Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000312                                                              22      79
NP_006452                                                              17    3301
NP_003310                                                              17    3301
NP_597676                                                              17    3301
NP_001243779                                                           17    3301
NP_596869                                                              17    3301
XP_006715715                                                           17    3301
XP_005246888                                                           17    3301
XP_006712788                                                           17    3301
XP_006712787                                                           17    3301
XP_006712786                                                           17    3301
NP_001254479                                                           17    3301
NP_597681                                                              17    3301
NP_775858                                                              17    4312
XP_005273989                                                           17    4312
NP_006784                                                              16    5631
NP_001087195                                                           16    5631
NP_001078955                                                           16    5631
NP_005401                                                              16    5631
NP_054817                                                              16    5631
NP_525021                                                              16    5631
NP_112217                                                              16    5631
NP_878918                                                              16    7355
NP_055995                                                              16    7355
NP_001278237                                                           16    7355
NP_001004471                                                           16    7355
NP_001165419                                                           16    7355
NP_076974                                                              16    7355
NP_001165420                                                           16    7355
XP_005260130                                                           16    7355
XP_006722946                                                           16    7355
XP_006720147                                                           16    7355
XP_005267517                                                           16    7355
XP_005267516                                                           16    7355
XP_005267515                                                           16    7355
XP_005267514                                                           16    7355
XP_005267513                                                           16    7355
XP_005267512                                                           16    7355
XP_005267511                                                           16    7355
XP_005264070                                                           16    7355
NP_789795                                                              16    7355
NP_001035545                                                           16    7355
NP_001047                                                              16    7355
NP_001268421                                                           15    9605
NP_000170                                                              15    9605
NP_001268422                                                           15    9605
NP_001268423                                                           15    9605
NP_001271230                                                           15    9605
NP_001271231                                                           15    9605
NP_940966                                                              15    9605
NP_061155                                                              15    9605
NP_057097                                                              15    9605
NP_848599                                                              15    9605
NP_056083                                                              15    9605
NP_055073                                                              15    9605
NP_006090                                                              15    9605
NP_075463                                                              15    9605
NP_001245243                                                           15    9605
XP_006723744                                                           15    9605
XP_005260304                                                           15    9605
XP_006720621                                                           15    9605
XP_006720620                                                           15    9605
XP_006720619                                                           15    9605
XP_006720618                                                           15    9605
XP_006719812                                                           15    9605
XP_006715810                                                           15    9605
XP_006715809                                                           15    9605
XP_005249083                                                           15    9605
XP_005247302                                                           15    9605
XP_006713081                                                           15    9605
XP_005246694                                                           15    9605
XP_005264328                                                           15    9605
NP_940888                                                              15    9605
>NP_000312
          Length = 928

 Score = 22.3 bits (46), Expect =    79
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   FQKINQMLC 9
           FQKINQM+C
Sbjct: 845 FQKINQMVC 853
>NP_006452
          Length = 1193

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QKINQMLC 9
            +K+NQ LC
Sbjct: 1028 EKLNQALC 1035
>NP_003310
          Length = 26926

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FQKINQMLC 9
            F+++N+ LC
Sbjct: 8844 FERVNKRLC 8852
>NP_597676
          Length = 27051

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FQKINQMLC 9
            F+++N+ LC
Sbjct: 8969 FERVNKRLC 8977
>NP_001243779
          Length = 34350

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1     FQKINQMLC 9
             F+++N+ LC
Sbjct: 16268 FERVNKRLC 16276
>NP_596869
          Length = 33423

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1     FQKINQMLC 9
             F+++N+ LC
Sbjct: 15341 FERVNKRLC 15349
>XP_006715715
          Length = 2023

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QKINQMLC 9
            +K+NQ LC
Sbjct: 2009 RKVNQSLC 2016
>XP_005246888
          Length = 22663

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FQKINQMLC 9
            F+++N+ LC
Sbjct: 4581 FERVNKRLC 4589
>XP_006712788
          Length = 24022

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FQKINQMLC 9
            F+++N+ LC
Sbjct: 5940 FERVNKRLC 5948
>XP_006712787
          Length = 33978

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1     FQKINQMLC 9
             F+++N+ LC
Sbjct: 15896 FERVNKRLC 15904
>XP_006712786
          Length = 35484

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1     FQKINQMLC 9
             F+++N+ LC
Sbjct: 17402 FERVNKRLC 17410
>NP_001254479
          Length = 35991

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1     FQKINQMLC 9
             F+++N+ LC
Sbjct: 17909 FERVNKRLC 17917
>NP_597681
          Length = 27118

 Score = 16.9 bits (32), Expect =  3301
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FQKINQMLC 9
            F+++N+ LC
Sbjct: 9036 FERVNKRLC 9044
>NP_775858
          Length = 523

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FQKINQML 8
           FQ+I QML
Sbjct: 154 FQRIQQML 161
>XP_005273989
          Length = 477

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FQKINQML 8
           FQ+I QML
Sbjct: 154 FQRIQQML 161
>NP_006784
          Length = 256

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FQKINQ 6
           FQK+NQ
Sbjct: 251 FQKVNQ 256
>NP_001087195
          Length = 411

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   INQMLC 9
           INQ+LC
Sbjct: 312 INQLLC 317
>NP_001078955
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   INQMLC 9
           INQ+LC
Sbjct: 282 INQLLC 287
>NP_005401
          Length = 381

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   INQMLC 9
           INQ+LC
Sbjct: 282 INQLLC 287
>NP_054817
          Length = 238

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FQKINQ 6
           FQK+NQ
Sbjct: 233 FQKVNQ 238
>NP_525021
          Length = 1543

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/9 (44%), Positives = 8/9 (88%)

Query: 1    FQKINQMLC 9
            ++K+N +LC
Sbjct: 1068 YEKLNLILC 1076
>NP_112217
          Length = 1594

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1    FQKINQMLC 9
            F+K NQ  C
Sbjct: 1523 FKKCNQQAC 1531
>NP_878918
          Length = 6907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>NP_055995
          Length = 6885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>NP_001278237
          Length = 99

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1  FQKINQMLC 9
          FQK  ++LC
Sbjct: 80 FQKRKEILC 88
>NP_001004471
          Length = 319

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   QKINQMLC 9
           Q+IN  LC
Sbjct: 177 QEINHFLC 184
>NP_001165419
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FQKINQML 8
          F+K N+ML
Sbjct: 38 FEKTNEML 45
>NP_076974
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FQKINQML 8
          F+K N+ML
Sbjct: 38 FEKTNEML 45
>NP_001165420
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FQKINQML 8
          F+K N+ML
Sbjct: 38 FEKTNEML 45
>XP_005260130
          Length = 104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FQKINQML 8
          F+K N+ML
Sbjct: 38 FEKTNEML 45
>XP_006722946
          Length = 176

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1  FQKINQML 8
          F+K N+ML
Sbjct: 38 FEKTNEML 45
>XP_006720147
          Length = 4788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267517
          Length = 6883

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267516
          Length = 6884

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267515
          Length = 6899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267514
          Length = 6908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267513
          Length = 6921

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267512
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005267511
          Length = 6922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            FQ+ NQ+L
Sbjct: 3967 FQRTNQLL 3974
>XP_005264070
          Length = 298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FQKINQML 8
           FQ++N ML
Sbjct: 145 FQRMNHML 152
>NP_789795
          Length = 307

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FQKINQML 8
           FQ++N ML
Sbjct: 154 FQRMNHML 161
>NP_001035545
          Length = 832

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 7/9 (77%)

Query: 1   FQKINQMLC 9
           +QK+ + LC
Sbjct: 109 YQKVERTLC 117
>NP_001047
          Length = 296

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FQKINQML 8
           FQ++N ML
Sbjct: 143 FQRMNHML 150
>NP_001268421
          Length = 1230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            F+K+NQ L
Sbjct: 1193 FEKMNQSL 1200
>NP_000170
          Length = 1360

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            F+K+NQ L
Sbjct: 1323 FEKMNQSL 1330
>NP_001268422
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            F+K+NQ L
Sbjct: 1021 FEKMNQSL 1028
>NP_001268423
          Length = 1058

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            F+K+NQ L
Sbjct: 1021 FEKMNQSL 1028
>NP_001271230
          Length = 1087

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QKINQML 8
            QK+NQ+L
Sbjct: 1063 QKLNQVL 1069
>NP_001271231
          Length = 1086

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QKINQML 8
            QK+NQ+L
Sbjct: 1062 QKLNQVL 1068
>NP_940966
          Length = 457

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QKINQML 8
          QKINQ++
Sbjct: 51 QKINQLV 57
>NP_061155
          Length = 1124

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QKINQML 8
            QK+NQ+L
Sbjct: 1100 QKLNQVL 1106
>NP_057097
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FQKINQM 7
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>NP_848599
          Length = 3092

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QKINQML 8
          QKINQ++
Sbjct: 51 QKINQLV 57
>NP_056083
          Length = 2243

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 2    QKINQMLC 9
            +++N++LC
Sbjct: 2174 EQVNEILC 2181
>NP_055073
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1  FQKINQMLC 9
          F K++ ++C
Sbjct: 47 FHKVDNLIC 55
>NP_006090
          Length = 628

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 6/9 (66%)

Query: 1   FQKINQMLC 9
           F K+N  LC
Sbjct: 212 FVKVNGKLC 220
>NP_075463
          Length = 3013

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    INQMLC 9
            INQ++C
Sbjct: 2688 INQLMC 2693
>NP_001245243
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  QKINQMLC 9
          +KIN++ C
Sbjct: 3  KKINKLFC 10
>XP_006723744
          Length = 847

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1  FQKINQMLC 9
          F K++ ++C
Sbjct: 47 FHKVDNLIC 55
>XP_005260304
          Length = 1530

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/9 (33%), Positives = 7/9 (77%)

Query: 1  FQKINQMLC 9
          F K++ ++C
Sbjct: 47 FHKVDNLIC 55
>XP_006720621
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FQKINQM 7
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006720620
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FQKINQM 7
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006720619
          Length = 293

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FQKINQM 7
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006720618
          Length = 327

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 1   FQKINQM 7
           FQ+ NQM
Sbjct: 230 FQRTNQM 236
>XP_006719812
          Length = 3019

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4    INQMLC 9
            INQ++C
Sbjct: 2688 INQLMC 2693
>XP_006715810
          Length = 1105

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QKINQML 8
            QK+NQ+L
Sbjct: 1081 QKLNQVL 1087
>XP_006715809
          Length = 1142

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2    QKINQML 8
            QK+NQ+L
Sbjct: 1118 QKLNQVL 1124
>XP_005249083
          Length = 255

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FQKINQMLC 9
           FQ+I+  LC
Sbjct: 208 FQEISWFLC 216
>XP_005247302
          Length = 2248

 Score = 15.4 bits (28), Expect =  9605
 Identities = 3/8 (37%), Positives = 8/8 (100%)

Query: 2    QKINQMLC 9
            +++N++LC
Sbjct: 2179 EQVNEILC 2186
>XP_006713081
          Length = 3964

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  QKINQML 8
          QKINQ++
Sbjct: 51 QKINQLV 57
>XP_005246694
          Length = 518

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  QKINQMLC 9
          +KIN++ C
Sbjct: 3  KKINKLFC 10
>XP_005264328
          Length = 1261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1    FQKINQML 8
            F+K+NQ L
Sbjct: 1224 FEKMNQSL 1231
>NP_940888
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FQKINQMLC 9
           FQ+I+  LC
Sbjct: 199 FQEISWFLC 207
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.342    0.142    0.466 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,296
Number of extensions: 1026
Number of successful extensions: 73
Number of sequences better than 10000.0: 73
Number of HSP's gapped: 73
Number of HSP's successfully gapped: 73
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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