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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_689966                                                              18    1482
XP_005249005                                                           18    1482
XP_005249004                                                           18    1482
XP_005249003                                                           18    1482
XP_005249000                                                           18    1482
NP_008862                                                              17    4312
NP_001273164                                                           17    4312
NP_001273166                                                           17    4312
NP_001273163                                                           17    4312
NP_001273162                                                           17    4312
NP_703150                                                              17    4312
NP_001273165                                                           17    4312
NP_001092908                                                           17    4312
NP_001092907                                                           17    4312
NP_919306                                                              17    4312
XP_005253374                                                           17    4312
XP_005253372                                                           17    4312
NP_705834                                                              17    4312
NP_689813                                                              16    5631
NP_001269939                                                           16    7355
NP_001269938                                                           16    7355
NP_116575                                                              16    7355
NP_057518                                                              16    7355
NP_056036                                                              16    7355
NP_570969                                                              16    7355
NP_004810                                                              16    7355
NP_001037853                                                           16    7355
NP_001037852                                                           16    7355
NP_077317                                                              16    7355
XP_006723946                                                           16    7355
XP_005259343                                                           16    7355
XP_006717798                                                           16    7355
XP_005276017                                                           16    7355
NP_000375                                                              15    9605
NP_443128                                                              15    9605
NP_644810                                                              15    9605
NP_056068                                                              15    9605
NP_055692                                                              15    9605
XP_005276647                                                           15    9605
XP_005276648                                                           15    9605
XP_006726767                                                           15    9605
XP_005257947                                                           15    9605
XP_005257946                                                           15    9605
XP_005257945                                                           15    9605
XP_006722277                                                           15    9605
XP_005256630                                                           15    9605
XP_005256629                                                           15    9605

>NP_689966
          Length = 993

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RISSFLRP 9
           ++SSFLRP
Sbjct: 984 KVSSFLRP 991



>XP_005249005
          Length = 531

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RISSFLRP 9
           ++SSFLRP
Sbjct: 522 KVSSFLRP 529



>XP_005249004
          Length = 955

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RISSFLRP 9
           ++SSFLRP
Sbjct: 946 KVSSFLRP 953



>XP_005249003
          Length = 987

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   RISSFLRP 9
           ++SSFLRP
Sbjct: 978 KVSSFLRP 985



>XP_005249000
          Length = 1009

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    RISSFLRP 9
            ++SSFLRP
Sbjct: 1000 KVSSFLRP 1007



>NP_008862
          Length = 496

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 261 FRVSSYRQP 269



>NP_001273164
          Length = 497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 262 FRVSSYRQP 270



>NP_001273166
          Length = 535

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 300 FRVSSYRQP 308



>NP_001273163
          Length = 497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 262 FRVSSYRQP 270



>NP_001273162
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 285 FRVSSYRQP 293



>NP_703150
          Length = 520

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 285 FRVSSYRQP 293



>NP_001273165
          Length = 411

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 176 FRVSSYRQP 184



>NP_001092908
          Length = 624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FRISSFL 7
           FR+SSFL
Sbjct: 354 FRLSSFL 360




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FRISSFL 7
           FR++SFL
Sbjct: 578 FRLNSFL 584



>NP_001092907
          Length = 624

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FRISSFL 7
           FR+SSFL
Sbjct: 354 FRLSSFL 360




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FRISSFL 7
           FR++SFL
Sbjct: 578 FRLNSFL 584



>NP_919306
          Length = 623

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   FRISSFL 7
           FR+SSFL
Sbjct: 353 FRLSSFL 359




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FRISSFL 7
           FR++SFL
Sbjct: 577 FRLNSFL 583



>XP_005253374
          Length = 497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 262 FRVSSYRQP 270



>XP_005253372
          Length = 497

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FRISSFLRP 9
           FR+SS+ +P
Sbjct: 262 FRVSSYRQP 270



>NP_705834
          Length = 594

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RISSFLR 8
           R+SSFLR
Sbjct: 525 RVSSFLR 531



>NP_689813
          Length = 562

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1   FRISSFLR 8
           FR++S+LR
Sbjct: 307 FRLASYLR 314



>NP_001269939
          Length = 996

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RISSFLR 8
           +ISSFLR
Sbjct: 957 KISSFLR 963



>NP_001269938
          Length = 1300

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RISSFLR 8
            +ISSFLR
Sbjct: 1180 KISSFLR 1186



>NP_116575
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RISSFLR 8
            +ISSFLR
Sbjct: 1204 KISSFLR 1210



>NP_057518
          Length = 1219

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RISSFLR 8
            +ISSFLR
Sbjct: 1180 KISSFLR 1186



>NP_056036
          Length = 1577

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FRISSFLRP 9
            F  SSFL+P
Sbjct: 1337 FVYSSFLKP 1345



>NP_570969
          Length = 605

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   RISSFLR 8
           +ISSFLR
Sbjct: 533 KISSFLR 539



>NP_004810
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FRISSFLRP 9
           FR+S  L+P
Sbjct: 544 FRLSDVLKP 552



>NP_001037853
          Length = 423

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FRISSFLRP 9
           F  SS+LRP
Sbjct: 238 FSNSSYLRP 246



>NP_001037852
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FRISSFLRP 9
           F  SS+LRP
Sbjct: 245 FSNSSYLRP 253



>NP_077317
          Length = 430

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   FRISSFLRP 9
           F  SS+LRP
Sbjct: 245 FSNSSYLRP 253



>XP_006723946
          Length = 1414

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    ISSFLRP 9
            ++SFLRP
Sbjct: 1386 LASFLRP 1392



>XP_005259343
          Length = 1274

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FRISSFLRP 9
           FR+S  L+P
Sbjct: 544 FRLSDVLKP 552



>XP_006717798
          Length = 1534

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    FRISSFLRP 9
            F  SSFL+P
Sbjct: 1294 FVYSSFLKP 1302



>XP_005276017
          Length = 610

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           ++SFLRP
Sbjct: 571 LASFLRP 577



>NP_000375
          Length = 4563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1    FRISSF 6
            FR+SSF
Sbjct: 1490 FRVSSF 1495



>NP_443128
          Length = 3487

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    RISSFLR 8
            +ISSFLR
Sbjct: 2081 QISSFLR 2087



>NP_644810
          Length = 951

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FRISSFLRP 9
           F+IS+ L P
Sbjct: 205 FKISAILHP 213



>NP_056068
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  FRISSFLR 8
          FR+  FLR
Sbjct: 6  FRLQKFLR 13



>NP_055692
          Length = 1942

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  FRISSFLR 8
          +RI+SFL+
Sbjct: 62 YRIASFLQ 69



>XP_005276647
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 119 VSSWLRP 125




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 252 VSSWLRP 258




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 404 VSSWLRP 410



>XP_005276648
          Length = 596

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 119 VSSWLRP 125




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 252 VSSWLRP 258




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 404 VSSWLRP 410



>XP_006726767
          Length = 615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 119 VSSWLRP 125




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 252 VSSWLRP 258




 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   ISSFLRP 9
           +SS+LRP
Sbjct: 404 VSSWLRP 410



>XP_005257947
          Length = 1935

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  FRISSFLR 8
          +RI+SFL+
Sbjct: 62 YRIASFLQ 69



>XP_005257946
          Length = 1943

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  FRISSFLR 8
          +RI+SFL+
Sbjct: 62 YRIASFLQ 69



>XP_005257945
          Length = 1969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  FRISSFLR 8
          +RI+SFL+
Sbjct: 62 YRIASFLQ 69



>XP_006722277
          Length = 1970

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1  FRISSFLR 8
          +RI+SFL+
Sbjct: 62 YRIASFLQ 69



>XP_005256630
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  FRISSFLR 8
          FR+  FLR
Sbjct: 6  FRLQKFLR 13



>XP_005256629
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 1  FRISSFLR 8
          FR+  FLR
Sbjct: 6  FRLQKFLR 13



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.346    0.154    0.473 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 434,703
Number of extensions: 827
Number of successful extensions: 56
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 56
Number of HSP's successfully gapped: 56
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.7 bits)
S2: 28 (15.4 bits)