Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001121619                                                           21     175
NP_000258                                                              21     175
NP_001035957                                                           21     175
XP_006721991                                                           21     175
XP_006721990                                                           21     175
XP_006721989                                                           21     175
XP_005258041                                                           21     175
XP_006721988                                                           21     175
XP_006721987                                                           21     175
XP_006721986                                                           21     175
XP_005258040                                                           21     175
XP_006721985                                                           21     175
NP_001120694                                                           17    4312
NP_075461                                                              17    4312
NP_001120693                                                           17    4312
NP_000059                                                              17    4312
NP_001167551                                                           17    4312
NP_115560                                                              16    5631
NP_060919                                                              16    5631
NP_001269458                                                           16    5631
XP_005271313                                                           16    5631
XP_005271309                                                           16    5631
XP_006711008                                                           16    5631
NP_115865                                                              16    5631
NP_001008779                                                           16    7355
NP_877433                                                              16    7355
NP_001136106                                                           16    7355
NP_776175                                                              16    7355
NP_009143                                                              16    7355
NP_065973                                                              16    7355
NP_001002838                                                           16    7355
XP_006724657                                                           16    7355
XP_006724656                                                           16    7355
XP_005254368                                                           16    7355
XP_005254367                                                           16    7355
XP_006720536                                                           16    7355
XP_005268430                                                           16    7355
XP_006711625                                                           16    7355
XP_005245470                                                           16    7355
NP_005889                                                              16    7355
NP_976240                                                              16    7355
NP_077288                                                              15    9605
NP_000050                                                              15    9605
NP_001612                                                              15    9605
NP_008977                                                              15    9605
NP_998820                                                              15    9605
NP_001171914                                                           15    9605
NP_065847                                                              15    9605
NP_006530                                                              15    9605
NP_055843                                                              15    9605
NP_005291                                                              15    9605
NP_001155038                                                           15    9605
NP_001155037                                                           15    9605
NP_001155036                                                           15    9605
NP_001155035                                                           15    9605
NP_001155034                                                           15    9605
NP_001155033                                                           15    9605
NP_001155032                                                           15    9605
NP_001164433                                                           15    9605
NP_001546                                                              15    9605
NP_001164432                                                           15    9605
XP_006724819                                                           15    9605
XP_006724818                                                           15    9605
XP_005272654                                                           15    9605
XP_005256177                                                           15    9605
XP_005255094                                                           15    9605
XP_006719656                                                           15    9605
XP_005272098                                                           15    9605
XP_006714726                                                           15    9605
XP_006711991                                                           15    9605
NP_001091048                                                           15    9605
NP_006741                                                              15    9605
>NP_001121619
          Length = 593

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>NP_000258
          Length = 2818

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>NP_001035957
          Length = 2839

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721991
          Length = 1632

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721990
          Length = 2823

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721989
          Length = 2823

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_005258041
          Length = 2836

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721988
          Length = 2846

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721987
          Length = 2849

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721986
          Length = 2854

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 371 FRISPHNNQ 379
>XP_005258040
          Length = 2857

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>XP_006721985
          Length = 2867

 Score = 21.2 bits (43), Expect =   175
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   FRISTHNNQ 9
           FRIS HNNQ
Sbjct: 384 FRISPHNNQ 392
>NP_001120694
          Length = 2506

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FRISTHNN 8
            F+I+ HNN
Sbjct: 1730 FQITEHNN 1737
>NP_075461
          Length = 2512

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FRISTHNN 8
            F+I+ HNN
Sbjct: 1736 FQITEHNN 1743
>NP_001120693
          Length = 2261

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FRISTHNN 8
            F+I+ HNN
Sbjct: 1731 FQITEHNN 1738
>NP_000059
          Length = 2266

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FRISTHNN 8
            F+I+ HNN
Sbjct: 1736 FQITEHNN 1743
>NP_001167551
          Length = 2263

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FRISTHNN 8
            F+I+ HNN
Sbjct: 1733 FQITEHNN 1740
>NP_115560
          Length = 1194

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STHNN+
Sbjct: 994 STHNNR 999
>NP_060919
          Length = 1119

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FRISTHNNQ 9
           F  S HNNQ
Sbjct: 325 FTNSQHNNQ 333
>NP_001269458
          Length = 852

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  FRISTHNNQ 9
          F  S HNNQ
Sbjct: 58 FTNSQHNNQ 66
>XP_005271313
          Length = 936

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STHNN+
Sbjct: 736 STHNNR 741
>XP_005271309
          Length = 1228

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    STHNNQ 9
            STHNN+
Sbjct: 1191 STHNNR 1196
>XP_006711008
          Length = 1262

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4    STHNNQ 9
            STHNN+
Sbjct: 1191 STHNNR 1196
>NP_115865
          Length = 125

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FRISTHNNQ 9
          +RIS H+ Q
Sbjct: 49 YRISAHSQQ 57
>NP_001008779
          Length = 286

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  FRISTHNN 8
          F  +THNN
Sbjct: 46 FEKNTHNN 53
>NP_877433
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  FRISTHNN 8
          F  +THNN
Sbjct: 46 FEKNTHNN 53
>NP_001136106
          Length = 313

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  FRISTHNN 8
          F  +THNN
Sbjct: 46 FEKNTHNN 53
>NP_776175
          Length = 1150

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FRISTHNN 8
           FR+ST N+
Sbjct: 556 FRLSTENS 563
>NP_009143
          Length = 336

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STH+NQ
Sbjct: 183 STHSNQ 188
>NP_065973
          Length = 1800

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           ++ THNN+
Sbjct: 762 QLETHNNK 769
>NP_001002838
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           ++ THNN+
Sbjct: 762 QLETHNNK 769
>XP_006724657
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           ++ THNN+
Sbjct: 762 QLETHNNK 769
>XP_006724656
          Length = 1743

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           ++ THNN+
Sbjct: 762 QLETHNNK 769
>XP_005254368
          Length = 712

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FRISTHNN 8
           FR+ST N+
Sbjct: 556 FRLSTENS 563
>XP_005254367
          Length = 1031

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FRISTHNN 8
           FR+ST N+
Sbjct: 437 FRLSTENS 444
>XP_006720536
          Length = 1072

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FRISTHNN 8
           FR+ST N+
Sbjct: 478 FRLSTENS 485
>XP_005268430
          Length = 735

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   ISTHNN 8
           IS+HNN
Sbjct: 142 ISSHNN 147
>XP_006711625
          Length = 557

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STH+NQ
Sbjct: 533 STHHNQ 538
>XP_005245470
          Length = 287

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STH+NQ
Sbjct: 134 STHSNQ 139
>NP_005889
          Length = 709

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STHN+Q
Sbjct: 248 STHNHQ 253
>NP_976240
          Length = 694

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   STHNNQ 9
           STHN+Q
Sbjct: 248 STHNHQ 253
>NP_077288
          Length = 1256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   FRISTHNNQ 9
           FR+ TH  +
Sbjct: 816 FRVETHTQK 824
>NP_000050
          Length = 3418

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1    FRISTHNNQ 9
            F+I  HN++
Sbjct: 1273 FKIENHNDK 1281
>NP_001612
          Length = 848

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FRISTHNNQ 9
           FR+ T NN+
Sbjct: 351 FRLLTKNNR 359
>NP_008977
          Length = 1016

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 250 RVSTHDQE 257
>NP_998820
          Length = 2634

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3    ISTHNNQ 9
            + THNN+
Sbjct: 1039 VLTHNNE 1045
>NP_001171914
          Length = 2642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 3   ISTHNNQ 9
           + THNN+
Sbjct: 954 VLTHNNE 960
>NP_065847
          Length = 1030

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ISTHNNQ 9
           +S+HN+Q
Sbjct: 622 VSSHNHQ 628
>NP_006530
          Length = 315

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           F+ S HNN
Sbjct: 299 FKESLHNN 306
>NP_055843
          Length = 1360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 949 RVSTHSQE 956
>NP_005291
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FRISTHNNQ 9
           FRI  H NQ
Sbjct: 109 FRIMYHINQ 117
>NP_001155038
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 857 RVSTHSQE 864
>NP_001155037
          Length = 1276

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 865 RVSTHSQE 872
>NP_001155036
          Length = 1297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 886 RVSTHSQE 893
>NP_001155035
          Length = 1305

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 894 RVSTHSQE 901
>NP_001155034
          Length = 1323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 912 RVSTHSQE 919
>NP_001155033
          Length = 1331

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 920 RVSTHSQE 927
>NP_001155032
          Length = 1352

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 941 RVSTHSQE 948
>NP_001164433
          Length = 1327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           +R+ TH N
Sbjct: 477 YRVETHPN 484
>NP_001546
          Length = 1336

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           +R+ TH N
Sbjct: 486 YRVETHPN 493
>NP_001164432
          Length = 1341

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           +R+ TH N
Sbjct: 486 YRVETHPN 493
>XP_006724819
          Length = 1253

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           +R+ TH N
Sbjct: 486 YRVETHPN 493
>XP_006724818
          Length = 1304

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           +R+ TH N
Sbjct: 486 YRVETHPN 493
>XP_005272654
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FRISTHNNQ 9
           FRI  H NQ
Sbjct: 109 FRIMYHINQ 117
>XP_005256177
          Length = 373

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           FR+ TH +
Sbjct: 250 FRVETHRD 257
>XP_005255094
          Length = 268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           F+ S HNN
Sbjct: 252 FKESLHNN 259
>XP_006719656
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 6/9 (66%)

Query: 1   FRISTHNNQ 9
           FR+ TH  +
Sbjct: 816 FRVETHTQK 824
>XP_005272098
          Length = 1047

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ISTHNNQ 9
           +S+HN+Q
Sbjct: 639 VSSHNHQ 645
>XP_006714726
          Length = 1052

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   ISTHNNQ 9
           +S+HN+Q
Sbjct: 644 VSSHNHQ 650
>XP_006711991
          Length = 970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2   RISTHNNQ 9
           R+STH+ +
Sbjct: 250 RVSTHDQE 257
>NP_001091048
          Length = 381

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   FRISTHNNQ 9
           FRI  H NQ
Sbjct: 109 FRIMYHINQ 117
>NP_006741
          Length = 540

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 6/8 (75%)

Query: 1   FRISTHNN 8
           FR+ TH +
Sbjct: 417 FRVETHRD 424
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.323    0.126    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 599,809
Number of extensions: 1092
Number of successful extensions: 72
Number of sequences better than 10000.0: 72
Number of HSP's gapped: 72
Number of HSP's successfully gapped: 72
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package