP_005265414
          Length = 615

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 454 FGLATVKSR 462
>XP_005265412
          Length = 648

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVKSR
Sbjct: 487 FGLATVKSR 495
>NP_001243125
          Length = 609

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVK+R
Sbjct: 451 FGLATVKTR 459
>NP_001645
          Length = 606

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVK+R
Sbjct: 448 FGLATVKTR 456
>XP_006724592
          Length = 611

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           F LATVK+R
Sbjct: 453 FGLATVKTR 461
>NP_775859
          Length = 1326

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   RLATVKS 8
           RLATVKS
Sbjct: 512 RLATVKS 518
>NP_001254542
          Length = 451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 134 FRVARVKAR 142
>NP_001254539
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 212 FRVARVKAR 220
>NP_001254543
          Length = 415

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 98  FRVARVKAR 106
>NP_722561
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 212 FRVARVKAR 220
>NP_001254538
          Length = 549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 232 FRVARVKAR 240
>NP_001254540
          Length = 546

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 229 FRVARVKAR 237
>NP_001254541
          Length = 397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  FRLATVKSR 9
          FR+A VK+R
Sbjct: 80 FRVARVKAR 88
>XP_006711316
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 212 FRVARVKAR 220
>XP_005245114
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 212 FRVARVKAR 220
>XP_005245113
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 212 FRVARVKAR 220
>XP_006711315
          Length = 529

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 212 FRVARVKAR 220
>XP_005245112
          Length = 549

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 232 FRVARVKAR 240
>XP_006711314
          Length = 552

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   FRLATVKSR 9
           FR+A VK+R
Sbjct: 235 FRVARVKAR 243
>NP_004450
          Length = 2903

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>NP_872579
          Length = 2920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1769 YRLQTVKS 1776
>XP_005257219
          Length = 2038

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257218
          Length = 2957

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257217
          Length = 2961

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257216
          Length = 3015

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257215
          Length = 3032

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1769 YRLQTVKS 1776
>XP_005257214
          Length = 3094

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1831 YRLQTVKS 1838
>XP_005257213
          Length = 3095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1832 YRLQTVKS 1839
>XP_005257212
          Length = 3095

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1832 YRLQTVKS 1839
>XP_006721834
          Length = 3100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257211
          Length = 3100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257210
          Length = 3104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257209
          Length = 3148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257208
          Length = 3157

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1894 YRLQTVKS 1901
>XP_006721833
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_005257207
          Length = 3158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    FRLATVKS 8
            +RL TVKS
Sbjct: 1895 YRLQTVKS 1902
>XP_006719085
          Length = 684

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLATVKSR 9
           +LATVKS+
Sbjct: 625 QLATVKSK 632
>XP_006719083
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RLATVKSR 9
           +LATVKS+
Sbjct: 676 QLATVKSK 683
>NP_036204
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  LATVKSR 9
          LATVKS+
Sbjct: 60 LATVKSK 66
>NP_005277
          Length = 333

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LATVKSR 9
           LATV+SR
Sbjct: 147 LATVRSR 153
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.337    0.135    0.350 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 240,192
Number of extensions: 314
Number of successful extensions: 46
Number of sequences better than 10000.0: 46
Number of HSP's gapped: 46
Number of HSP's successfully gapped: 46
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.5 bits)
S2: 28 (15.4 bits)

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