Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001138775                                                           17    3301
NP_653287                                                              17    3301
XP_006726251                                                           17    3301
XP_006726250                                                           17    3301
XP_006726211                                                           17    3301
XP_006726210                                                           17    3301
XP_005277304                                                           17    3301
XP_006726113                                                           17    3301
XP_006726112                                                           17    3301
XP_006726014                                                           17    3301
XP_006726013                                                           17    3301
XP_006725926                                                           17    3301
XP_006725925                                                           17    3301
XP_005258605                                                           17    3301
XP_006725825                                                           17    3301
XP_005277355                                                           17    3301
XP_006725698                                                           17    3301
XP_005277126                                                           17    3301
XP_005278313                                                           17    3301
NP_001273767                                                           17    4312
NP_001501                                                              17    4312
NP_001487                                                              17    4312
XP_006714258                                                           17    4312
XP_005246847                                                           17    4312
XP_006712769                                                           17    4312
XP_006712768                                                           17    4312
XP_006712767                                                           17    4312
XP_006712766                                                           17    4312
XP_005246846                                                           17    4312
NP_005061                                                              17    4312
NP_963868                                                              17    4312
NP_064539                                                              16    5631
XP_005260495                                                           16    5631
NP_005606                                                              16    5631
NP_114409                                                              16    7355
NP_001231888                                                           16    7355
NP_001231891                                                           16    7355
NP_001231890                                                           16    7355
NP_001171809                                                           16    7355
NP_001098713                                                           16    7355
NP_065817                                                              16    7355
NP_777598                                                              16    7355
NP_003476                                                              16    7355
NP_001171147                                                           16    7355
NP_001231889                                                           16    7355
NP_057110                                                              16    7355
NP_001239579                                                           16    7355
XP_005268169                                                           16    7355
XP_006720326                                                           16    7355
XP_005268168                                                           16    7355
XP_006720325                                                           16    7355
XP_005268167                                                           16    7355
XP_005251939                                                           16    7355
NP_056183                                                              15    9605
NP_001264127                                                           15    9605
NP_787954                                                              15    9605
NP_059130                                                              15    9605
NP_057525                                                              15    9605
NP_056331                                                              15    9605
NP_001245139                                                           15    9605
NP_060220                                                              15    9605
NP_872293                                                              15    9605
XP_005254520                                                           15    9605
XP_005273949                                                           15    9605
XP_005251817                                                           15    9605
XP_006717052                                                           15    9605
XP_005264415                                                           15    9605
XP_005264414                                                           15    9605
NP_849151                                                              15    9605
NP_899231                                                              15    9605
>NP_001138775
          Length = 712

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 591 FPLVLLLGL 599
>NP_653287
          Length = 706

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 585 FPLVLLLGL 593
>XP_006726251
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006726250
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_006726211
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006726210
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_005277304
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006726113
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006726112
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_006726014
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006726013
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_006725926
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006725925
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_005258605
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006725825
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_005277355
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_006725698
          Length = 616

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 495 FPLVLLLGL 503
>XP_005277126
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>XP_005278313
          Length = 428

 Score = 16.9 bits (32), Expect =  3301
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP++LLL +
Sbjct: 307 FPLVLLLGL 315
>NP_001273767
          Length = 912

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FPIILLLSI 9
          FP +L+LS+
Sbjct: 4  FPFLLVLSV 12
>NP_001501
          Length = 1007

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FPIILLLSI 9
          FP +L+LS+
Sbjct: 4  FPFLLVLSV 12
>NP_001487
          Length = 400

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   PIILLLSI 9
           P+ILLLS+
Sbjct: 392 PLILLLSL 399
>XP_006714258
          Length = 994

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FPIILLLSI 9
          FP +L+LS+
Sbjct: 4  FPFLLVLSV 12
>XP_005246847
          Length = 1034

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   FPIILLLSI 9
           FP +LLL++
Sbjct: 983 FPFLLLLTV 991
>XP_006712769
          Length = 1059

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1008 FPFLLLLTV 1016
>XP_006712768
          Length = 1150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1099 FPFLLLLTV 1107
>XP_006712767
          Length = 1150

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1099 FPFLLLLTV 1107
>XP_006712766
          Length = 1179

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1128 FPFLLLLTV 1136
>XP_005246846
          Length = 1259

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1208 FPFLLLLTV 1216
>NP_005061
          Length = 1232

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1181 FPFLLLLTV 1189
>NP_963868
          Length = 1259

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    FPIILLLSI 9
            FP +LLL++
Sbjct: 1208 FPFLLLLTV 1216
>NP_064539
          Length = 242

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  FPIILLL 7
          FP++LLL
Sbjct: 9  FPVLLLL 15
>XP_005260495
          Length = 1330

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1    FPIILLL 7
            FP+ILL+
Sbjct: 1136 FPVILLI 1142
>NP_005606
          Length = 150

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  FPIILLLSI 9
          FP++LLL +
Sbjct: 5  FPLLLLLLV 13
>NP_114409
          Length = 467

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  FPIILLL 7
          FP++LLL
Sbjct: 11 FPLLLLL 17
>NP_001231888
          Length = 556

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FPIILLL 7
           FP++LLL
Sbjct: 543 FPLLLLL 549
>NP_001231891
          Length = 213

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FPIILLL 7
           FP++LLL
Sbjct: 200 FPLLLLL 206
>NP_001231890
          Length = 362

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FPIILLL 7
           FP++LLL
Sbjct: 349 FPLLLLL 355
>NP_001171809
          Length = 1148

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  PIILLLSI 9
          P++LLL+I
Sbjct: 7  PVLLLLAI 14
>NP_001098713
          Length = 1101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  PIILLLSI 9
          P++LLL+I
Sbjct: 7  PVLLLLAI 14
>NP_065817
          Length = 1100

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  PIILLLSI 9
          P++LLL+I
Sbjct: 7  PVLLLLAI 14
>NP_777598
          Length = 597

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FPIILLL 7
           FP++LLL
Sbjct: 543 FPLLLLL 549
>NP_003476
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 196 FPICLLLA 203
>NP_001171147
          Length = 365

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 196 FPICLLLA 203
>NP_001231889
          Length = 553

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FPIILLL 7
           FP++LLL
Sbjct: 499 FPLLLLL 505
>NP_057110
          Length = 318

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  FPIILLL 7
          FP++LLL
Sbjct: 6  FPLLLLL 12
>NP_001239579
          Length = 248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1  FPIILLL 7
          FP++LLL
Sbjct: 6  FPLLLLL 12
>XP_005268169
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 206 FPICLLLA 213
>XP_006720326
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 206 FPICLLLA 213
>XP_005268168
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 206 FPICLLLA 213
>XP_006720325
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 206 FPICLLLA 213
>XP_005268167
          Length = 375

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FPI LLL+
Sbjct: 206 FPICLLLA 213
>XP_005251939
          Length = 501

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   FPIILLL 7
           FP++LLL
Sbjct: 447 FPLLLLL 453
>NP_056183
          Length = 426

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   FPIILLL 7
           FP ILLL
Sbjct: 109 FPYILLL 115
>NP_001264127
          Length = 114

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   FPIILLLSI 9
           FP+ LLL +
Sbjct: 104 FPLALLLHV 112
>NP_787954
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FP++ LLS
Sbjct: 605 FPLVSLLS 612
>NP_059130
          Length = 1551

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FP++ LLS
Sbjct: 605 FPLVSLLS 612
>NP_057525
          Length = 1036

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PIILLLSI 9
           PII+ LSI
Sbjct: 946 PIIICLSI 953
>NP_056331
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FPIILLLSI 9
          +P++LLL++
Sbjct: 3  WPLLLLLAV 11
>NP_001245139
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FPIILLLSI 9
          +P++LLL++
Sbjct: 3  WPLLLLLAV 11
>NP_060220
          Length = 610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  PIILLLSI 9
          P++LLL++
Sbjct: 4  PLVLLLAV 11
>NP_872293
          Length = 652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PIILLLS 8
          P++LLLS
Sbjct: 15 PLVLLLS 21
>XP_005254520
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   FPIILLLS 8
           FP++ LLS
Sbjct: 289 FPLVSLLS 296
>XP_005273949
          Length = 367

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1  FPIILLLSI 9
          +P++LLL++
Sbjct: 17 WPLLLLLAV 25
>XP_005251817
          Length = 569

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PIILLLS 8
          P++LLLS
Sbjct: 15 PLVLLLS 21
>XP_006717052
          Length = 616

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  PIILLLS 8
          P++LLLS
Sbjct: 15 PLVLLLS 21
>XP_005264415
          Length = 971

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PIILLLSI 9
           PII+ LSI
Sbjct: 881 PIIICLSI 888
>XP_005264414
          Length = 978

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   PIILLLSI 9
           PII+ LSI
Sbjct: 888 PIIICLSI 895
>NP_849151
          Length = 147

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  PIILLLSI 9
          PI+LLL +
Sbjct: 41 PILLLLQV 48
>NP_899231
          Length = 328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   FPIILL 6
           FPI+LL
Sbjct: 279 FPIVLL 284
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.173    0.487 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 391,980
Number of extensions: 937
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

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